Helicobacter pylori in children with asthmatic conditions at school age, and their mothers

Early View (Online Version of Record published before inclusion in an issue)

1. W. J. den Hollander^1,2,*, 
2. A. M. M. Sonnenschein-van der Voort^2,3,4, 
3. I. L. Holster¹, 
4. J. C. de Jongste³, 
5. V. W. Jaddoe^2,5, 
6. A. Hofman⁴, 
7. G. I. Perez-Perez⁶, 
8. H. A. Moll⁵, 
9. M. J. Blaser⁶, 
10. L. Duijts^3,4,7 and
11. E. J. Kuipers^1,8
12. 1. 1. Abstract

       Background

       Helicobacter pylori prevalence in Western countries has been declining simultaneously with increases in childhood asthma and allergic diseases; prior studies have linked these phenomena.

       
       

       Aims

       To examine the association between H. pylori colonisation in children and risk of asthma and related conditions at school age. We secondly examined additional effects of maternal H. pylori status by pairing with children's status.

Prevalence of Peanut, Tree Nut, Sesame, and Seafood Allergy in Mexican Adults

VOLUME 67 - NUMBER 6 / November - December (Original Article)

Martín Bedolla-Barajas, Allergy and Clinical Immunology Service, Hospital Civil de Guadalajara Dr. Juan I. Menchaca, Guadalajara, Jal., Mexico

Tonatiuh Ramses Bedolla-Pulido, Allergy and Clinical Immunology Service, Hospital Civil de Guadalajara Dr. Juan I. Menchaca, Guadalajara, Jal., Mexico

Nicole Macriz-Romero, Universidad Autónoma de Guadalajara, Zapopan, Jal., Mexico

Jaime Morales-Romero, Instituto de Salud Pública, Universidad Veracruzana, Xalapa, Ver., Mexico

Martín Robles-Figueroa, Internal Medicine Service, Hospital Civil de Guadalajara Dr. Juan I. Menchaca, Guadalajara, Jal., Mexico

Abstract:

Objective: To identify the prevalence of perceived and probable allergic reactions to peanuts, tree nuts, sesame seed, or seafood and its association with the personal history of allergic disease. Methods: A cross-sectional study was performed in four cities of the metropolitan area of Guadalajara, located in western Mexico. Through sampling by gender and age, 1,126 subjects were included. Using a structured questionnaire, we investigated: (i) history of atopic disease, (ii) perception of allergic reaction after food intake, and (iii) probable allergic reaction to peanuts, tree nuts, sesame, or seafood. Prevalence and 95% confidence intervals were calculated. A multivariate analysis of factors associated to perceived and probable allergic reactions to food was performed by logistic regression.

Efficacy of MP-AzeFlu in children with seasonal allergic rhinitis: Importance of paediatric symptom assessment

Pediatric Allergy and Immunology

Volume 27, Issue 2, pages 126–133, March 2016

William Berger, 

Eli O. Meltzer, 

Niran Amar, 

Adam T. Fox, 

Jocelyne Just,

Antonella Muraro, 

Antonio Nieto, 

Erkka Valovirta, 

Magnus Wickman

 and

Jean Bousquet

Abstract

Background

This study aimed to assess the efficacy of MP-AzeFlu (a novel intranasal formulation of azelastine hydrochloride and fluticasone propionate in a single spray) in children with seasonal allergic rhinitis (SAR) and explore the importance of child symptom severity assessment in paediatric allergic rhinitis (AR) trials.

Helicobacter pylori infection is associated with a reduced risk of developing eosinophilic oesophagitis

Early View (Online Version of Record published before inclusion in an issue

1. U. von Arnim^1,*, 
2. T. Wex¹, 
3. A. Link¹, 
4. M. Messerschmidt¹, 
5. M. Venerito¹, 
6. S. Miehlke²and
7. P. Malfertheiner¹

DOI: 10.1111/apt.13560

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Summary

Background

Eosinophilic oesophagitis (EoE) represents a chronic immune-antigen-mediated allergic disease of the oesophagus of still unknown aetiology. Environmental exposure has been postulated to play a pathogenetic role. Helicobacter pylori (H. pylori) infection has been inversely associated with allergic diseases including atopic dermatitis, asthma and allergic rhinitis and H. pylori may play a protective role in these conditions. Little is known about the relationship between EoE and H. pylori.

Allergic Rhinitis and Chronic Daily Headaches: Is There a Link?

Open Access

Headache (R. B. Halker, Section Editor)

Current Neurology and Neuroscience Reports April 2016, 16:33

• Anna Gryglas 

Abstract

Allergic rhinitis and migraine remain on the list of the most common diseases affecting adults. Migraines and headaches due to allergic rhinitis are easily confused because the symptoms of both conditions often overlap. Both may occur with sinus headache, nasal congestion, and lacrimation and may worsen with weather changes and exposure to allergens. No precise clinical definition exists for what constitutes a sinus headache, which has always been a diagnostic dilemma.

