- Johan Nilsson Sommar1,
- Alexandra Ek2,
- Roelinde Middelveld3,4,
- Anders Bjerg5,
- Sven-Erik Dahlén2,
- Christer Janson6 and
- Bertil Forsberg1
+Author Affiliations
- Correspondence toDr Johan Nilsson Sommar; johan.n.sommar@envmed.umu.se
January 18, 2015
Quality of life in relation to the traffic pollution indicators NO2 and NOx: results from the Swedish GA2LEN survey
January 16, 2015
Fifty years of allergy: 1965–2015
Journal of Paediatrics and Child Health
Abstract
The last 50 years in allergy could almost be considered the first 50 years. Over this time period, we have witnessed the emergence of allergy as a subspecialty, have seen and continue to observe a tremendous change in prevalence of allergic disease and have gained insight into the mechanisms that underlie allergic predisposition and disease manifestation. We have improved the care of children with many forms of allergic disease and now sit poised to be able to alter the natural history of allergic disease with the use of specific immunotherapy. There is much left to do in the next 50 years including understanding what underlies both the predisposition to atopic disease and its natural resolution and identifying the environmental cofactors involved in the ‘allergic epidemic’ and therefore targets for effective primary prevention.
Evidence-based medicine: What has happened in the past 50 years?
Article first published online: 24 DEC 2014
Abstract
Although the phrase ‘evidence-based medicine’ (EBM) was used for the first time in the medical literature less than 25 years ago, the history of EBM goes back for centuries. What is remarkable is how popular and how globally accepted the EBM movement has become in such a short time. Many famous, past clinicians have played major roles in the disciplines that preceded EBM, particularly ‘clinical epidemiology’. It soon became clear to the early EBM champions that ‘evidence’ was only part of the clinical decision-making process. Consequently, both clinical expertise and the patient's values and preferences were rapidly incorporated into the concept we now know as ‘EBM’. The current need for high-quality, easily accessible ‘evidence-based summaries’ for busy clinicians is now apparent, as traditional EBM requires both considerable time and skill. Consequently, there is a progressive move away from the primary literature (such as randomised controlled trials) to systematic reviews and other ‘evidence-based summaries’. The future of EBM will almost certainly involve widespread utilisation of ‘clinical (computer)-based decision support systems’.
January 15, 2015
High body mass index and allergies in schoolchildren: the French six cities study
- Respiratory epidemiology
- Danielle Saadeh1,7,
- Pascale Salameh1,
- Denis Caillaud2,
- Denis Charpin3,
- Frédéric de Blay4,
- Christine Kopferschmitt4,
- François Lavaud5,
- Isabella Annesi-Maesano6,
- Isabelle Baldi7 and
- Chantal Raherison7,8
+Author Affiliations
- Correspondence toDanielle Saadeh; daniellesaadeh@hotmail.com
- Received 23 July 2014
- Accepted 3 October 2014
- Published 24 December 2014
Abstract
Background The prevalence of allergic diseases such as asthma, allergic rhinitis and atopic dermatitis is increasing rapidly worldwide, especially among children and in western countries. This coincides with an increase in body mass index (BMI), which might be a major risk factor for atopic diseases.
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