October 30, 2014

Diagnosis and management of food allergies: new and emerging options: a systematic review

Authors Andrew W O'Keefe,1,2 Sarah De Schryver,1 Jennifer Mill,3 Christopher Mill,3 Alizee Dery,1 Moshe Ben-Shoshan1
Published Date October 2014 Volume 2014:7 Pages 141—164
Received 15 July 2014Accepted 19 August 2014, Published 24 October 2014
Approved for publication by Dr Linda Cox

SLIT: indications, follow-up, and management

I Dávila1, A Navarro2, J Domínguez-Ortega3, A Alonso4, D Antolín-Amérigo5, MC Diéguez6, E González-Mancebo7, C Martín8, C Martínez9, B Núñez10, N Prior11, M Reche12, A Rosado13, J Ruiz-Hornillos14, A Sansosti15, M Torrecillas16, MJ Jerez17; QUASAR Group (QUality in the Administration of SLIT in Allergic Rhinitis)

October 28, 2014

Histamine H4 receptor: A Novel Drug Target For Immunoregulation and Inflammation. Open Access Book



Aims and Scope

H4R is the newest member of the histamine receptor family, which was discovered about twelve years ago. It is considered a very promising drug target. The effort to improve the pharmacokinetic properties of the currently available H4R ligands is reflected in a steadily growing number of scientific publications and patent applications. Preclinical data strongly confirms the need for novel potent H4R ligands to explore their therapeutic value in allergy, inflammation, autoimmune disorders, and possibly, cancer.
Readers will be provided with extensive knowledge on histamine metabolism, as well as cellular histamine transport, storage and release, effects of histamine and histamine receptor ligands, with particular attention to the H4R, on inflammatory cells including mast cells, basophils, eosinophils, neutrophils, macrophages, dendritic cells, and T cells. The present knowledge on the regulatory role of histamine and the therapeutic exploitation of histamine receptor ligands in atopic diseases, with emphasis on human and animal models of asthma, allergic dermatitis and pruritus are discussed.

Developmental profiles of eczema, wheeze, and rhinitis: two population-based birth cohort studies



October 27, 2014

Drug Allergy: Diagnosis and Management of Drug Allergy in Adults, Children and Young People

NICE Clinical Guidelines, No. 183

National Clinical Guideline Centre (UK).

A Rapid Method of Detecting Autoantibody against FcεRIα for Chronic Spontaneous Urticaria


PLoS One. 2014; 9(10): e109565.
Published online Oct 15, 2014. doi:  10.1371/journal.pone.0109565
PMCID: PMC4198112

The influence of trigger factors on hereditary angioedema due to C1-inhibitor deficiency

Research

Open AccessZsuzsanna ZotterDorottya CsukaErika SzabóIbolya CzallerZsuzsanna Nébenführer,György TemesszentandrásiGeorge FustLilian Varga and Henriette Farkas*


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Orphanet Journal of Rare Diseases 2014, 9:44  doi:10.1186/1750-1172-9-44

Health impact assessment of air pollution in Valladolid, Spain


BMJ Open 4:e005999 doi:10.1136/bmjopen-2014-005999
  • Public health

Allergy-related evidences in relation to serum IgE: data from the China state key laboratory of respiratory disease, 2008-2013


Swyer-James syndrome associated with asthma and a giant bulla

Respirology Case Reports

  • Hidenao Kayawake1,2,*
  • Hiroaki Sakai2,
  • Hisako Matsumoto3 and
  • Hiroshi Date2
  • October 24, 2014

    Lesson of the month: extrinsic allergic (bronchiolo)alveolitis and metal working fluids

    • Chest clinic
    • Case based discussion

    Serum immunoglobulins in 28 adults with autoimmune sensorineural hearing loss: increased prevalence of subnormal immunoglobulin G1 and immunoglobulin G3

    Research article

    Open Access

    Luigi F Bertoli12Dennis G Pappas13J Clayborn Barton4 and James C Barton145*

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    Non-emphysematous chronic obstructive pulmonary disease is associated with diabetes mellitus

    Research article

    Open Access

    Craig P HershBarry J MakeDavid A LynchR Graham BarrRussell P BowlerPeter MA CalverleyPeter J CastaldiMichael H ChoHarvey O CoxsonDawn L DeMeoMarilyn G ForemanMeiLan K HanBenjamin J HarshfieldJohn E HokansonSharon LutzJoe W RamsdellElizabeth A ReganStephen I RennardJoyce D SchroederFrank C Sciurba,Robert M SteinerRuth Tal-SingerEdwin JR van BeekEdwin K Silverman and James D Crapo
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    HLA-E: A Novel Player for Histocompatibility

    Journal of Immunology Research
    Volume 2014 (2014), Article ID 352160, 7 pages
    http://dx.doi.org/10.1155/2014/352160
    Review Article