June 19, 2018

Prevalence of food allergens sensitization and food allergies in a group of allergic Honduran children

Open Access
Allergy, Asthma & Clinical Immunology
  • Victoria Alejandra Gonzales-GonzálezEmail author,
  • Adolfo Martin Díaz,
  • Karla Fernández and
  • María Félix Rivera
Allergy, Asthma & Clinical Immunology201814:23
Abstract
Background
Food allergy is a public health problem that has increased in the last decade. Despite the increasing rates in children, quality data on the burden of these diseases is lacking particularly in developing countries. Honduras has no studies in pediatric patients.

Earlier smoking after waking and the risk of asthma: a cross-sectional study using NHANES data

Open Access
Open Peer Review
BMC Pulmonary Medicine
BMC Pulmonary Medicine201818:102
Abstract
Background
Recent research shows that nicotine dependence conveys additional health risks above and beyond smoking behavior. The current study examines whether smoking within 5 min of waking, an indicator of nicotine dependence, is independently associated with asthma outcomes.

June 17, 2018

Fluticasone furoate/Vilanterol 92/22 μg once-a-day vs Beclomethasone dipropionate/Formoterol 100/6 μg b.I.D.: a 12-month comparison of outcomes in mild-to-moderate asthma

Open Access
  • Roberto W. Dal NegroEmail author,
  • Luca Bonadiman and
  • Paola Turco
Multidisciplinary Respiratory Medicine201813:18
Abstract
Background
Bronchial asthma is an inflammatory disease of the airways. Beclomethasone dipropionate/Formoterol (BDP/F) and Fluticasone furoate/Vilanterol (FF/V) are two of the most effective LABA/ICS combinations for managing persistent bronchial asthma.

June 13, 2018

The impact of cold on the respiratory tract and its consequences to respiratory health

Open Access
Clinical and Translational Allergy
Clinical and Translational Allergy20188:20
Abstract
The increasing use, and sometimes the abuse, particularly in industrialized countries of air conditioning at home, in car, hotel and shopping centres has highlighted new emerging public health issues, resulting from exposure of the airways to cool air or, more properly, resulting from sudden temperature changes.

June 12, 2018

Case report presenting the diagnostic challenges in a patient with recurrent acquired angioedema, antiphospholipid antibodies and undetectable C2 levels

Open Access
  • Arturo J. BonninEmail author,
  • Charles DeBrosse,
  • Terri Moncrief and
  • G. Wendell Richmond
Allergy, Asthma & Clinical Immunology201814:24
Abstract
Background
Angioedema secondary to acquired C1 inhibitor deficiency (AAE) is a rare disease. It usually is associated with lymphoproliferative disorders. We present a case of AAE in a patient with antiphospholipid syndrome (APS), a non-Hodgkin lymphoproliferative disorder (NHL) with undetectable levels of C2, C4, and an undetectable CH50. The co-existence of AAE, APS, and NHL, with an undetectable C2 level, to the best of our knowledge, has never before reported together in the same patient.

May 20, 2018

Anaesthesia, Surgery and Life-Threatening Allergic Reaction

NAP6 Report

Anaesthesia, Surgery and Life-Threatening Allergic Reactions

Report and findings of the Royal College of Anaesthetists' 6th National Audit Project


NAP6: Perioperative Anaphylaxis is the largest ever prospective study of anaphylaxis related to anaesthesia and surgery.
The full NAP6 Report is available in full as a single PDF, or as individual chapters below.
Some key findings of NAP6 are summarised on the NAP6 Infographic.
 NAP6 Infographic.pdf (718 KB)

Full Report

 NAP6-REPORT-2018 FINAL.pdf (11.75 MB)

May 15, 2018

Recent Advances in Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms

Journal of Immunology Research
Volume 2018, Article ID 5163129, 10 pages
https://doi.org/10.1155/2018/5163129
Review Article
Department of Dermatology, Showa University School of Medicine, Tokyo, Japan
Correspondence should be addressed to Hideaki Watanabehwatanabe@med.showa-u.ac.jp
Copyright © 2018 Hideaki Watanabe. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Drug-induced hypersensitivity syndrome (DIHS), also termed as drug reaction with eosinophilia and systemic symptoms (DRESS), is a multiorgan systemic reaction characterized by a close relationship with the reactivation of herpes virus. Published data has demonstrated that among patients with DIHS/DRESS, 75–95% have leukocytosis, 18.2–90% show atypical lymphocytes, 52–95% have eosinophilia, and 75–100% have hepatic abnormalities. Histologically, eosinophils were observed less frequently than we expected (20%). The mainstay of DIHS/DRESS treatment is a moderate dose of systemic corticosteroids, followed by gradual dose reduction.

The Microbiome and Risk for Atherosclerosis

Hot new areas of biomedicine sometimes generate cool skepticism. Little more than a decade ago, investigators proposed that the gut microbiome might be contributing to obesity. Since then, the microbiome has been linked to numerous major diseases, including atherosclerosis, although some have been skeptical about this association.

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