Non-celiac gluten/wheat sensitivity (NCGS)—a currently undefined disorder without validated diagnostic criteria and of unknown prevalence

Allergo Journal International

August 2018, Volume 27, Issue 5, pp 147–151| Cite as

Position statement of the task force on food allergy of the German Society of Allergology and Clinical Immunology (DGAKI)

• Authors
• Authors and affiliations

• Imke Reese
• Christiane Schäfer
• Jörg Kleine-Tebbe
• Birgit Ahrens
• Oliver Bachmann
• Barbara Ballmer-Weber
• Kirsten Beyer
• Stephan C. Bischoff
• Katharina Blümchen
• Sabine Dölle
• Paul Enck
• Axel Enninger
• Isidor Huttegger
• Sonja Lämmel
• Lars Lange

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Open Access

Abstract

Within the last decade, non-celiac gluten/wheat sensitivity (NCGS) has been increasingly discussed not only in the media but also among medical specialties. The existence and the possible triggers of NCGS are controversial.

Overview of Drug Allergy: From Immunogenetic Basis to Practice

Acta Med Port 2018 Oct;31(10):581-588 ▪ https://doi.org/10.20344/amp.10092

Eunice Dias de Castro, Fabrícia Carolino, Laura Ribeiro, Josefina R. Cernadas

Abstract

Drug therapy is often a balance between the beneficial and harmful effects of drugs. Drug allergic reactions are adverse reactions mediated by immunological mechanisms and usually not related to the pharmacological actions of the drug. They can be classified based either on the clinical presentation or the underlying immunological mechanism. Although uncommon, drug allergic reactions are unpredictable and can be very severe, even life threatening. The aim of this review was to provide clinicians from different medical specialties with a working tool to improve management of their patients with suspected drug allergy. It was conducted as a nonsystematic review, and attempts to describe the complexity of drug allergy.

A rare case report of polyangiitis overlap syndrome: granulomatosis with polyangiitis and eosinophilic granulomatosis with polyangiitis

BMC Pulmonary Medicine


                                      


• Case report
• Open Access
• Open Peer Review
• 
  

• Michele V. QuanEmail authorView ORCID ID profile,
• Stephen K. Frankel,
• Mehrnaz Maleki-Fischbach and
• Laren D. TanEmail author

BMC Pulmonary Medicine201818:181

https://doi.org/10.1186/s12890-018-0733-2

Open Peer Review reports

Abstract

Background

Granulomatosis with polyangiitis (GPA) is a systemic ANCA-associated vasculitis characterized by necrotizing granulomatous inflammation and a predilection for the upper and lower respiratory tract. Eosinophilic granulomatosis with polyangiitis (EGPA) is also a systemic ANCA-associated vasculitis, but EGPA is characterized by eosinophilic as well as granulomatous inflammation and is more commonly associated with asthma and eosinophilia.

MASK 2017: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma multimorbidity using real-world-evidence

• Clin Transl Allergy
• v.8; 2018
• PMC6201545

Clin Transl Allergy. 2018; 8: 45.

25. doi:  [10.1186/s13601-018-0227-6]

