Vaccination in children with allergy to non active vaccine components

Review

Fabrizio Franceschini¹, Paolo Bottau², Silvia Caimmi³, Giuseppe Crisafulli⁴, Liotti Lucia⁵, Diego Peroni⁶, Francesca Saretta⁷, Mario Vernich⁸, Carlotta Povesi Dascola⁹ and Carlo Caffarelli^10*

Clinical and Translational Medicine 2015, 4:3  doi:10.1186/s40169-014-0043-0

Abstract

Childhood immunisation is one of the greatest public health successes of the last century. Vaccines contain an active component (the antigen) which induces the immune response. They may also contain additional components such as preservatives, additives, adjuvants and traces of other substances.

This review provides information about risks of hypersensitivity reactions to components of vaccines. Furthermore, recommendations to avoid or reduce reactions to vaccine components have been detailed.

Keywords: 

Hypersensitivity; Vaccine; allergy; Children; Egg. cow’s milk; Gelatin

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