June 22, 2020

Anaphylaxis to three humanized antibodies for severe asthma: a case study

  • Case report
  • Open Access

Allergy, Asthma & Clinical Immunology

Abstract

Background
Omalizumab, mepolizumab, benralizumab, and dupilumab are the currently available biologics used to treat asthma in Japan. Anaphylaxis following treatment with mepolizumab or benralizumab is considered rare.

June 20, 2020

Digital transformation of health and care to sustain Planetary Health: The MASK proof-of-concept for airway diseases—POLLAR symposium under the auspices of Finland’s Presidency of the EU, 2019 and MACVIA-France, Global Alliance against Chronic Respiratory Diseases (GARD, WH0) demonstration project, Reference Site Collaborative Network of the European Innovation Partnership on Active and Healthy Ageing

Clinical and Translational Allergy

  • […]
  • Abstract
    In December 2019, a conference entitled “Europe That Protects: Safeguarding Our Planet, Safeguarding Our Health” was held in Helsinki. It was co-organized by the Finnish Institute for Health and Welfare, the Finnish Environment Institute and the European Commission, under the auspices of Finland’s Presidency of the EU. As a side event, a symposium organized as the final POLLAR (Impact of air POLLution on Asthma and Rhinitis) meeting explored the digital transformation of health and care to sustain planetary health in airway diseases.


    The Finnish Allergy Programme collaborates with MASK (Mobile Airways Sentinel NetworK) and can be considered as a proof-of-concept to impact Planetary Health. The Good Practice of DG Santé (The Directorate-General for Health and Food Safety) on digitally-enabled, patient-centred care pathways is in line with the objectives of the Finnish Allergy Programme.

    June 18, 2020

    World Allergy Week 2020 - 28 June - 4 July 2020

    World Allergy Week 2020


    The World Allergy Organization is proud to announce that World Allergy Week 2020 will occur 28 June - 4 July 2020 and will focus on the theme of "Allergy care does not stop with COVID-19."
    Each year, the World Allergy Organization (WAO) addresses a different topic that has a need for greater awareness. To accomplish this, WAO provides physicians and the general public with a webinar, infographic, and additional information to educate and spread awareness on the topic. Additional details on these items will be coming soon.


    Join us for a World Allergy Week webinar on 2 July 2020 at 8:00 am EDT. Time zone converter
    COVID-19 and Allergic Diseases
    Introduction
    Motohiro Ebisawa, Japan
    International perspective on the COVID-19 pandemic and allergic diseases
    Gary Wing Kin Wong, Hong Kong
    Psychological effects of the COVID-19 pandemic on allergic patients
    Sandra González Díaz, Mexico
    Effect of COVID-19 on the treatment of allergic patients
    Bryan Martin, USA
    How does the COVID-19 pandemic affect our asthma patients?
    Mário Morais-Almeida, Portugal
    Pediatric issues related to allergy and COVID-19
    Elham Hossny, Egypt
    Registration information coming soon.

    June 17, 2020

    Hoy Jueves 18/06/2020 3 webinars casi simultáneos

    Hoy 3 webinars casi simultáneos. Elija en cuál participar y cuáles reservar para verlos tranquilos el fin de semana (seguramente serán grabados y distribuidos los links por los organizadores:


    https://event.webinarjam.com/register/663/yy1k4cq58



    https://makmedia1.clickmeeting.com/eurofarma-rinitis


    Que los disfruten!

    June 8, 2020

    Viral infections and wheezing–asthma inception in childhood: is there a role for immunomodulation by oral bacterial lysates?

    • Review
    • Open Acces

    Abstract
    Severe and recurrent infections of the respiratory tract in early childhood constitute major risk factors for the development of bronchial hyper-responsiveness and obstructive respiratory diseases in later life. In the first years of life, the vast majority of respiratory tract infections (RTI) leading to wheezing and asthma are of a viral origin and severity and recurrence are the consequence of a greater exposure to infectious agents in a period when the immune system is still relatively immature.

    June 3, 2020

    Bruton’s tyrosine kinase inhibition effectively protects against human IgE-mediated anaphylaxis

     

    Abstract
    No known therapies can prevent anaphylaxis. Bruton’s tyrosine kinase (BTK) is an enzyme thought to be essential for high-affinity IgE receptor (FcεRI) signaling in human cells. We tested the hypothesis that FDA-approved BTK inhibitors (BTKi’s) would prevent IgE-mediated responses including anaphylaxis. We showed that irreversible BTKi’s broadly prevented IgE-mediated degranulation and cytokine production in primary human mast cells and blocked allergen-induced contraction of isolated human bronchi.