Background
November 4, 2020
Anomalous asthma and chronic obstructive pulmonary disease Google Trends patterns during the COVID-19 pandemic
October 25, 2020
October 24, 2020
Validation of the DECA criteria for allergic conjunctivitis severity and control
- Research
- Open Access
Clinical and Translational Allergy 10, Article number: 43 (2020)
Abstract
Background
Allergic conjunctivitis (AC) is usually associated to allergic rhinitis (AR), but the severity and control of ocular symptoms should be assessed independently to improve diagnosis and treatment. The criteria from the Spanish consensus document on allergic conjunctivitis (DECA) aimed to be used as a patient-reported instrument for AC management. Here we validate these criteria for classifying AC severity and defining its control following COSMIN guidelines recommendations.
October 21, 2020
Comparative efficacy of glucocorticoid receptor agonists on Th2 cell function and attenuation by progesterone
- BMC Immunology Research article
- Open Access
Abstract
Background
Corticosteroids (CS)s suppress cytokine production and induce apoptosis of inflammatory cells. Prednisone and dexamethasone are oral CSs prescribed for treating asthma exacerbations. While prednisone is more commonly prescribed, dexamethasone is long acting and a more potent glucocorticoid receptor (GR) agonist. It can be administered as a one or two dose regime, unlike the five to seven days required for prednisone, a feature that increases compliance. We compared the relative ability of these two oral CSs to suppress type 2 inflammation. Since progesterone has affinity for the GR and women are more likely to relapse following an asthma exacerbation, we assessed its influence on CS action.
October 9, 2020
Current transition management of adolescents and young adults with allergy and asthma: a European survey
- Research
- Open Access
Clinical and Translational Allergy
Clinical and Translational Allergy 10, Article number: 40 (2020)
Background
Transition from parent-delivered to self-management is a vulnerable time for adolescents and young adults (AYA) with allergy and asthma. There is currently no European guideline available for healthcare professionals (HCPs) on transition of these patients and local/national protocols are also mostly lacking.
Methods
European HCPs working with AYA with allergy and asthma were invited to complete an online survey assessing challenges of working with these patients, current transition practices and access to specific healthcare resources.
October 4, 2020
World Allergy Organization Journal (Volume 13, Issue 10) - Published Articles Alert - October 4, 2020
Evaluation of oral immunotherapy efficacy and safety by maintenance dose dependency: A multicenter randomized study
Kiyotake Ogura, Noriyuki Yanagida, Sakura Sato, Takanori Imai, Komei Ito, Naoyuki Kando, Masanori Ikeda, Rumiko Shibata, Yoko Murakami, Takao Fujisawa, Mizuho Nagao, Norio Kawamoto, Naomi Kondo, Atsuo Urisu, Ikuya Tsuge, Yasuto Kondo, Kazuko Sugai, Osamu Uchida, Mitsuyoshi Urashima, Masami Taniguchi, Motohiro Ebisawa
Assessment of Google Trends terms reporting allergies and the grass pollen season in Ukraine
Igor Kaidashev, Halyna Morokhovets, Viktoriia Rodinkova, Lawrence DuBuske, Jean Bousquet
October 2, 2020
Management of the patient with allergic and immunological disorders in the pandemic COVID-19 era
- Review
- Open Access
- Clinical and Molecular Allergy
Clinical and Molecular Allergy 18, Article number: 18 (2020)
Abstract
The pandemic COVID-19 abruptly exploded, taking most health professionals around the world unprepared. Italy, the first European country to be hit violently, was forced to activate the lockdown in mid-February 2020. At the time of the spread, a high number of victims were quickly registered, especially in the regions of Northern Italy which have a high rate of highly-polluting production activities. The need to hospitalize the large number of patients with severe forms of COVID-19 led the National Health System to move a large number of specialists from their disciplines to the emergency hospital departments for the treatment of COVID-19. Furthermore, the lockdown itself has limited the possibility for general practitioners and pediatricians to be able to make outpatient visits and/or home care for patients with chronic diseases. Among them, the patient with atopic diseases, such as asthma, rhinitis and atopic dermatitis, is worthy of particular attention as she/he is immersed in a studded negative scenario with the onset of spring, a factor that should not be underestimated for those who suffer from pollen allergy. The Italian Society of Asthma Allergology and Clinical Immunology, to quickly deal with the lack of references and specialist medical procedures, has produced a series of indications for immunologic patient care that are reported in this paper, and can be used as guidelines by specialists of our discipline.
September 29, 2020
Psychosocial and productivity impact of caring for a child with peanut allergy
- Research
- Open Access
Allergy, Asthma & Clinical Immunology 16, Article number: 83 (2020)
Abstract
Background
Limited previous research has assessed the psychosocial burden and productivity impact of caring for a child with peanut allergy and factors associated with burden. The objective of this research was to explore caregiver burden in terms of psychosocial and productivity impact of caring for a child with peanut allergy, the influence of caregiver and child gender on caregiver burden, and factors predicting caregiver burden in peanut allergy.
September 17, 2020
Pneumothorax in COVID-19 disease- incidence and clinical characteristics
- Research
- Open Access
- Respiratory Research
Abstract
Background
Spontaneous pneumothorax is an uncommon complication of COVID-19 viral pneumonia. The exact incidence and risk factors are still unknown. Herein we review the incidence and outcomes of pneumothorax in over 3000 patients admitted to our institution for suspected COVID-19 pneumonia.
September 11, 2020
Azithromycin ameliorates sulfur dioxide-induced airway epithelial damage and inflammatory responses
- Research
- Open Access
Respiratory Research 21, Article number: 233 (2020)
Background
The airway epithelium (AE) forms the first line of defence against harmful particles and pathogens. Barrier failure of the airway epithelium contributes to exacerbations of a range of lung diseases that are commonly treated with Azithromycin (AZM).
The airway epithelium (AE) forms the first line of defence against harmful particles and pathogens. Barrier failure of the airway epithelium contributes to exacerbations of a range of lung diseases that are commonly treated with Azithromycin (AZM).
September 5, 2020
Effect of maternal sleep, physical activity and screen time during pregnancy on the risk of childhood respiratory allergies: a sex-specific study
- Respiratory Research
- Research
- Open Access
Respiratory Research 21, Article number: 230 (2020)
Abstract
Background
Early life exposure in the uterus had a long-term effect on children’s health. As the prevalence of allergies is increasing with a remarkable sex difference, very few studies have traced back to their early origins. We sought to investigate if maternal behavioral exposure, herein sleep, physical activity, and screen time during pregnancy is associated with childhood respiratory allergies. The sex difference would be examined.
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