- Mediators Inflamm
- v.2014; 2014
- PMC4009151
Mediators Inflamm. 2014; 2014: 207345.
Published online Apr 13, 2014. doi: 10.1155/2014/207345
PMCID: PMC4009151
Actions of Allergens and Mediators in Allergy
It has long been recognized that allergic inflammation is the fundamental pathological changes of allergy. Soluble allergens, specific IgE (sIgE), and mast cells or basophils are three key factors of allergy, representing causative factors, messenger, and primary effector cells, respectively. Eosinophils and neutrophils are known as secondary effector cells. In recent years, varieties of novel allergens and molecules involved in the allergic inflammation have been discovered, which makes the current understanding of the mechanisms of allergy even more confusing. We still have long way to go before the clear picture of pathogenesis of allergic inflammation can be accomplished, but our continuous and hard effort will help us to finally reach our destination drawing a complete picture of allergy. In this respect, this special issue will add a few new points in the picture of allergic inflammation....
No comments:
Post a Comment