October 2, 2017

Sublingual immunotherapy provides long-term relief in allergic rhinitis and reduces the risk of asthma: A retrospective, real-world database analysis

Open Access
Creative Commons

ORIGINAL ARTICLE

Authors

DOI: 10.1111/all.13213 View/save citation
Abstract

Background

Allergy immunotherapy (AIT) is the only treatment for allergic rhinitis (AR) and/or allergic asthma (AA) with long-term efficacy. However, there are few real-life data on the progression of AR and/or AA in patients receiving AIT.

Price, Alexandra MS*; Ramachandran, Sarika MD†; Smith, Gideon P. MD, PhD‡; Stevenson, Mary L. MD†; Pomeranz, Miriam K. MD†; Cohen, David E. MD, MPH†

Dermatitis: March/April 2015 - Volume 26 - Issue 2 - p 78–88

doi: 10.1097/DER.0000000000000087

Reviews

Oral allergy syndrome (OAS) or pollen-food allergy syndrome (PFS) is a hypersensitivity reaction to plant-based foods, manifesting most commonly with pruritus of the lips, tongue, and mouth. Unlike simple food allergy, OAS requires prior sensitization to a cross-reacting inhalant allergen rather than direct sensitization to a specific food protein. In this review, we summarize the clinical features and pathophysiology of OAS and provide an overview of known pollen-food associations.

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September 28, 2017

Molecular aspects of allergens in atopic dermatitis

Curr Opin Allergy Clin Immunol. 2017 August; 17(4): 269–277.

Published online 2017 July 28. doi: 10.1097/ACI.0000000000000378

PMCID: PMC5540349

Raffaela Campana,^a Sheron Dzoro,^a Irene Mittermann,^a Elena Fedenko,^b Olga Elisyutina,^b Musa Khaitov,^b Alexander Karaulov,^c and Rudolf Valenta^a

Author information ► Copyright and License information ►

Abstract

Purpose of review

Molecular allergology uses pure, mainly recombinant and structurally defined allergen molecules and allergen-derived epitopes to study mechanisms of IgE-associated allergy, to diagnose, and even predict the development of allergic manifestations and to treat and prevent IgE-associated allergies.

Fatal Anaphylaxis: Mortality Rate and Risk Factors

Paul J. Turner, MD, PhD

Elina Jerschow, MD

Thisanayagam Umasunthar, MD

Robert Lin, MD

Dianne E. Campbell, MD, PhD

Robert J. Boyle, MB, ChB, PhD

Correspondence information about the author MB, ChB, PhD Robert J. Boyle

Email the author MB, ChB, PhD Robert J. Boyle

Open Access

DOI: http://dx.doi.org/10.1016/j.jaip.2017.06.031

Article Info

Multicenter prevalence of anaphylaxis in clinic-based oral food challenges

Kwei Akuete, MD, MPH

Danielle Guffey, MS

Ryan B. Israelsen, MD

John M. Broyles, MS, CRNP

Lori Jo Higgins, LPN

Todd D. Green, MD

David R. Naimi, DO

Andrew J. MacGinnitie, MD, PhD

Girish Vitalpur, MD

Charles G. Minard, PhD

Carla M. Davis, MD

Correspondence information about the author MD Carla M. Davis

Email the author MD Carla M. Davis

Open Access

DOI: http://dx.doi.org/10.1016/j.anai.2017.07.028

Article Info

Passive blood anaphylaxis: subcutaneous immunoglobulins are a cause of ongoing passive anaphylactic reaction

Allergy, Asthma & Clinical Immunology

Allergy, Asthma & Clinical Immunology 2017 13:41

https://doi.org/10.1186/s13223-017-0213-x

Przemyslaw Zdziarski, Andrzej Gamian, Jacek Majda and Agnieszka Korzeniowska-Kowal

Abstract
Background
Allergic, especially anaphylactic, reactions during immunoglobulin replacement therapy are rare, but their pathophysiology and classification remain ambiguous. Recent findings show positive results of skin tests with commercially available immunoglobulins, but target antigens and responsible compounds of the tested immunoglobulins have not been strictly identified.

PloS One 2017, 12 (8): e0182295

Jae Hyun Lim, Jin Youp Kim, Doo Hee Han, Chul Hee Lee, Seung-No Hong, Jee Hye Wee, Sue K Park, Chae-Seo Rhe

INTRODUCTION: The aim of this study is to identify the effects of sublingual immunotherapy (SLIT) on immunologic parameters and bronchial-hyper-responsiveness in children with allergic rhinitis to house-dust mite (HDM), through long-term follow-up cohort.

Int Arch Allergy Immunol 2017;172:215-223

https://doi.org/10.1159/00046432

Griffiths R.L.M. · El-Shanawany T. · Jolles S.R.A. · Selwood C. · Heaps A.G. · Carne E.M. · Williams P.E.

Abstract

Background: Allergy is diagnosed from typical symptoms, and tests are performed to incriminate the suspected precipitant. Skin prick tests (SPTs) are commonly performed, inexpensive, and give immediate results. Laboratory tests (ImmunoCAP) for serum allergen-specific IgE antibodies are usually performed more selectively. The immuno-solid phase allergen chip (ISAC) enables testing for specific IgE against multiple allergen components in a multiplex assay.