Assessing Changes in Chronic Spontaneous/Idiopathic Urticaria: Comparisons of Patient-Reported Outcomes Using Latent Growth Modeling

Original Research

Advances in Therapy

February 2016, Volume 33, Issue 2, pp 214-224. First online: 30 January 2016

Open Access

Donald E. Stull 

, Doreen McBride 

, Katherine Houghton

, Andrew Y. Finlay

, Ari Gnanasakthy

,Maria-Magdalena Balp

Abstract

Introduction: Assessing the consequences of chronic spontaneous/idiopathic urticaria (CSU) requires the evaluation of health-related quality of life (HRQoL) associated with the severity of CSU signs and symptoms. It is important to understand how signs, symptoms, and HRQoL change over time in CSU. Evidence is lacking on how closely changes in signs and symptoms of CSU are related to changes in HRQoL.

Air pollution and chronic airway diseases: what should people know and do?

 

Vol 8, No 1 (January 2016) 

Authors: Xu-Qin Jiang, Xiao-Dong Mei, Di Feng

Abstract

The health effects of air pollution remain a public health concern worldwide. Exposure to air pollution has many substantial adverse effects on human health. Globally, seven million deaths were attributable to the joint effects of household and ambient air pollution. Subjects with chronic respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma are especially vulnerable to the detrimental effects of air pollutants. Air pollution can induce the acute exacerbation of COPD and onset of asthma, increase the respiratory morbidity and mortality.

Roflumilast combined with montelukast versus montelukast alone as add-on treatment in patients with moderate-to-severe asthma

Eric D. Bateman, MD

,

 Udo-Michael Goehring, MD

,

 Frank Richard, MD

,

 Henrik Watz, MD

Open Access

DOI: http://dx.doi.org/10.1016/j.jaci.2015.11.035

Article Info

• Abstract
• Full Text
• Images
• References

Background

Roflumilast, a selective phosphodiesterase 4 inhibitor, has been shown to provide modest improvements in lung function in patients with mild-to-moderate asthma, but its efficacy in patients with moderate-to-severe asthma has not been assessed. We hypothesized that this drug might provide benefit if combined with montelukast, a leukotriene receptor antagonist, in patients whose symptoms are uncontrolled by inhaled corticosteroids and long-acting β-agonists.

Management and Prevention of Anaphylaxis

F1000Res. 2015 Dec 22;4. pii: F1000 Faculty Rev-1492. doi: 10.12688/f1000research.7181.1. eCollection 2015.

Irani AM1, Akl EG1.

Author information

Abstract

Anaphylaxis prevalence has increased within the last few years. This may be due to a marked increase in allergic sensitization to foods especially in the pediatric population, as well as to an increase in outdoor recreational habits and the availability of new biologic medications.  Furthermore, guidelines for the diagnosis of anaphylaxis have been published, thus facilitating the recognition of this disorder.

The Treatment of Allergic Respiratory Disease During Pregnancy

Namazy JA1, Schatz M2

1Scripps Clinic, San Diego, California, USA 2Department of Allergy, Kaiser Permanente Medical Center, San Diego, California, USA

J Investig Allergol Clin Immunol 2016; Vol. 26(1): 1-7doi: 10.18176/jiaci.0001

Abstract Pregnancy may be complicated by new-onset or preexisting asthma and allergic rhinitis. This article reviews the recognition and management of asthma and allergic rhinitis during pregnancy, paying close attention to the general principles of allergy and use of asthma medication during pregnancy. Both allergic rhinitis and asthma can adversely affect both maternal quality of life and, in the case of maternal asthma, perinatal outcomes. Optimal management is thus important for both mother and baby. This article reviews the safety of asthma and allergy medications commonly used during pregnancy. Key words: Pregnancy. Asthma. Treatment. Inhaled corticosteroids. Bronchodilators. ß-agonists. Leukotriene modifiers. Oral corticosteroids.   Free Full-Text (PDF)   How to use PDF documents

Vaccination in patients with primary immune deficiency, secondary immune deficiency and autoimmunity with immune regulatory abnormalities

Immunotherapy Vol. 7, No. 12, Pages 1273-1292 , DOI 10.2217/IMT.15.74 (doi:10.2217/IMT.15.74) Review    This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 Unported License Martha M Eibl*,1 & Hermann M Wolf1 *Author for correspondence: martha.eibl@meduniwien.ac.at Vaccination has been an important healthcare measure in preventing infectious diseases. The response to vaccination is reduced in immunocompromised patients, primary immune deficiency (PID) and secondary immune deficiency (SID), but vaccination studies still demonstrated a protective effect resulting in reducing complications, hospitalization, treatment costs and even mortality.