September 19, 2014

The effects of GERD dyspepsia and rhinosinusitis on asthma

Tamotsu Ishizuka,1,2 Takeshi Hisada,2 Yosuke Kamide,2 Haruka Aoki,2 Kaori Seki,2 Chisato Honjo,1 Hiroyuki Sakai,Maiko Kadowaki,1 Yukihiro Umeda,1 Miwa Morikawa,1 Masaki Anzai,1Shingo Ameshima,1 Takeshi Ishizaki,1 Kunio Dobashi,2 Masanobu Yamada,2 Motoyasu Kusano3
1Third Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Fukui,2Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, 3Department of Endoscopy and Endoscopic Surgery, Gunma University Hospital, Maebashi, Japan

September 16, 2014

Gaining the Upper Hand on Pulmonary Drug Delivery

Journal of Pharmacovigilance

Open 
J Pharmacovigil. Author manuscript; available in PMC Aug 11, 2014.
Published in final edited form as:
J Pharmacovigil. Mar 1, 2014; 2(1): 118.
Published online Mar 1, 2014. doi:  10.4172/2329-6887.1000118
PMCID: PMC4128189
NIHMSID: NIHMS593165

Maternal immunization with ovalbumin or Dermatophagoides pteronyssinus has opposing effects on FcγRIIb expression on offspring B cells

Short report

Open Access

Aline Aparecida de Lima LiraMarília Garcia de OliveiraLuana Mendonça de Oliveira,Alberto José da Silva DuarteMaria Notomi Sato and Jefferson Russo Victor*
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September 15, 2014

Molecular Determinants Responsible for Sedative and Non-sedative Properties of Histamine H1–Receptor Antagonists

Journal of Pharmacological SciencesVol. 124 (2014) No. 2 p. 160-168

Language: 


http://dx.doi.org/10.1254/jphs.13169FP
 
DN/JST.JSTAGE/jphs/13169FP
Full Paper

Cytotoxic proteins and therapeutic targets in severe cutaneous adverse reactions

Review

Cytotoxic Proteins and Therapeutic Targets in Severe Cutaneous Adverse Reactions

 1email and  1,2,email

Received: 28 November 2013; in revised form: 20 December 2013 / Accepted: 27 December 2013 / Published: 3 January 2014
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Lactobacilli regulate Staphylococcus aureus 161:2-induced pro-inflammatory T-cell responses in vitro


Department of Molecular Biosciences, the Wenner-Gren Institute, Stockholm University, Stockholm, Sweden.

Exogenous interleukin-10 alleviates allergic inflammation but inhibits local interleukin-10 expression in a mouse allergic rhinitis model.

Research article

Open Access

Shui-Bin Wang13Yu-Qin Deng1Jie Ren1Bo-Kui Xiao1Zheng Liu2* and Ze-Zhang Tao1*
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Twenty-first century mast cell stabilizers

Impact of endobronchial allergen provocation on macrophage phenotype in asthmatics

Research article

Open Access

Carla Winkler12Lena Witte12Natali Moraw2Conny Faulenbach2Meike Müller2Olaf Holz23Frank Schaumann2 and Jens M Hohlfeld123*

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Depigmented-polymerised allergoids favour regulatory over effector T cells: enhancement by 1α, 25-dihydroxyvitamin D3

Research article

Zoe L Urry1David F Richards1Cheryl Black1Maria Morales2Jerónimo Carnés2,Catherine M Hawrylowicz1* and Douglas S Robinson3*

1Department of Allergy and Asthma, MRC and Asthma UK Centre for Mechanisms of Allergic Asthma, Guy’s Campus, King’s College London, London, UK
2Department of Research and Development, Laboratorios Leti, Tres Cantos, Madrid, Spain
3Leukocyte Biology Section, MRC and Asthma UK Centre for Mechanisms of Allergic Asthma, NHLI, Imperial College London, London, UK
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The electronic version of this article is the complete one and can be found online at:http://www.biomedcentral.com/1471-2172/15/21

Received:30 October 2013
Accepted:16 May 2014
Published:29 May 2014
© 2014 Urry et al.; licensee BioMed Central Ltd. 
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

September 14, 2014

A Long-Term Risk? Prenatal POPs Exposure and Asthma in Young Adults


Lindsey Konkel is a Worcester, MA–based journalist who reports on science, health, and the environment. She is an editor for Environmental Health News and The Daily Climate.
About This Article open

“The focus in immunotoxicity studies has often been on immunologic intermediates, such as immune cell counts. This study is unique in that it looks at a long-term clinically relevant outcome,” says Todd Jusko, an environmental epidemiologist at the University of Rochester, who was not involved in the study.
lthough previous research has suggested that prenatal exposures to persistent organic pollutants (POPs) may be harmful to a child’s developing immune system,1 few studies have investigated long-term outcomes in this regard. Findings reported in this issue of EHP provide evidence that exposure to certain POPs in the womb may be associated with an increased risk of developing asthma that persists into young adulthood.2