Diagnostic Approach for Suspected Allergic Cutaneous Reaction to a Permanent Tattoo

Silvestre JF, González-Villanueva I

Servicio de Dermatología, Hospital General Universitario de Alicante, Alicante, Spain

J Investig Allergol Clin Immunol 2019; Vol 29(6) : 405-413doi: 10.18176/jiaci.0383

• Abstract

The last few decades have seen a notable increase in the number of people who have a tattoo. This practice is not free from complications. Most adverse effects appear early and are temporary, although they can occasionally develop later and be permanent and serious. Recent research has generated new knowledge on the composition of inks, their degradation over time, the immune activity that is stimulated, and the various clinical disorders that can arise. This information enables better approaches to diagnosis and management when complications arise. Diagnosing allergic reactions to permanent tattoo ink can be very challenging. This review aims to identify clinical and histological clues to help practitioners differentiate allergic reactions from other complications. We discuss the yield and appropriateness of skin tests and biopsies and propose an algorithm to guide the diagnostic process.

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Therapeutic Potential of Dupilumab in the Treatment of Chronic Rhinosinusitis with Nasal Polyps: Evidence to Date

Therapeutics and Clinical Risk Management » Volume 16

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Video abstract presented by Jean Kim.

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Jean Kim,^1,2 Robert Naclerio<sup>1

1</sup>Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA; ²Department of Medicine: Allergy and Clinical Immunology, Johns Hopkins University School of Medicine, Baltimore, MD, USA

Correspondence: Jean Kim
Johns Hopkins Bayview Medical Center, 4940 Eastern Ave, Suite A102B, Baltimore, MD 21224, USA
Tel +1 410-550-0460
Fax +1 410-550-2871
Email jeankim@jhmi.edu

Abstract: Chronic rhinosinusitis with nasal polyposis (CRSwNP) is one of the most severe forms of chronic rhinosinusitis. CRSwNP is characterized by nasal and facial congestion, loss of sense of smell, rhinorrhea, and post-nasal drip.

A contemporary look at allergic conjunctivitis

• Review
• Open Access
• 
  

Allergy, Asthma & Clinical Immunology

• Pascale Dupuis, 
• C. Lisa Prokopich, 
• Alexander Hynes & 
• Harold Kim 

Allergy, Asthma & Clinical Immunology volume 16, Article number: 5 (2020) 

Abstract

Ocular signs of (a) chronic perennial allergic conjunctivitis
(b–d) acute seasonal allergic conjunctivitis. 

Allergic eye disease is common, yet often overlooked in North America. In the U.S., up to 40% of the population is deemed to be affected and this number is growing. Symptoms and signs of ocular allergy can lead to decreased productivity and negatively impact quality of life (QoL). Various treatment options exist to achieve symptom control. For allergic conjunctivitis, ophthalmic agents include antihistamines, mast cell stabilizers, dual-activity agents, nonsteroidal anti-inflammatory drugs (NSAIDs), steroids and some off-label treatments. Immunotherapy is recommended as a therapeutic option.

Antibiotic hypersensitivity and adverse reactions: management and implications in clinical practice

• Research
• Open Access
• Allergy, Asthma & Clinical Immunology

• Anthony Jourdan, 
• Brijit Sangha, 
• Eric Kim, 
• Sohrab Nawaz, 
• Vikram Malik, 
• Radhika Vij & 
• Sudhir Sekhsaria 

Allergy, Asthma & Clinical Immunology volume 16, Article number: 6 (2020) 

Abstract

Background

Studies have shown the discrepancy between self-reported antibiotic allergies and true allergies. Inaccurate reporting of antibiotic hypersensitivities can limit treatment options and result in use of more expensive antibiotics and contribute to resistance.

