Background Symptoms of allergic rhinitis (AR) have a detrimental effect on quality of life. The AR-Patient Benefit Index (AR-PBI), a specific self-assessment tool has been developed to assess treatment-related benefit in two separate sections: the Patient Needs Questionnaire (PNQ) which explores the patient’s expectations before treatment and the Patient Benefit Questionnaire (PBQ) which evaluates treatment benefit. For the PNQ, three dimensions summarized patients’ expectations: symptoms, social life and emotional state, thus covering a larger field than symptomatic relief.
Thuy-My Le1*, Els van Hoffen110, Ischa Kummeling12, James Potts2, Barbara K Ballmer-Weber3, Carla AFM Bruijnzeel-Koomen1, Ans FM Lebens1, Jonas Lidholm4, Titia M Lindner1, Alan Mackie5, EN Clare Mills6, Ronald van Ree7, Stefan Vieths8, Montserrat Fernández-Rivas9, Peter G Burney2 and André C Knulst1
Background It is unknown whether food allergy (FA) in an unselected population is comparable to those from an outpatient clinic population. Objective To discover if FA in a random sample from the Dutch community is comparable to that of outpatients.
Background Asthma is the most common chronic condition of childhood and disproportionately affects inner-city minority children. Low rates of asthma preventer medication adherence is a major contributor to poor asthma control in these patients.
A considerable number of children with asthma remain symptomatic despite treatment with inhaled corticosteroids, resulting in significant morbidity, reduced quality of life, increased healthcare costs and lost school days.
Gordon Sussman1*, Jacques Hébert2, Wayne Gulliver3, Charles Lynde1, Susan Waserman4, Amin Kanani5, Moshe Ben-Shoshan6, Spencer Horemans1, Carly Barron1,Stephen Betschel1, William H Yang7, Jan Dutz5, Neil Shear1, Gina Lacuesta8, Peter Vadas1, Kenneth Kobayashi7, Hermenio Lima4 and F Estelle R Simons9
In the past few years there have been significant advances which have changed the face of chronic urticaria. In this review, we aim to update physicians about clinically relevant advances in the classification, diagnosis and management of chronic urticaria that have occurred in recent years.
Allergen exposure via the respiratory tract and in particular via the nasal mucosa boosts systemic allergen-specific IgE production. Intranasal corticosteroids (INCS) represent a first line treatment of allergic rhinitis but their effects on this boost of allergen-specific IgE production are unclear.
The simultaneous occurrence of metabolic syndrome and excessive daytime sleepiness are very common in obstructive sleep apnea (OSA) patients. Both conditions, if present in OSA, have been reported to be associated with inflammation and disruption of oxidative stress balance that impair the cardiovascular system. To verify the impact of daytime sleepiness on inflammatory and oxidative stress markers, we evaluated OSA patients without significant metabolic disturbance.