J. Bousquet,1,2,3 S. Arnavielhe,4 A. Bedbrook,1 M. Bewick,5 D. Laune,4 E. Mathieu-Dupas,4 R. Murray,6G. L. Onorato,1 J. L. Pépin,7,8 R. Picard,9 F. Portejoie,1 E. Costa,10 J. Fonseca,11,12 O. Lourenço,13M. Morais-Almeida,14 A. Todo-Bom,15 A. A. Cruz,16,17 J. da Silva,18 F. S. Serpa,19 M. Illario,20 E. Menditto,21L. Cecchi,22 R. Monti,23 L. Napoli,24 M. T. Ventura,25 G. De Feo,26 D. Larenas-Linnemann,27 M. Fuentes Perez,28Y. R. Huerta Villabolos,28 D. Rivero-Yeverino,29 E. Rodriguez-Zagal,30 F. Amat,31,32 I. Annesi-Maesano,33I. Bosse,34 P. Demoly,35 P. Devillier,36 J. F. Fontaine,37 J. Just,31,32 T. P. Kuna,38 B. Samolinski,39 A. Valiulis,40,41R. Emuzyte,42 V. Kvedariene,43 D. Ryan,44,45 A. Sheikh,46 P. Schmidt-Grendelmeier,47 L. Klimek,48,49O. Pfaar,48,49 K. C. Bergmann,50,51 R. Mösges,52,53 T. Zuberbier,50,51 R. E. Roller-Wirnsberger,54 P. Tomazic,55W. J. Fokkens,56 N. H. Chavannes,57 S. Reitsma,56 J. M. Anto,58,59,60,61 V. Cardona,62 T. Dedeu,63,64J. Mullol,65,66 T. Haahtela,67 J. Salimäki,68 S. Toppila-Salmi,67 E. Valovirta,69,70 B. Gemicioğlu,71A. Yorgancioglu,72,73 N. Papadopoulos,74,75 E. P. Prokopakis,76 S. Bosnic-Anticevich,77 R. O’Hehir,78,79J. C. Ivancevich,80 H. Neffen,81 E. Zernotti,82 I. Kull,83 E. Melen,84,85 M. Wickman,86 C. Bachert,87P. Hellings,3,88,89 S. Palkonen,90 C. Bindslev-Jensen,91 E. Eller,91 S. Waserman,92 M. Sova,93 G. De Vries,94M. van Eerd,94 I. Agache,95 T. Casale,96 M. Dykewickz,97 R. N. Naclerio,98 Y. Okamoto,99 D. V. Wallace,100 and MASK study group

Author information Article notes Copyright and License information Disclaimer

Abstract

mHealth, such as apps running on consumer smart devices is becoming increasingly popular and has the potential to profoundly affect healthcare and health outcomes. However, it may be disruptive and results achieved are not always reaching the goals.

Glutathione S-transferase (GST) of American Cockroach, Periplaneta americana: Classes, Isoforms, and Allergenicity

Article | OPEN | 

• Nitat Sookrung, 
• Onrapak Reamtong, 
• Rojana Poolphol, 
• Nitaya Indrawattana, 
• Watee Seesuay, 
• Nawannaporn Saelim, 
• Pongsakorn Tantilipikorn, 
• Chaweewan Bunnag, 
• Wanpen Chaicumpa & 
• Anchalee Tungtrongchitr 

Scientific Reportsvolume 8, Article number: 484 (2018) | Download Citation

Abstract

Insect glutathione S-transferases (GSTs) play important roles in insecticide/drug resistance and stress response. Medically, GSTs of house dust mites (Dermatophagoides pteronyssinus and Blomia tropicalis) and German cockroach (Blattella germanica) are human allergens. In this study, classes, isoforms and B-cell and allergenic epitopes of GST of American cockroach, Periplaneta americana, the predominant species in the tropics and subtropics were investigated for the first time. Enzymatically active native and recombinant P. americana-GSTs bound to IgE in sera of all P. americana allergic patients that were tested. By gel-based proteomics and multiple sequence alignments, the native GST comprises three isoforms of delta and sigma classes.

The diagnosis of hereditary angioedema with C1 inhibitor deficiency: a survey of Canadian physicians and laboratories

• Research
• Open Access

• Xavier Charest-MorinEmail authorView ORCID ID profile,
• Stephen Betschel,
• Rozita Borici-Mazi,
• Amin Kanani,
• Gina Lacuesta,
• Georges-Étienne Rivard,
• Eric Wagner,
• Susan Wasserman,
• Bill Yang and
• Christian Drouet

Allergy, Asthma & Clinical Immunology201814:83

https://doi.org/10.1186/s13223-018-0307-0

Abstract

Background

Hereditary angioedema due to C1 inhibitor deficiency (C1-INH-HAE) is an autosomal dominant disease resulting in random and unpredictable attacks of swelling. The swelling in C1-INH-HAE is a result of impaired regulation of bradykinin production.