Titanium exposure and yellow nail syndrome

Ali Ataya

,

 Kristopher Kline

,

 Jessica Cope

,

 Hassan Alnuaimat

Publication stage: In Press Accepted Manuscript

Open Access

DOI: http://dx.doi.org/10.1016/j.rmcr.2015.10.002

Open access funded by the Author(s)

Article Info

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Abstract

Yellow nail syndrome is a rare disease of unclear etiology. We describe a patient who develops yellow nail syndrome, with primary nail and sinus manifestations, shortly after amalgam dental implants. A study of the patient's nail shedding showed elevated nail titanium levels. The patient had her dental implants removed and had complete resolution of her sinus symptoms with no change in her nail findings. Since the patient’s nail findings did not resolve we do not believe titanium exposure is a cause of her yellow nail syndrome but perhaps a possible relationship exists between titanium exposure and yellow nail syndrome that requires further studies.

The evaluation of the dust-related occupational respiratory disorders of dental laboratory technicians working in Denizli Province

ORIGINAL ARTICLE

Year : 2015  |  Volume : 10  |  Issue : 4  |  Page : 249-255

Belkis Yurdasal1, Nurgül Bozkurt2, Ali İhsan Bozkurt3, Özlem Yilmaz1 1 Oral Health Division Director, Denizli Health Directorate, Pamukkale University, Denizli, Turkey 2 Department of Pulmonology, Denizli State Hospital, Pamukkale University, Denizli, Turkey 3 Department of Public Health, Faculty of Medicine, Pamukkale University, Denizli, Turkey DOI: 10.4103/1817-1737.167073

Abstract   INTRODUCTION: Dental laboratory technicians (DLTs) get exposed to fibrinogen dusts that are very risky dusts in terms of health. In this study, respiration complaints, pneumoconiosis frequencies and working conditions of the dental technicians in Denizli were investigated.

Epinephrine auto-injector prescriptions to food-allergic patients in primary care in The Netherlands

Research

Jacquelien Saleh-Langenberg^12*, A. E. J. Dubois¹², F. Groenhof³, J. W. H. Kocks²³, T. van der Molen²³ and B. M. J. Flokstra-de Blok²³

Allergy, Asthma & Clinical Immunology 2015, 11:28  doi:10.1186/s13223-015-0094-9

Abstract

Background

The knowledge of general practitioner(s) (GPs) regarding food allergy and anaphylaxis and practices in the prescription of epinephrine auto-injector(s) (EAIs) among GPs has previously only been studied using questionnaires and hypothetical cases. Therefore, there are currently no data as to whether or not GPs prescribe EAIs to high risk food-allergic patients presenting to primary care practices. The aim of this study was therefore to describe and evaluate practice in EAI prescription by GPs to food-allergic patients in The Netherlands.

Sensitization to fungal allergens: Resolved and unresolved issues

October 2015Volume 64, Issue 4, Pages 321–331

Yuma Fukutomi

,

 Masami Taniguchi

Clinical Research Center for Allergy and Rheumatology, Sagamihara National Hospital, Kanagawa, Japan

Open Access

DOI: http://dx.doi.org/10.1016/j.alit.2015.05.007

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Open access funded by Japanese Society of Allergology

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Abstract

Exposure and sensitization to fungal allergens can promote the development and worsening of allergic diseases. Although numerous species of fungi have been associated with allergic diseases in the literature, the significance of fungi from the genera Alternaria, Cladosporium, Penicillium, Aspergillus, and Malasseziahas been well documented. However, it should be emphasized that the contribution of different fungal allergens to allergic diseases is not identical, but species-specific.

Latest developments in Allergic Rhinitis in Allergy for Clinicians and Researchers

Accepted Article (Accepted, unedited articles published online and citable. The final edited and typeset version of record will appear in future.)  DOI: 10.1111/all.12782

1. Chew Lip Ng and
2. De Yun Wang^*
3. 
   
4. Abstract
   Research efforts in allergic rhinitis has always been intense. Over the past 3 years, numerous breakthroughs in basic science and clinical research have been made, augmenting our understanding of this condition that afflicts a significant proportion of the global population.

Update on food allergy

Accepted Article (Accepted, unedited articles published online and citable. The final edited and typeset version of record will appear in future.)  DOI: 10.1111/all.12780

1. Annette Carrard¹, 
2. David Rizzuti²and
3. Christiane Sokollik^2,*

5. 1. 1. Abstract

         Food allergies are a global health issue with increasing prevalence. Allergic reactions can range from mild local symptoms to severe anaphylactic reactions. Immense progress has been made in diagnostic tools such as component-resolved diagnostics and its impact on risk stratification as well as in therapeutic approaches including biologicals.

