Cutaneous manifestations of COVID-19 and COVID-19 vaccination

Nakashima C, Kato M, Otsuka A. J Dermatol. 2023 Jan 13. doi: 10.1111/1346-8138.16651. Epub ahead of print.

Abstract

In December 2019, a new infectious pathogen named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified in Wuhan, China. Transmitted through respiratory droplets, SARS-CoV-2 is the causative pathogen of coronavirus disease 2019 (COVID-19). Although this new COVID-19 infection is known to cause primarily interstitial pneumonia and respiratory failure, it is often associated with cutaneous manifestations as well.

Analysis of factors influencing the determination of indications for allergen-specific immunotherapy

REVIEW ARTICLE

Bo Ding^a, Shiwen Gao^b, Jun Huang^c, Songdi Gong^d, Jiahui Lin^d, Guoliang Ding^e, Qiuzhi Shen^a, Wentao Wang^f, Mei Yang^g, Hui Wang^h, Chunmei Shenⁱ, Yanming Lu^a*

Allergol Immunopathol (Madr). 2023 Jan 1;51(1):168-176. doi: 10.15586/aei.v51i1.756.

Abstract

Objective: To develop a questionnaire and a scoring system for evaluating physicians’ knowledge of allergen immunotherapy (AIT).

Methods: Questionnaire was designed using the Questionnaire Star tool. A total of 1024 physicians were assessed, and based on the score divided into accurate judgment and inaccurate judgment groups. Statistical analysis was done, and counting data were expressed as frequencies and percentage values. Chi-square test and multi-factor logistic analysis were used to determine influencing factors on the indications for AIT.

Changes in type 2 innate lymphoid cells and serum cytokines in sublingual immunotherapy in pediatric patients with allergic rhinitis

Xiaoqiang Wang, 

Yang Shen, 

Suling Hong, 

Houyong Kang & 

Xia Ke 

BMC Pediatrics volume 23, Article number: 13 (2023) 

Abstract

Background

Type 2 innate lymphoid cells (ILC2) are upregulated in childhood allergic rhinitis (AR) and are associated with AR severity. This study aimed to investigate changes in the ILC2 milieu in pediatric patients with AR after sublingual immunotherapy (SLIT).

Clinical Associations of Mucus Plugging in Moderate to Severe Asthma

Open Access

J Allergy Clin Immunol Pract. 2022 Sep 21:S2213-2198(22)00943-6. doi: 10.1016/j.jaip.2022.09.008.

Background

Mucus plugging is recognized as a contributory factor to airway obstruction and symptoms in persistent asthma.

Objective

We aimed to determine phenotypic associations of mucus plugging in patients with moderate to severe asthma in a real-life clinic setting.

Immunomodulatory effects of probiotic supplementation in patients with asthma: a randomized, double-blind, placebo-controlled trial

Research - Open Access

Sina Sadrifar, Tannaz Abbasi-Dokht, Sarvenaz Forouzandeh, Farhad Malek, Bahman Yousefi, Amir Salek Farrokhi, Jafar Karami & Rasoul Baharlou 

Allergy, Asthma & Clinical Immunology volume 19, Article number: 1 (2023) 

Abstract

Background

Asthma is considered to be a chronic inflammatory disorder of the airways. Probiotics are living microorganisms that are found in the human gut and have protective effects against a wide range of diseases such as allergies. The aim of this study was to investigate the improvement of clinical asthma symptoms and changes in the expression pattern of selective microRNAs in patients with asthma and the changes in IL-4 and IFN-γ plasma levels after receiving probiotics.

Physician education on World Asthma Day aids in disease management during the COVID-19

• Short Report
• Open Access
• 
  

• Angyang Cao, 
• Yanling Zhou, 
• Wenjun Luo, 
• Dan Lv, 
• Zhonghao Shao, 
• Binbin Zhu & 
• Jianhua Wang 

Allergy, Asthma & Clinical Immunology volume 18, Article number: 113 (2022) 

• details

Abstract

Anxiety and depression can negatively affect the management of asthma. The study aimed to assess the psychosocial effects of asthma patients during COVID-19 and analyze potential risk factors and interventions.

In June 2022, the “Questionnaire Star” electronic questionnaire system was used to collect data. A total of 98 asthma patients from the affiliated hospital of the medical school of Ningbo University were invited to complete the questionnaires. According to our study, the prevalence of symptoms of anxiety and depression in the asthma patients in the institution was 91.8 and 77.6%, respectively.

Nutritional Management of Children with Food Allergies

K. Wright BSc Nutrition, Dietetics, MSc Allergy, 

M. Feeney MSc Nutrition, PGDip Dietetics, 

N. Yerlett BSc Nutrition, Dietetics, PGDip & 

Rosan Meyer BSc Dietetics, M. Nutrition, PhD 

Current Treatment Options in Allergy volume 9, pages375–393 (2022)

• details

Abstract

Purpose of the Review

The purpose of the review is to review the evidence for the nutritional management of paediatric food allergy and provide a practical approach for healthcare professionals working in this area.

Immunoglobulin replacement therapy in patients with immunodeficiencies: impact of infusion method on patient-reported outcomes

• Research
• Open Access

Rajiv Mallick, 

Geneviève Solomon, 

Paul Bassett, 

Xiang Zhang, 

Palak Patel & 

Oleksandra Lepeshkina 

Allergy, Asthma & Clinical Immunology volume 18, Article number: 110 (2022) 

• details

Abstract

Background

Understanding the impact of different immunoglobulin (Ig) infusion methods (intravenous [IVIg] and subcutaneous [SCIg]) upon treatment experience can potentially facilitate optimization of patient outcomes. Here, the perspective of patients with primary and secondary immunodeficiency diseases (PID and SID, respectively) receiving IVIg and SCIg was evaluated, in terms of treatment satisfaction, accounting for treatment history, using Association des Patients Immunodéficients du Québec (APIQ) survey data.