Depigmented-polymerised allergoids favour regulatory over effector T cells: enhancement by 1α, 25-dihydroxyvitamin D3

Research article

Zoe L Urry¹, David F Richards¹, Cheryl Black¹, Maria Morales², Jerónimo Carnés²,Catherine M Hawrylowicz^1*† and Douglas S Robinson^3*†

• *Corresponding authors: Catherine M Hawrylowiczcatherine.hawrylowicz@kcl.ac.uk - Douglas S Robinsond.s.robinson@imperial.ac.uk
• † Equal contributors

Author Affiliations

¹Department of Allergy and Asthma, MRC and Asthma UK Centre for Mechanisms of Allergic Asthma, Guy’s Campus, King’s College London, London, UK

²Department of Research and Development, Laboratorios Leti, Tres Cantos, Madrid, Spain

³Leukocyte Biology Section, MRC and Asthma UK Centre for Mechanisms of Allergic Asthma, NHLI, Imperial College London, London, UK

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BMC Immunology 2014, 15:21  doi:10.1186/1471-2172-15-21

The electronic version of this article is the complete one and can be found online at:http://www.biomedcentral.com/1471-2172/15/21

Received:	30 October 2013
Accepted:	16 May 2014
Published:	29 May 2014

© 2014 Urry et al.; licensee BioMed Central Ltd. 

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

A Long-Term Risk? Prenatal POPs Exposure and Asthma in Young Adults

Environ Health Perspect; DOI:10.1289/ehp.122-A28

Lindsey Konkel is a Worcester, MA–based journalist who reports on science, health, and the environment. She is an editor for Environmental Health News and The Daily Climate.

About This Article open

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“The focus in immunotoxicity studies has often been on immunologic intermediates, such as immune cell counts. This study is unique in that it looks at a long-term clinically relevant outcome,” says Todd Jusko, an environmental epidemiologist at the University of Rochester, who was not involved in the study.lthough previous research has suggested that prenatal exposures to persistent organic pollutants (POPs) may be harmful to a child’s developing immune system,1 few studies have investigated long-term outcomes in this regard. Findings reported in this issue of EHP provide evidence that exposure to certain POPs in the womb may be associated with an increased risk of developing asthma that persists into young adulthood.2

Asthma and respiratory physiology: Putting lung function into perspective

Invited Review Series: Respiratory Disease: Using Lung Function Measurements to Greater Advantage

You have free access to this content

1. Giuseppe Francesco Sferrazza Papa¹,
2. Giulia Michela Pellegrino¹ and
3. Riccardo Pellegrino^2,*

Article first published online: 24 JUL 2014

DOI: 10.1111/resp.12355

© 2014 Asian Pacific Society of Respirology

Issue

Respirology

Volume 19, Issue 7, pages 960–969, October 2014

Additional Information(Show All)

How to CiteAuthor InformationPublication History

1. Watch the Video introducing the Review Series on lung function testing
2. The Authors: Giuseppe Francesco Sferrazza Papa, MD, is a Fellow in Respiratory Medicine with interest in chronic obstructive pulmonary diseases, lung function and imaging techniques. Giulia Michela Pellegrino, MD, is a Fellow in Respiratory Medicine with interest in chronic obstructive pulmonary diseases, lung function and clinical research. Riccardo Pellegrino, MD, is Chief of the Department of Allergology and Respiratory Pathophysiology with interest in chronic obstructive pulmonary diseases, lung and airway mechanics, airway hyperresponsiveness and exercise physiology.
3. Series Editors: Graham L. Hall and Charles G. Irvin
4. 
   

• NIHPA Author Manuscripts
• PMC3706515
• 
  • 
    

Pharmacogenomics J. Author manuscript; available in PMC Aug 1, 2014.

Published in final edited form as:

Pharmacogenomics J. Feb 2014; 14(1): 41–47.

