June 17, 2016

Clinical Practice Guidelines for Diagnosis and Management of Hypersensitivity Reactions to Contrast Media

Rosado Ingelmo A1, Doña Diaz I2, Cabañas Moreno R3, Moya Quesada MC4, García-Avilés C5, García Nuñez I6, Martínez Tadeo JI7, Mielgo Ballesteros R8, Ortega-Rodríguez N9, Padial Vilchez MA10, Sánchez-Morillas L11, Vila Albelda C1, Moreno Rodilla E12*, Torres Jaén MJ2*

Abstract

The objective of these guidelines is to ensure efficient and effective clinical practice. The panel of experts who produced this consensus document developed a research protocol based on a review of the literature.
The prevalence of allergic reactions to iodinated contrast media (ICM) is estimated to be 1:170 000, that is, 0.05%-0.1% of patients undergoing radiologic studies with ICM (more than 75 million examinations per year worldwide).

What is new and upcoming in the world of chronic urticaria?


Special Issue: Chronic Urticaria. Challenges, Insights and New Directions. Proceedings of the second Global Urticaria Forum, November 2015, Berlin
Volume 30Issue Supplement S5pages 5–6July 2016

  1. M. Maurer1
  2. A.M. Giménez-Arnau2,* and
  3. T. Zuberbier1
This supplement presents a summary of the key topics discussed during plenary sessions, workshops and debates at the second international Global Urticaria Forum, which was held in Berlin, Germany in November 2015. This interactive meeting was an excellent opportunity to present new data (both from clinical studies and real-life experience) to the medical urticaria community and to gauge opinion on remaining unmet need and unanswered questions.

June 13, 2016

Analysis of the quality of life of patients with asthma and allergic rhinitis after immunotherapy

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PMCID: PMC4884771
Abstract
Aim
To assess the quality of life of Polish patients with asthma and/or allergic rhinitis before the implementation and after 30–36 months of immunotherapy.
Material and methods
Two hundred patients have been involved in the study: 101 with allergic asthma and 99 with pollinosis. In order to collect research material, the Polish versions of AQLQ (Asthma Quality of Life) and RQLQ (Rhinoconjunctivitis Quality of Life) questionnaires have been used.

Endotypes of allergic diseases and asthma: An important step in building blocks for the future of precision medicine

Article in Press
Abstract
Discoveries from basic science research in the last decade have brought significant progress in knowledge of pathophysiologic processes of allergic diseases, with a compelling impact on understanding of the natural history, risk prediction, treatment selection or mechanism-specific prevention strategies. The view of the pathophysiology of allergic diseases developed from a mechanistic approach, with a focus on symptoms and organ function, to the recognition of a complex network of immunological pathways. Several subtypes of inflammation and complex immune-regulatory networks and the reasons for their failure are now described, that open the way for the development of new diagnostic tools and innovative targeted-treatments.

June 8, 2016

MACVIA clinical decision algorithm in adolescents and adults with allergic rhinitis

The selection of pharmacotherapy for patients with allergic rhinitis (AR) depends on several factors, including age, prominent symptoms, symptom severity, control of AR, patient preferences, and cost. Allergen exposure and the resulting symptoms vary, and treatment adjustment is required. Clinical decision support systems (CDSSs) might be beneficial for the assessment of disease control. CDSSs should be based on the best evidence and algorithms to aid patients and health care professionals to jointly determine treatment and its step-up or step-down strategy depending on AR control.

June 7, 2016

Relation of the Timing of Onset of Rhinitis and Cough to Asthma Attack in Children

Summary: If the risk of progression to asthma could be predicted in patients with rhinitis, prevention of asthma might become possible. The purpose of this study was to clarify the relationship between the duration of rhinitis symptoms and acute asthma attacks in children with a history of asthma who were not on treatment for asthma. In 94 children with a history of asthma who were asymptomatic after completing asthma treatment, we investigated the onset and duration of nasal discharge and cough related to allergic rhinitis.

Maternal serum but not breast milk IL-5, IL-6, and IL-13 immune markers are associated with scratching among infants

 
OPEN ACCESS

  • Nelís Soto-Ramírez,
  • Keith Boyd,
  • Hongmei Zhang,
  • Venugopal Gangur,
  • Laura Goetzl and
  • Wilfried KarmausEmail author
Abstract
Background
Scratching in infants is considered to be related to early development of eczema. Little is known about the effects of maternal immune markers on scratching among infants. The objective is to compare the risks related to maternal serum immune markers (IMs) during pregnancy and IMs in breast milk for the occurrence of scratching in infants at 6 and 12 months of age.

June 6, 2016

Interactive digital interventions to promote self-management in adults with asthma: systematic review and meta-analysis


 
OPEN ACCESS
 
OPEN PEER REVIEW
  • Gary McLeanEmail author,
  • Elizabeth Murray,
  • Rebecca Band,
  • Keith R. Moffat,
  • Peter Hanlon,
  • Anne Bruton,
  • Mike Thomas,
  • Lucy Yardley and
  • Frances S. Mair


Abstract
Background
To identify, summarise and synthesise the evidence for using interactive digital interventions to support patient self-management of asthma, and determine their impact.
Methods
Systematic review with meta-analysis. We searched MEDLINE, EMBASE, CINAHL, PsycINFO, ERIC, Cochrane Library, DoPHER, TROPHI, Social Science Citation Index and Science Citation Index. The selection criteria requirement was studies of adults (16 years and over) with asthma, interventions that were interactive digital interventions and the comparator was usual care.