NATURE COMMUNICATIONS | ARTICLE OPEN
- Received
- Accepted
- Published
October 2, 2015
October 1, 2015
Atopic dermatitis: A cross-sectional (descriptive) study of 100 cases
| E-IJD ORIGINAL ARTICLE | ||||
| Year : 2015 | Volume : 60 | Issue : 5 | Page : 519 | ||||
| Virendra N Sehgal1, Govind Srivastava2, Ashok K Aggarwal2, Deepti Saxena2, Kingshuk Chatterjee3, Ananta Khurana4 1 Dermato Venereology (Skin/VD) Center, Sehgal Nursing Home, Panchwati, Delhi, India 2 Skin Institute, School of Dermatology, Greater Kailash, New Delhi, India 3 Department of Dermatology, Bankura Sammilani Medical College, Bankura, West Bengal, India 4 Department of Dermatology, Dr RML hospital and Postgraduate Institute of Medical Education and research (PGIMER), New Delhi, India | ||||
Background: Atopic dermatitis is a distinct age-related clinical entity. Its etiopathogenesis is largely insubstantial. Nevertheless, it seems to be an outcome of interplay of maternal and inheritance, pregnancy/intrauterine and environmental factors. Besides, immune dysregulation, and nutritional supplements also play essential roles. Its diagnosis has been perpetuated by three or more major/minor criteria.
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September 30, 2015
Sublingual grass and ragweed immunotherapy: Clinical considerations—a PRACTALL consensus report
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Received: May 18, 2015; Received in revised form: June 25, 2015; Accepted: June 30, 2015; Published Online:September 11, 2015
Publication stage: In Press Corrected Proof
Article InfoAirways resistance and specific conductance for the diagnosis of obstructive airways diseases
Abstract
Background
The GINA asthma strategy report: what’s new for primary care?
Abstract
The Global Initiative for Asthma (GINA) was established in 1993 by the World Health Organization and National Heart Lung and Blood Institute to develop a global strategy for managing and preventing asthma. GINA reports, now funded independently through the sale of GINA products, have provided the foundation for many national guidelines. They are prepared by international experts from primary, secondary and tertiary care, and are annually updated following a review of evidence.
September 29, 2015
Interrelatedness between dysbiosis in the gut microbiota due to immunodeficiency and disease penetrance of colitis
Summary
The composition of the microbiome in health and disease has only recently become a major research focus. Although it is clear that an imbalance or dysbiosis in the microbiota is associated with disease, its interrelatedness to disease penetrance is largely unknown.
Inflammatory bowel disease (IBD) is an excellent disease in which to explore these questions because of the extensive genetic studies identifying disease susceptibility loci and the ability to easily sample the intestinal microbiota in IBD patients due to the accessibility of stool samples. In addition, mouse models of IBD have contributed to our understanding of the interrelatedness of the gut microbiota and genes associated with IBD. High risk for obstructive sleep apnea and other sleep disorders among overweight and obese pregnant women
Background
Obstructive sleep apnea (OSA), a common and serious disorder in which breathing repeatedly stops during sleep, is associated with excess weight and obesity. Little is known about the co-occurrence of OSA among pregnant women from low and middle-income countries.
Sleep Apnea Clinical Score, Berlin Questionnaire, or Epworth Sleepiness Scale: which is the best obstructive sleep apnea predictor in patients with COPD?
ORIGINAL RESEARCH
Anamelia Costa Faria, Cláudia Henrique da Costa, Rogério Rufino
Cardiopulmonology Department, State University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil
Introduction: The Sleep Apnea Clinical Score (SACS) and the Berlin Questionnaire (BQ) are used to predict the likelihood of obstructive sleep apnea (OSA). The Epworth Sleepiness Scale (ESS) is used to assess daytime sleepiness, a common OSA symptom. These clinical tools help prioritize individuals with the most severe illness regarding on whom polysomnography (PSG) should be performed. It is necessary to check the applicability of these tools in patients with chronic obstructive pulmonary disease (COPD). The aim of this study is to compare SACS, BQ, and ESS performance in patients with COPD.
Cardiopulmonology Department, State University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil
Introduction: The Sleep Apnea Clinical Score (SACS) and the Berlin Questionnaire (BQ) are used to predict the likelihood of obstructive sleep apnea (OSA). The Epworth Sleepiness Scale (ESS) is used to assess daytime sleepiness, a common OSA symptom. These clinical tools help prioritize individuals with the most severe illness regarding on whom polysomnography (PSG) should be performed. It is necessary to check the applicability of these tools in patients with chronic obstructive pulmonary disease (COPD). The aim of this study is to compare SACS, BQ, and ESS performance in patients with COPD.
Using magnetic resonance imaging to quantify the inflammatory response following allergen challenge in allergic rhinitis
2050-4527/asset/olbannerright.gif?v=1&s=8d9181e6d690dd839ba2cf6baf527480ed8c5766)
Immunity, Inflammation and Disease
Abstract
Current rhinometric and flow assessments measure nasal patency and are often poorly correlated with rhinitis symptoms. To evaluate magnetic resonance imaging (MRI) as a new method to measure inflammatory changes in nasal and sinus mucosa following nasal allergen challenge.
September 23, 2015
Lactobacillus rhamnosus GG-supplemented formula expands butyrate-producing bacterial strains in food allergic infants
OPEN
Roberto Berni Canani1,8, Naseer Sangwan2,8, Andrew T Stefka3,8, Rita Nocerino1, Lorella Paparo1, Rosita Aitoro1, Antonio Calignano4, Aly A Khan5, Jack A Gilbert2,6,7and Cathryn R Nagler3
- 1Department of Translational Medical Science, Section of Pediatrics, European Laboratory for the Investigation of Food-Induced Diseases, University of Naples, Federico II, Naples, Italy
- 2Institute for Genomics and Systems Biology, Department of Biosciences, Argonne National Laboratory, Argonne, IL, USA
- 3Committee on Immunology and Department of Pathology, University of Chicago, Chicago, IL, USA
- 4Department of Pharmacy, University of Naples Federico II, Naples, Italy
- 5Toyota Technological Institute at Chicago, Chicago, IL, USA
- 6Department of Surgery, University of Chicago, Chicago, IL, USA
- 7Department of Ecology and Evolution, University of Chicago, Chicago, IL, USA
Abstract
Dietary intervention with extensively hydrolyzed casein formula supplemented with Lactobacillus rhamnosus GG (EHCF+LGG) accelerates tolerance acquisition in infants with cow’s milk allergy (CMA). We examined whether this effect is attributable, at least in part, to an influence on the gut microbiota. Fecal samples from healthy controls (n=20) and from CMA infants (n=19) before and after treatment with EHCF with (n=12) and without (n=7) supplementation with LGG were compared by 16S rRNA-based operational taxonomic unit clustering and oligotyping.
Sublingual Immunotherapy with a Five-Grass Pollen Tablet in Adult Patients with Allergic Rhinitis: An Open, Prospective, Noninterventional, Multicenter Study
BioMed Research InternationalVolume 2015 (2015), Article ID 584291, 11 pages
Research Article
Abstract
Background. Although the safety and efficacy of sublingual immunotherapy (SLIT) with a five-grass pollen tablet have been demonstrated in randomized clinical trials (RCTs), these outcomes must always be evaluated in real-life medical practice.
September 22, 2015
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