November 2, 2015

A common language to assess allergic rhinitis control: results from a survey conducted during EAACI 2013 Congress

Research

Open Access

Peter W. Hellings12*Antonella Muraro3Wytske Fokkens2Joaquim Mullol4Claus Bachert5G. Walter Canonica6,David Price7Nikos Papadopoulos8Glenis Scadding9Gerd Rasp10Pascal Demoly11Ruth Murray12 and Jean Bousquet13141516
Abstract
Background
The concept of control is gaining importance in the field of allergic rhinitis (AR), with a visual analogue scale (VAS) score being a validated, easy and attractive tool to evaluate AR symptom control. The doctors’ perception of a VAS score as a good tool for evaluating AR symptom control is unknown, as is the level of AR control perceived by physicians who treat patients.

October 30, 2015

Structural similarities of human & mammalian lipocalins, and their function in innate immunity and allergy

      1. E Jensen-Jarolim, 
      2. Luis F Pacios, 
      3. R Bianchini, 
      4. G Hofstetter and
      5. F Roth-Walter
        1. Abstract

          Owners and their domestic animals via skin shedding and secretions, mutually exchange microbiomes, potential pathogens and innate immune molecules. Among the latter especially lipocalins are multifaceted: they may have an immunomodulatory function and, furthermore, they represent one of the most important animal allergen families.

The 2015 IUIS Phenotypic Classification for Primary Immunodeficiencies


 2015 Oct 7. [Epub ahead of print]

Open Access

  • Aziz Bousfiha, 
  • LeĂŻla Jeddane
  • Waleed AlHerz
  • Fatima Ailal
  • JeanLaurent Casanova
  • ,Talal Chatila
  • Mary Ellen Conley
  • Charlotte Cunningham‐Rundles
  • Amos Etzioni
  • Abstract

    There are now nearly 300 single-gene inborn errors of immunity underlying phenotypes as diverse as infection, malignancy, allergy, auto-immunity, and auto-inflammation. For each of these five categories, a growing variety of phenotypes are ascribed to Primary Immunodeficiency Diseases (PID), making PIDs a rapidly expanding field of medicine.

    From bronchiolitis guideline to practice: A critical care perspective

    James A Lin, Andranik Madikians, Division of Pediatric Critical Care Medicine, Department of Pediatrics, Mattel Children’s Hospital UCLA, University of California, Los Angeles, CA 90095, United States

    Acute viral bronchiolitis is a leading cause of admission to pediatric intensive care units, but research on the care of these critically ill infants has been limited. Pathology of viral bronchiolitis revealed respiratory obstruction due to intraluminal debris and edema of the airways and vasculature. This and clinical evidence suggest that airway clearance interventions such as hypertonic saline nebulizers and pulmonary toilet devices may be of benefit, particularly in situations of atelectasis associated with bronchiolitis.

    October 28, 2015

    Structural and functional rejuvenation of the aged brain by montelukast

    Nature Communications
     
    6,
     
    Article number:
     
    8466
     
    doi:10.1038/ncomms9466
    Received
     
    Accepted
     
    Published
     

    Abstract

    As human life expectancy has improved rapidly in industrialized societies, age-related cognitive impairment presents an increasing challenge.

    Timing and duration of omalizumab response in patients with chronic idiopathic/spontaneous urticaria

    Background
    Few data are available that describe response patterns in patients with chronic idiopathic urticaria (CIU)/chronic spontaneous urticaria (CSU) treated with omalizumab.

    Fast food consumption in pregnancy and subsequent asthma symptoms in young children

      Pediatric Allergy and Immunology Volume 26Issue 6pages 571–577, September 2015
    1. O. S. von Ehrenstein1,*
    2. H. Aralis2
    3. M. E. S. Flores3,4 and
    4. B. Ritz3

    Keywords:

    • asthma;
    • children;
    • epidemiology;
    • fast food;
    • maternal diet;
    • pregnancy

    Abstract

    Background

    Recent cross-sectional studies suggested children's current fast food consumption to be related to frequency of asthma and allergies. Maternal prenatal diet has been suspected to contribute to children's asthma and atopic disease risks.

    Fish and polyunsaturated fat intake and development of allergic and nonallergic rhinitis

    Background
    Rhinitis is one of the most common diseases in childhood. Fish, polyunsaturated fatty acid (PUFA), and vitamin D intakes have been hypothesized to affect the risk of allergic disease; however, it is unclear whether these are linked to the development of rhinitis.

    October 21, 2015

    Guidelines for the use and interpretation of diagnostic methods in adult food allergy

    Open Access
    Review


    Donatella Macchia1Giovanni Melioli2Valerio Pravettoni3Eleonora Nucera4Marta Piantanida3Marco Caminati5*,Corrado Campochiaro6Mona-Rita Yacoub6Domenico Schiavino4Roberto Paganelli7Mario Di Gioacchino8 and On behalf of the Food Allergy Study Group (ATI) of the Italian Society of Allergy, Asthma and Clinical Immunology (SIAAIC)

    Abstract

    Food allergy has an increasing prevalence in the general population and in Italy concerns 8 % of people with allergies. The spectrum of its clinical manifestations ranges from mild symptoms up to potentially fatal anaphylactic shock. A number of patients can be diagnosed easily by the use of first- and second-level procedures (history, skin tests and allergen specific IgE).