Autoimmune Diseases - Contributing Factors, Specific Cases of Autoimmune Diseases, and Stem Cell and Other Therapies

Edited by James Chan, ISBN 978-953-51-0693-7, Hard cover, 392 pages, Publisher: InTech, Published: July 25, 2012 under CC BY 3.0 license, in subject Immunology, Allergology and Rheumatology

DOI: 10.5772/2896

Autoimmune disease represents a group of more than 60 different chronic autoimmune diseases that affect approximately 6% of the population. Autoimmune diseases arise when ones immune system actively targets and destroys self tissue resulting in clinical disease with prime examples such as Lupus and Type 1 diabetes. The immune system is designed to protect us from foreign pathogens such as viruses and bacteria. However, during the process of generating immune cells for this purpose, as a negative consequence, self-reactive immune cells are also generated. This book aims to present the latest knowledge and insights regarding the different contributing factors and their interplay, discussions on several autoimmune diseases and their case studies, and therapeutic treatments, including stem cell, for autoimmune diseases.

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BOOK CONTENTS

• Chapter 1  Current Theories for Multiple Sclerosis Pathogenesis and Treatmentby Marcus Muller, Rachael Terry, Stephen D. Miller and Daniel R. Getts
• Chapter 2  Immunologic and Genetic Factors in Type 1 Diabetes Mellitusby Ahmad Massoud and Amir Hossein Massoud
• Chapter 3  Balancing pro- and anti-inflammatory CD4+ T helper cells in the intestineby Nicola Gagliani and Samuel Huber
• Chapter 4  T cell metabolism in autoimmune diseasesby Dan Li, Miranda Piccioni, Zhimei Gao, Chen Chen, Zuojia Chen, Jia Nie, Zhao Shan, Yangyang Li, Andy Tsun and Bin Li
• Chapter 5  Apoptosis and Autoimmune Disordersby Reginald Halaby
• Chapter 6  Immune Complex Deposits as a Characteristic Feature of Mercury-Induced SLE-Like Autoimmune Process in Inbred and Outbred Miceby Alla Arefieva, Marina Krasilshchikova and Olga Zatsepina
• Chapter 7  Celiac And Inflammatory Bowel Diseases In Children With Primary Humoral Immunodeficiencyby Pituch-Noworolska and Katarzyna Zwonarz
• Chapter 8  Central Nervous System Resident Cells in Neuroinflammation: A Brave New World.by J.P.S. Peron, D. Oliveira, W. N. Brandão, A. Fickinger, A. P. Ligeiro de Oliveira, L. V. Rizzo and N.O.S. Câmara
• Chapter 9  Autoimmune Encephalitis in Rural Central Illinoisby Reuben Mari Valenzuela, Paayal Patel and Jorge C. Kattah
• Chapter 10  The Role of the Antigen GAD 65 in Diabetes Mellitus Type 1: A Molecular Analysisby Marco Wiltgen and Gernot Tilz
• Chapter 11  New Therapeutic Challenges in Autoimmune Diseasesby Eun Wha Choi
• Chapter 12  Stem Cell Therapies for Type I Diabetesby Jesus Ciriza and Jennifer Manilay
• Chapter 13  Stem Cell-Based Cellular Therapy in Rheumatoid Arthritisby Rizwanul Haque, Fengyang Lei, Xiaofang Xiong and Jianxun Song
• Chapter 14  Biologic Treatment in Rheumatoid Arthritisby Katerina Chatzidionysiou
• Chapter 15  Biologic Therapy in Patients with Juvenile Idiopathic Arthritis – A Unique Single Centre Experience at the Scientific-Research Pediatric Centre in the Russian Federationby A.A. Baranov, E.I. Alexeeva, L.S. Namazova-Baranova, T.M. Bzarova, S.I. Valiyeva, R.V. Denisova, K.B. Isayeva, A.M. Chomakhidze, E.G. Chistyakova, T.V. Sleptsova, E.V. Mitenko, E.I. Zelikovich, G.V. Kurilenko, E.L. Semikina, A.V. Anikin, A.M. Stepanchenko, N.I. Taybulatov, A.V. Starikova, I.V. Dvoryakovskiy and M.V. Ryazanov
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  Published online: 25 July, 2012
  Published in print edition: July, 2012