Indoor mold odor in the workplace increases the risk of Asthma-COPD Overlap Syndrome: a population-based incident case–control study

• Research
• Open Access

Clinical and Translational Allergy

• Maritta S. Jaakkola, 
• Taina K. Lajunen & 
• Jouni J. K. Jaakkola 

Clinical and Translational Allergy volume 10, Article number: 3 (2020) 

• details

Abstract

Background

Previous studies have suggested an increased risk of asthma related to indoor dampness problems, but their role in the etiology of Asthma-COPD Overlap Syndrome has not been studied. We utilized a population-based incident case–control study to assess potential effect of indoor dampness and molds at home and at work on development of ACOS.

Healthy people in healthy premises: the Finnish Indoor Air and Health Programme 2018–2028

• Research
• Open Access
• 
  

• Jussi Lampi, 
• Anne Hyvärinen, 
• Marina Erhola, 
• Tari Haahtela, 
• Kyösti Haukipuro, 
• Ulla Haverinen-Shaughnessy, 
• Kaisa Jalkanen, 
• Kirsi Karvala, 
• Sanna Lappalainen, 
• Kari Reijula, 
• Hannele Rämö, 
• Markku Sainio, 
• Anniina Salmela, 
• Mika Salminen, 
• Tuula Vasankari & 
• Juha Pekkanen 

Clinical and Translational Allergy volume 10, Article number: 4 (2020) 

• details

Abstract

Main focus areas of Finnish Healthy Premises 2028 Programme.
The Finnish Indoor Air and Health Programme implements
and supports these measures (Enhancement of health and well-being)
 and closely collaborates with programme’s other actors

Clean and fresh indoor air supports health and well-being. However, indoor air can contain pollutants that can cause a variety of symptoms and reduce well-being. Individual exposure agents can also increase the risk of certain diseases. Finns have taken major steps to improve the quality of indoor air for several decades. The primary focus of these activities has been the prevention and reduction of exposure to poor indoor air quality through guidance and regulation directing remediation of damaged buildings. Nevertheless, reported symptoms related to poor indoor air quality are common in Finland.

Association between atopic dermatitis and colorectal cancer risk

RESEARCH ARTICLE: OBSERVATIONAL STUDY

A nationwide cohort study

Chou, Wan-Yun MS^a; Lai, Pin-Yu MS^b; Hu, Je-Ming MD^c,d,e; Hsu, Chih-Hsiung MS^c,f; Chen, Yong-Chen PhD^g,h; Tian, Yu-Feng MD^i,j; You, San-Lin PhD^g,h; Hsiao, Cheng-Wen MD^d; Chou, Yu-Ching PhD^a,b,∗; Sun, Chien-An ScD^h,k,∗

Section Editor(s): Kok., Victor C.

 Author Information

Medicine: January 2020 - Volume 99 - Issue 1 - p e18530

doi: 10.1097/MD.0000000000018530

Abstract

The role of atopic dermatitis (AD) in the development of colorectal cancer (CRC) has been a matter of scientific debate with mixed results. We conducted a nationwide cohort study to assess the association between AD and risk of CRC. Drawing on Taiwan's National Health Insurance Research Database, 46,703 patients with AD (the AD cohort) and 186,812 sex, age, and index year-matched patients without AD (the non-AD cohort) were identified in the period between 2000 and 2008.

Clinical Management of Seafood Allergy

January 2020 Volume 8, Issue 1, Pages 37–44

Carla M. Davis, MDa,∗,Correspondence information about the author MD Carla M. DavisEmail the author MD Carla M. Davis

, 

Ruchi S. Gupta, MD, MPHb

, 

Ozge N. Aktas, MDc

, 

Veronica Diaz, MDa

, 

Sandip D. Kamath, PhDd

, 

Andreas L. Lopata, PhDd

Open Access

DOI: https://doi.org/10.1016/j.jaip.2019.10.019

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Article Info

Abstract

Seafood plays an important role in human nutrition and health. A good patient workup and sensitive diagnostic analysis of IgE antibody reactivity can distinguish between a true seafood allergy and other adverse reactions generated by toxins or parasites contaminating ingested seafood. The 2 most important seafood groupings include the fish and shellfish.