May 15, 2013

Henoch Schonlein Purpura in children: clinical analysis of 120 cases


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Afr Health Sci. 2013 March; 13(1): 94–99.
PMCID: PMC3645106

Henoch Schonlein Purpura in children: clinical analysis of 120 cases

O Chen,1,2 XB Zhu,1 P Ren,5 YB Wang,3 RP Sun,1 and DE Wei4

Abstract

Background

Henoch Schonlein Purpura (HSP) is a systemic vasculitic disease which is common in children. It is very important to understand the clinical features of this disease for doctors and nurses.

Objectives

To study the clinical characteristics of HSP in children.

Methods

Collect the clinical data of the HSP children, and analyze the clinical characteristics of these HSP patients.

Results

The ratio of M:F was 1.9:1. The mean age was 6.6 ± 1.6 years. The typical onset seasons were spring, winter and autumn. Infection and food allergy were the main etiological factors. The first symptom was skin purpura and these purpura mainly concentrated the lower extremities and buttocks. The dominant digestive clinical features were abdominal pains and vomiting. The knee joint and ankle joint were most frequently affected. The typical kidney symptoms were microscopic hematuria and albuminuria. An increased ESR was reported in 68 patients (56.7%). Serum C3 decreased in 13 cases (10.8%). ASO titer was higher in 57 children (47.5%).

Conclusion

There were gender, season and area differences for the HSP patients. The etiological factors were diverse. HSP patients could have various clinical symptoms and rare complications.
Keywords: Henoch Schonlein Purpura, Children

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