Published online Mar 19, 2013. doi:  10.1038/tpj.2013.5

PMCID: PMC3706515

NIHMSID: NIHMS442409

A genome-wide association study of bronchodilator response in asthmatics

Qing Ling Duan, PhD,1,* Jessica Lasky-Su, ScD,1,* Blanca E. Himes, PhD,1,2 Weiliang Qiu, PhD,1 Augusto A. Litonjua, MD, MPH,1,3 Amy Damask, PhD,5 Ross Lazarus, MB, BS,1 Barbara Klanderman, PhD,1 Charles G. Irvin, PhD,6Stephen P. Peters, MD, PhD,7 John P. Hanrahan, MD, MPH,8 John J. Lima, PharmD,9 Fernando D. Martinez, MD,10David Mauger, PhD,11 Vernon M. Chinchilli, PhD,11 Manuel Soto-Quiros, PhD,12 Lydiana Avila, MD,12 Juan C. Celedón, MD, DrPH,13 Christoph Lange, PhD,4 Scott T. Weiss, MD, MS,1,2,3,4 and Kelan G. Tantisira, MD, MPH1,3

Author information ► Copyright and License information ►

Severe Asthma Study – Rob Oliphant - Asthma Society of Canada

Robert Oliphant is the President and CEO of the Asthma Society of Canada.  Rob is the President of the Global Allergy and Asthma Patient Platform and serves on the Steering Committee of Better Care Faster and the Governing Council of the Health Charities Coalition of Canada and was on the Steering Committee for the National Lung Health Framework. In 2013 he was awarded the Queen’s Diamond Jubilee Medal by the Governor General of Canada in recognition of his contributions to Canada.  From 2008 to 2011, Rob served as Member of Parliament of Canada, representing the riding of Don Valley West in the House of Commons.  Rob received his Bachelor of Commerce from the University of Toronto. He has a Masters of Divinity from the Vancouver School of Theology, at the University of British Columbia, and a Doctorate from the Chicago Theological Seminary at the University of Chicago.

Download the Presentation: Closing Presentation – Rob Oliphant | Severe Asthma Study – Rob Oliphant

Health Impact of Air Quality – Michael Brauer - Asthma Society of Canada

Michael Brauer is a Professor in the School of Population and Public Health at The University of British Columbia. He also directs the Bridge Program – a strategic training program linking public health, engineering and policy. His research focuses on the assessment of exposure and health impacts of air pollution, with specific interest in transportation-related and biomass air pollution. He has participated in monitoring and epidemiological studies throughout the world and served on advisory committees to the World Health Organization, the US National Academy of Sciences, the Royal Society of Canada, the International Joint Commission and governments in North America and Asia. He is an Associate Editor of Environmental Health Perspectives.

Download the Presentation: Health Impact of Air Quality – Michael Brauer

Corticosteroids in the treatment of acute asthma

REVIEW ARTICLE

Year : 2014  |  Volume : 9  |  Issue : 4  |  Page : 187-192

Abdullah A Alangari

Department of Pediatrics, College of Medicine, King Saud University, Riyadh, Saudi Arabia

Date of Submission    09-Dec-2013

Date of Acceptance    10-Mar-2014

Date of Web Publication    4-Sep-2014

DOI: 10.4103/1817-1737.140120

Small airway dysfunction is associated to excessive bronchoconstriction in asthmatic patients

Research

Veronica Alfieri¹, Marina Aiello¹, Roberta Pisi¹, Panagiota Tzani¹, Elisa Mariani¹, Emilio Marangio¹, Dario Olivieri¹, Gabriele Nicolini² and Alfredo Chetta^1*

• *Corresponding author: Alfredo Chetta chetta@unipr.it

Author Affiliations

¹Clinical & Experimental Medicine Department, University of Parma, Padiglione Rasori, via G. Rasori 10, Parma, 43125, Italy

²Corporate Clinical Development, Chiesi Farmaceutici S.p.A, Parma, Italy

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Respiratory Research 2014, 15:86  doi:10.1186/s12931-014-0086-1

The electronic version of this article is the complete one and can be found online at:http://respiratory-research.com/content/15/1/86

Received:	1 April 2014
Accepted:	20 July 2014
Published:	27 August 2014

© 2014 Alfieri et al.; licensee BioMed Central Ltd. 

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.