- NIHPA Author Manuscripts
- PMC3797257
Matern Child Health J. Author manuscript; available in PMC Nov 3, 2013.
Published in final edited form as:
PMCID: PMC3797257
NIHMSID: NIHMS487202
Craig Hansen, PhD,1 Peter Joski, MSPH,1 Heather C. Freiman, MSPH,1 Susan Andrade, ScD,2 Sengwee Toh, ScD,3Sascha Dublin, MD, PhD,4 T. Craig Cheetham, PharmD, MS,5 William O. Cooper, MD, MPH,6 Pamala A. Pawloski, PharmD,7 De-Kun Li, MD, PhD,8 Sarah J. Beaton,9 Pamela E. Scott, PhD, MA,10 Tarek Hammad, MD PhD,10 andRobert Davis, MPH1
The publisher's final edited version of this article is available at Matern Child Health J
Abstract
Background
Asthma is one of the most common chronic diseases in women of reproductive age, occurring in up to 8% of pregnancies.
Objective
Assess the prevalence of asthma medication use during pregnancy in a large diverse cohort.
Methods
We identified women aged 15 to 45 years who delivered a live born infant between 2001 and 2007 across 11 U.S. health plans within the Medication Exposure in Pregnancy Risk Evaluation Program (MEPREP). Using health plans’ administrative and claims data, and birth certificate data, we identified deliveries for which women filled asthma medications from 90 days before pregnancy through delivery. Prevalence (%) was calculated for asthma diagnosis and medication dispensing.
Results
There were 586,276 infants from 575,632 eligible deliveries in the MEPREP cohort. Asthma prevalence among mothers was 6.7%, increasing from 5.5% in 2001 to 7.8% in 2007. A total of 9.7% (n=55,914) of women were dispensed asthma medications during pregnancy. The overall prevalence of maintenance-only medication, rescue-only medication, and combined maintenance and rescue medication was 0.6%, 6.7%, and 2.4% respectively. The prevalence of maintenance-only use doubled during the study period from 0.4% to 0.8%, while rescue-only use decreased from 7.4% to 5.8%.
Conclusions
In this large population-based pregnancy cohort, the prevalence of asthma diagnoses increased over time. The dispensing of maintenance-only medication increased over time, while rescue-only medication dispensing decreased over time.
Keywords: Asthma, Pregnancy, Medication, Prevalence
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