January 26, 2015

Differences in the clinical and radiological characteristics of lung-involved toxocariasis between toxocariasis with eosinophilia and those without eosinophilia

Authors: Bo Mi Park, Sang Ok Jeong, Hee Sun Park, Sung Soo Jung, Sun Young 
Kim, Ju Ock Kim, Jeong Eun Lee

Abstract

Background: Previously, most studies did not discuss about the characteristics of lung-involved toxocariasis without eosinophilia. However, the patients are not always accompanied by eosinophilia, so it is necessary to learn about the clinical and radiologic features that may predict pulmonary toxocariasis without eosinophilia.

Microbial contamination of domiciliary nebulisers and clinical implications in chronic obstructive pulmonary disease

  1. R J Shiner1
  1. 1Department of Respiratory MedicineImperial College Healthcare NHS Trust, Hammersmith HospitalLondon, UK
  2. 2Department of MicrobiologyHammersmith HospitalLondon, UK
  3. 3Central London Community Healthcare NHS Trust (CLCH), Charing Cross HospitalLondon, UK
  4. 4NHLI, Department of Cardiothoracic SurgeryHammersmith Hospital, Imperial CollegeLondon, UK

Abstract
Background and purpose Domiciliary nebulisers are widely used in chronic obstructive pulmonary disease (COPD) but nebuliser cleaning practice has not been assessed in patients with COPD who are often elderly and may have severe disease and multiple comorbidities. We aimed to evaluate microbial contamination of home nebulisers used by patients with COPD.

Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement






Research

Open AccessHighly Accessed

David Moher1*Larissa Shamseer1Mike Clarke2Davina Ghersi3Alessandro Liberati,Mark Petticrew4Paul Shekelle5Lesley A Stewart6 and PRISMA-P Group

Abstract


Systematic reviews should build on a protocol that describes the rationale, hypothesis, and planned methods of the review; few reviews report whether a protocol exists.

Removal of peanut allergen Ara h 1 from common hospital surfaces, toys and books using standard cleaning methods


Research

Published: 23 January 2015
Open AccessWade TA WatsonAnnMarie Woodrow and Andrew W Stadnyk

Allergy, Asthma & Clinical Immunology 2015, 11:4  doi:10.1186/s13223-015-0069-x

Abstract (provisional)

Background
In children, a diagnosis of peanut allergy causes concern about accidental exposure because even small amounts of peanut protein could trigger an allergic reaction.

January 24, 2015

The linkage of allergic rhinitis and obstructive sleep apnea

The linkage of allergic rhinitis and obstructive sleep apnea

Naricha Chirakalwasan, Kiat Ruxrungtham

Abstract


Rhinitis can be divided into allergic and non-allergic rhinitis. Rhinitis, particularly allergic rhinitis, has been shown to be associated with obstructive sleep apnea; a condition characterized by repetitive upper airway obstruction during sleep.

Impact of a countywide smoke-free workplace law on emergency department visits for respiratory diseases: a retrospective cohort study

Research article


Open AccessIvana T CroghanJon O EbbertJames T HaysDarrell R SchroederAlanna M Chamberlain,VĂ©ronique L Roger and Richard D Hurt

Abstract (provisional)
Background
With the goal of reducing exposure to secondhand smoke, the state of Minnesota (MN), enacted a smoke-free law (i.e., Freedom to Breathe Act) in all workplaces, restaurants, and bars in 2007. This retrospective cohort study analyzes emergency department (ED) visits in Olmsted County, MN, for chronic obstructive pulmonary disease (COPD) and asthma over a five-year period to assess changes after enactment of the smoke-free law.

Successful Desensitization of a Patient with Rituximab Hypersensitivity

Case Reports in Immunology
Volume 2015 (2015), Article ID 524507, 4 pages
http://dx.doi.org/10.1155/2015/524507
Case Report
1Department of Hematology, Ankara University, Cebeci, 06590 Ankara, Turkey
2Department of Pulmonary Medicine, Immunology and Allergy Clinic, Ankara University, Cebeci, 06590 Ankara, Turkey
Received 8 November 2014; Revised 1 January 2015; Accepted 1 January 2015
Academic Editor: Ahmad M. Mansour
Copyright © 2015 Pinar Ataca et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Rituximab is a monoclonal antibody which targets CD20 in B cells that is used for the treatment of CD20 positive oncologic and hematologic malignancies. Rituximab causes hypersensitivity reactions during infusions. The delay of treatment or loss of a highly efficient drug can be prevented by rapid drug desensitization method in patients who are allergic to rituximab. We report a low grade B cell non-Hodgkin lymphoma patient with rituximab hypersensitivity successfully treated with rapid drug desensitization. In experienced centers, drug desensitization is a novel modality to break through in case of hypersensitivity that should be considered.

Health economic comparison of SLIT allergen and SCIT allergoid immunotherapy in patients with seasonal grass-allergic rhinoconjunctivitis in Germany


Research
Open Access


Bram G Verheggen1*Kirsten Y Westerhout1Carl H Schreder2 and Matthias Augustin3

Abstract (provisional)

Background
Allergoids are chemically modified allergen extracts administered to reduce allergenicity and to maintain immunogenicity. Oralair (the 5-grass tablet) is a sublingual native grass allergen tablet for pre- and co-seasonal treatment. Based on a literature review, meta-analysis, and cost-effectiveness analysis the relative effects and costs of the 5-grass tablet versus a mix of subcutaneous allergoid compounds for grass pollen allergic rhinoconjunctivitis were assessed.

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