Different co-sensitizations could determine different risk assessment in peach allergy? Evaluation of an anaphylactic biomarker in Pru p 3 positive patients

• Carina Gabriela Uasuf, 
• Danilo Villalta, 
• Maria Elisabetta Conte, 
• Caterina Di Sano, 
• Maria Barrale, 
• Vincenzo Cantisano, 
• Elisabetta Pace,
• Mark Gjomarkaj, 
• Sebastiano Gangemi

and 

Ignazio Brusca

Clinical and Molecular Allergy201513:30

DOI: 10.1186/s12948-015-0035-7

Abstract

Background

In Italy, the nsLTP (Pru p 3) has been identified as the most frequent cause of food allergy and anaphylaxis. In order to estimate the risk assessment in peach allergy, we investigated the presence of correlations between the levels of sIgE to Pru p 3 with the severity of the clinical symptoms in two Pru p 3 positive populations from two different areas of Italy.

The Hidden Culprit: A Case of Repeated Anaphylaxis to Cremophor

Allergy Asthma Immunol Res. 2016 Mar;8(2):174-177. English. http://dx.doi.org/10.4168/aair.2016.8.2.174

Young Nam Kim, Jun Young Kim, Ji Won Kim, Jin Hae Kim, Hye In Kim, Sehyo Yune, Dong-Chull Choi andByung-Jae Lee

Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Abstract

Drug-induced anaphylaxis is a big pitfall in patients receiving antineoplastic chemotherapy. We report a case of lung cancer patient who experienced two near-fatal anaphylactic reactions that resulted from paclitaxel and multivitamin, seperately.

Review: Immunology of sinusitis, trauma, asthma, and sepsis

Authors: Frieri, Marianne; Kumar, Krishan; Boutin, Anthony

Source: Allergy & Rhinology, Volume 6, Number 3, 2015, pp. e205-e214(10)

Publisher: OceanSide Publications, Inc

Abstract:

Background: 

This review article is important for allergists/immunologists and otolaryngologists. It discussed chronic rhinosinusitis, epidemiology, pathogenesis, innate adaptive immunology, nuclear factor‐kappa B related to inflammation, sepsis, complement, reactive oxygen species, asthma, sinusitis, elderly pathogenesis, oxidative stress, depression, seasonal variation, vitamin D, genetic susceptibility and sepsis, hereditary angioedema related to trauma and stress. 

Allergy immunotherapy: the future of allergy treatment

Review

Drug Discovery Today

Volume 21, Issue 1, January 2016, Pages 26–37

Jørgen Nedergaard Larsen, 

Louise Broge, 

Henrik Jacobi

doi:10.1016/j.drudis.2015.07.010

  Open Access

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Highlights

•

Allergy is increasing in prevalence and pharmacotherapy alone cannot control the disease.

•

Allergy immunotherapy induces immunological tolerance and changes the course of disease.

•

Allergy immunotherapy has long term effect extending beyond termination of treatment.

•

Allergy immunotherapy prevents asthma in children with rhino-conjunctivitis.

•

Allergy immunotherapy improves quality-of-life in patients suffering from allergy.

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The hidden burden of adult allergic rhinitis: UK healthcare resource utilisation survey

Research

David Price^1*, Glenis Scadding², Dermot Ryan³⁴, Claus Bachert⁵, G. Walter Canonica⁶, Joaquim Mullol⁷, Ludger Klimek⁸, Richard Pitman⁹, Sarah Acaster¹⁰, Ruth Murray¹¹ and Jean Bousquet^12131415

Clinical and Translational Allergy 2015, 5:39  doi:10.1186/s13601-015-0083-6

Abstract

Background

The affliction of allergic rhinitis (AR) has been trivialised in the past. Recent initiatives by the European Academy of Allergy & Clinical Immunology and by the EU parliament seek to rectify that situation. The aim of this study was to provide a comprehensive picture of the burden and unmet need of AR patients.

Anaphylaxis following a transvaginal ultrasound

Case report

Baruch D. Jakubovic^1*, Corey Saperia² and Gordon L. Sussman¹²

Allergy, Asthma & Clinical Immunology 2016, 12:3  doi:10.1186/s13223-015-0106-9

Abstract

Polyethylene glycol is a ubiquitous, water-soluble, organic compound found in a wide variety of commercially available products. While generally a benign substance, in rare instances, it can induce hypersensitivity reactions. Herein, we describe a case of anaphylaxis to polyethylene glycol-containing lubricating gel used for a transvaginal ultrasound.

Treatment of Unexplained Chronic Cough: CHEST Guideline and Expert Panel Report

FREE TO VIEW

Peter Gibson, MBBS; Gang Wang, MD, PhD; Lorcan McGarvey, MD; Anne E. Vertigan, PhD, MBA, BAppSc (SpPath); Kenneth W. Altman, MD, PhD; Surinder S. Birring, MB ChB, MD

Author and Funding Information

Chest. 2016;149(1):27-44. doi:10.1378/chest.15-1496

Abstract

Abstract | Summary of Recommendations and Suggestions | Methods | Results | Discussion | Summary of the Systematic Review Results and Its Limitations | Future Directions | Conclusions |Acknowledgments | Supplementary Data | References

Background  Unexplained chronic cough (UCC) causes significant impairments in quality of life. Effective assessment and treatment approaches are needed for UCC.

Systematic review of the toxicity of short-course oral corticosteroids in children

Arch Dis Child doi:10.1136/archdischild-2015-309522

• Original article

 Authors

Abstract

Background Short-course oral corticosteroids are commonly used in children but are known to be associated with adverse drug reactions (ADRs). This review aimed to identify the most common and serious ADRs and to determine their relative risk levels.

Methods A literature search of EMBASE, MEDLINE, International Pharmaceutical Abstracts, CINAHL, Cochrane Library and PubMed was performed with no language restrictions to identify studies in which oral corticosteroids were administered to patients aged 28 days to 18 years of age for up to and including 14 days of treatment. Each database was searched from their earliest dates to December 2013. All studies providing clear information on ADRs were included.