Recurrent respiratory tract infections in children – analysis of immunological examinations

Agata Raniszewska, Elżbieta Górska, Iwona Kotuła, Anna Stelmaszczyk-Emmel, Katarzyna Popko, Olga Ciepiela

(Centr Eur J Immunol 2015; 40 (2): 167-173)

DOI (digital object identifier): 10.5114/ceji.2015.52830

 

Background: Paediatric respiratory tract infections are among the most common reasons for preschool and school absences and visits to physicians. The disease mainly involves the upper respiratory tract and is associated with fever, cough, sore throat, and running nose. Children with recurrent respiratory infections (RRI), which are defined as more than six serious diseases a year, are a difficult diagnostic challenge. The aim of this study was to assess immunological deviations in laboratory tests performed in children with RRI.

Twin Studies of Atopic Dermatitis: Interpretations and Applications in the Filaggrin Era

J Allergy (Cairo). 2015; 2015: 902359.doi:  10.1155/2015/902359PMCID: PMC4581550
Camilla Elmose 1 and Simon Francis Thomsen 1 , 2 , *

Author information ►

Abstract

Aim. The aim of this study was to conduct a systematic review of population-based twin studies of (a) the concordance and heritability of AD and (b) the relationship between AD and asthma and, furthermore, to reinterpret findings from previous twin studies in the light of the emerging knowledge about filaggrin and its role in the atopic march and provide suggestions for future research in this area. 

Attenuated Allergenic Activity of Ovomucoid After Electrolysis

Allergy Asthma Immunol Res > v.7(6); Nov 2015   Brief Communication  Open Access Jun Kido,1,2 and Tomoaki Matsumoto1,3,4 1Department of Pediatrics, Kumamoto Regional Medical Center, Kumamoto City, Kumamoto, Japan. 2Department of Pediatrics, Graduate School of Medical Sciences, Kumamoto University, Kumamoto City, Kumamoto, Japan. 3Department of Child Development, Kumamoto University Hospital, Kumamoto City, Kumamoto, Japan. 4Pediatric Division, Aso Spa Hospital, Aso City, Kumamoto, Japan. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Ovomucoid (OMC) is the most prominent allergen causing hen's egg allergy, containing disulfide (S-S) bonds that may be responsible for its allergic action. As S-S bonds may be reduced during electrolysis, this study was undertaken to evaluate modulation of the allergic action of OMC after electrolysis. Electrolysis was carried out for 1% OMC containing 1% sodium chloride for 30 minutes with a voltage difference of 90 V, 0.23 A (30 mA/cm2).

The role of IL-33 and mast cells in allergy and inflammation

Review

Rohit Saluja^134*, Mahejibin Khan², Martin K. Church¹ and Marcus Maurer^1*

Clinical and Translational Allergy 2015, 5:33  doi:10.1186/s13601-015-0076-5

Abstract

Interleukin-33 (IL-33) is a member of the interleukin-1 (IL-1) cytokine family. It is preferentially and constitutively expressed in different structural cells such as epithelial cells, endothelial cells, and smooth muscle cells. During necrosis of these cells (after tissue injury or cell damage), the IL-33 that is released may be recognized by different types of immune cells, such as eosinophils, basophils and, especially, mast cells.

AIT (allergen immunotherapy): a model for the “precision medicine”

Commentary

Giovanni Passalacqua^* and Giorgio Walter Canonica

Clinical and Molecular Allergy 2015, 13:24  doi:10.1186/s12948-015-0028-6

Abstract

The interpretation of medical approaches, especially therapy, evolved rapidly in the last century. Starting from the simple description of symptoms, we moved to the pathophysiological descriptions, to the evidence-based medicine, until the so-called “precision medicine”. This latter can be defined as a structural model aimed at customizing healthcare, with medical decisions/products tailored on an individual patient at a highly detailed level.

Angioedema induced by cardiovascular drugs: new players join old friends

Review Article

You have free access to this content

Allergy Volume 70, Issue 10, pages 1196–1200, October 2015

1. M. Bas¹, 
2. J. Greve², 
3. U. Strassen¹, 
4. F. Khosravani³, 
5. T. K. Hoffmann² and
6. G. Kojda^3,*

Abstract

During the last years, two new cardiovascular drug classes, namely inhibitors of DPP IV or neprilysin, have been developed. In both cases, there is clinical evidence for their potential to induce angioedema as known already from blockers of the renin–angiotensin–aldosterone system (RAAS).

Pathophysiological mechanisms of exercise-induced anaphylaxis: an EAACI position statement

Allergy Volume 70, Issue 10, pages 1212–1221, October 2015

L. Ansley^1,*, 

M. Bonini², 

L. Delgado³, 

S. Del Giacco⁴, 

G. Du Toit⁵, 

M. Khaitov⁶, 

M. Kurowski⁷, 

J. H. Hull⁸, 

A. Moreira³ and

P. J. Robson-Ansley¹

Abstract

This document is the result of a consensus on the mechanisms of exercise-induced anaphylaxis (EIAn), an unpredictable and potentially fatal syndrome. A multidisciplinary panel of experts including exercise physiologists, allergists, lung physicians, paediatricians and a biostatistician reached the given consensus.