- Review
- Open Access
Allergy, Asthma & Clinical Immunology
Abstract
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| Ocular signs of (a) chronic perennial allergic conjunctivitis (b–d) acute seasonal allergic conjunctivitis. |
January 22, 2020
A contemporary look at allergic conjunctivitis
Antibiotic hypersensitivity and adverse reactions: management and implications in clinical practice
- Research
- Open Access
- Allergy, Asthma & Clinical Immunology
Abstract
Background
Studies have shown the discrepancy between self-reported antibiotic allergies and true allergies. Inaccurate reporting of antibiotic hypersensitivities can limit treatment options and result in use of more expensive antibiotics and contribute to resistance.
January 20, 2020
Indoor mold odor in the workplace increases the risk of Asthma-COPD Overlap Syndrome: a population-based incident case–control study
- Research
- Open Access
Abstract
Background
Previous studies have suggested an increased risk of asthma related to indoor dampness problems, but their role in the etiology of Asthma-COPD Overlap Syndrome has not been studied. We utilized a population-based incident case–control study to assess potential effect of indoor dampness and molds at home and at work on development of ACOS.
January 18, 2020
Healthy people in healthy premises: the Finnish Indoor Air and Health Programme 2018–2028
- Research
- Open Access
Abstract
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| Main focus areas of Finnish Healthy Premises 2028 Programme. The Finnish Indoor Air and Health Programme implements and supports these measures (Enhancement of health and well-being) and closely collaborates with programme’s other actors |
Clean and fresh indoor air supports health and well-being. However, indoor air can contain pollutants that can cause a variety of symptoms and reduce well-being. Individual exposure agents can also increase the risk of certain diseases. Finns have taken major steps to improve the quality of indoor air for several decades. The primary focus of these activities has been the prevention and reduction of exposure to poor indoor air quality through guidance and regulation directing remediation of damaged buildings. Nevertheless, reported symptoms related to poor indoor air quality are common in Finland.
January 16, 2020
Association between atopic dermatitis and colorectal cancer risk
RESEARCH ARTICLE: OBSERVATIONAL STUDY
A nationwide cohort study
Abstract
The role of atopic dermatitis (AD) in the development of colorectal cancer (CRC) has been a matter of scientific debate with mixed results. We conducted a nationwide cohort study to assess the association between AD and risk of CRC. Drawing on Taiwan's National Health Insurance Research Database, 46,703 patients with AD (the AD cohort) and 186,812 sex, age, and index year-matched patients without AD (the non-AD cohort) were identified in the period between 2000 and 2008.
January 15, 2020
Clinical Management of Seafood Allergy
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Open Access
Article Info
Abstract
Seafood plays an important role in human nutrition and health. A good patient workup and sensitive diagnostic analysis of IgE antibody reactivity can distinguish between a true seafood allergy and other adverse reactions generated by toxins or parasites contaminating ingested seafood. The 2 most important seafood groupings include the fish and shellfish.
January 7, 2020
Use of antibiotics and asthma medication for acute lower respiratory tract infections in people with and without asthma: retrospective cohort study
- Research
- Open Access
Abstract
Background
Antibiotics are overused in patients with acute lower respiratory tract infections (ALRTIs), but less is known about their use in patients with asthma, or the use of asthma medication for ALRTI in patients without asthma. Our aim was to describe the frequency, variation and drivers in antibiotic and asthma medication prescribing for ALRTI in adults with and without asthma in primary care.
January 4, 2020
Future research trends in understanding the mechanisms underlying allergic diseases for improved patient care
Heimo Breiteneder Zuzana Diamant Thomas Eiwegger Wytske J. Fokkens Claudia Traidl‐Hoffmann Kari Nadeau Robyn E. O’Hehir Liam O’Mahony Oliver Pfaar Maria J. Torres De Yun Wang Luo Zhang Cezmi A. Akdis
REVIEW Open Access
Abstract
The specialties of allergy and clinical immunology have entered the era of precision medicine with the stratification of diseases into distinct disease subsets, specific diagnoses, and targeted treatment options, including biologicals and small molecules.
This article reviews recent developments in research and patient care and future trends in the discipline. The section on basic mechanisms of allergic diseases summarizes the current status and defines research needs in structural biology, type 2 inflammation, immune tolerance, neuroimmune mechanisms, role of the microbiome and diet, environmental factors, and respiratory viral infections. In the section on diagnostic challenges, clinical trials, precision medicine and immune monitoring of allergic diseases, asthma, allergic and nonallergic rhinitis, and new approaches to the diagnosis and treatment of drug hypersensitivity reactions are discussed in further detail.
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