Autoimmune Diseases
Volume 2013 (2013), Article ID 842673, 7 pages
http://dx.doi.org/10.1155/2013/842673
Clinical Study
Jelena Paovic,1 Predrag Paovic,1 and Vojislav Sredovic2
1Department of Ophthalmology, University Clinical Center, Pasterova 2, 11000 Belgrade, Serbia
2Uvea Centar, Center for Diagnostic and Treatment of Uveitis, Kneza od Semberije 14, 11000 Belgrade, Serbia
2Uvea Centar, Center for Diagnostic and Treatment of Uveitis, Kneza od Semberije 14, 11000 Belgrade, Serbia
Received 8 June 2013; Accepted 30 July 2013
Academic Editor: Hiroshi Ikegami
Copyright © 2013 Jelena Paovic et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
The aim of this study was to analyze ocular manifestations, their complications, and treatment in a sample of 40 patients with confirmed Behcet’s disease. Results. Serofibrinous iridocyclitis was the most common form of uveitis (60%). Retinal periphlebitis manifested in 92.5% of cases, and periphlebitis in conjunction with periarteritis was diagnosed in 72.5% of cases. Macular edema was the most frequent complication on the posterior segment (60%) and it correlated with periphlebitis () and periphlebitis associated with periarteritis (). Cyclosporine A and corticosteroids were used in the majority of cases (67%). Following six months of therapy, a significant improvement of visual acuity occurred in patients with initial visual acuity >0.5 on both eyes. Level of visual acuity before and after treatment had a strong significant correlation coefficient with various ocular complications. Previously proven significant increase of visual acuity in patients with macular edema depicts effectiveness of treatment in these types of ocular manifestations of Behcet’s disease. Conclusions. Significant improvement of visual acuity occurred in patients with initial visual acuity >0.5 on both eyes. The highest increase in visual acuity was achieved by laser photocoagulation in combination with triamcinolone acetonide .
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