October 5, 2018

Kimishige Ishizaka (1925–2018)

Dr. Kimishige Ishizaka (Fig. 1) passed peacefully away from heart failure at dawn of July 6, 2018 in Yamagata, Japan. Dr. Kimishige Ishizaka and Dr. Teruko Ishizaka (the Ishizakas; partners in marriage and in research) were best known for their discovery of immunoglobulin E (IgE) in 1966.1
Fig. 1 Opens large image

Fig. 1

Kimishige Ishizaka, December 3, 1925–July 6, 2018. A photo was taken at the reception celebrating the 50th Anniversary of IgE Discovery held at the 65th Annual Meeting of Japanese Society of Allergology, on June 19, 2016.

September 30, 2018

The prostaglandin D2 receptor 2 pathway in asthma: a key player in airway inflammation

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Abstract

Asthma is characterised by chronic airway inflammation, airway obstruction and hyper-responsiveness. The inflammatory cascade in asthma comprises a complex interplay of genetic factors, the airway epithelium, and dysregulation of the immune response.

Gut microbiota relationships to lung function and adult asthma phenotype: a pilot study

Lesa Begley1,  Siddharth Madapoosi1,  Kristopher Opron1,2,  Ogechukwu Ndum3,  Alan Baptist3,  Kelly Rysso1,  John R Erb-Downward1 and  Yvonne Jean Huang1
Abstract
Introduction Despite strong evidence that maturation patterns of the gut microbiome in early life influence the risk for childhood asthma, very little is known about gut microbiota patterns in adults with established asthma, and of greater interest relationships to phenotypic features that characterise asthma heterogeneity.

Seafood allergy: A comprehensive review of fish and shellfish allergens

Highlights

Immunological cross-reactivity between fish and shellfish allergens has not been demonstrated conclusively.

September 29, 2018

A comparative analysis of errors in inhaler technique among COPD versus asthma patients

Birsen Ocakli,Ipek Ozmen,Eylem Acartürk Tunçay,Sinem Gungor,1 Hilal Altinoz,1 Nalan Adiguzel,1Zafer Ali Sak,2 Gokay Gungor,Zuhal Karakurt,1 Peri Arbak3

1University of Health Sciences, Sureyyapasa Chest Diseases and Thoracic Surgery Training and Research Hospital, Istanbul, Turkey; 2Department of Chest Diseases, Harran University, Faculty of Medicine, Sanliurfa, Turkey; 3Department of Chest Diseases, Duzce University, Faculty of Medicine, Duzce, Turkey

Purpose: This study was designed to evaluate errors in inhaler technique in COPD vs asthma patients and to investigate the association of poor inhaler technique with patient demographics and clinical variables.

September 26, 2018

An observational cohort study of the use of five-grass-pollen extract sublingual immunotherapy during the 2015 pollen season in France

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Abstract

Background
Allergic rhinitis affects around one quarter of the Western European population. Prophylactic allergen immunotherapy may be useful to reduce the risk of acute symptomatic attacks (hayfever). A five-grass pollen extract sublingual immunotherapy (5GPE-SLIT) has been developed for the treatment of allergic rhinitis to grass pollen.

September 21, 2018

Duration of Allergen Immunotherapy for Long-Term Efficacy in Allergic Rhinoconjunctivitis

  • Martin Penagos 
  • Aarif O. Eifan 
  • Stephen R. Durham
  • Guy W. Scadding
  1. 1.
Open Access 
Specific Immunotherapy (L Cox, Section Editor)
Part of the following topical collections:
  1. Topical Collection on Specific Immunotherapy
Abstract

Rationale

Subcutaneous and sublingual immunotherapy are effective for allergic rhinitis. An important question is whether allergen immunotherapy provides a sustained clinical effect after treatment cessation. In view of potential side effects, cost and the necessary patient commitment, long-term benefit is an important consideration for the recommendation of immunotherapy over standard pharmacotherapy.

September 13, 2018

The following new articles have just been published in Allergy, Asthma & Clinical Immunology

Allergy, Asthma & Clinical Immunology

The following new articles have just been published in Allergy, Asthma & Clinical Immunology

REVIEW

Anaphylaxis

Allergy, Asthma & Clinical Immunology 2018, 14:54 | Published on: 12 September 2018
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