October 30, 2014
Expert roundtable on Sublingual Immunotherapy
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Expert Roundtable on
Sublingual Immunotherapy
FACULTY:
Linda Cox, MD, FAAAAI • Thomas Casale, MD, FAAAAI • Peter Creticos, MD, FAAAAI • Stephen Durham, MA, MD, FRCP |
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| RELEASE DATE: September 15, 2014 • EXPIRATION DATE: September 15, 2016 |
Diagnosis and management of food allergies: new and emerging options: a systematic review
Authors Andrew W O'Keefe,1,2 Sarah De Schryver,1 Jennifer Mill,3 Christopher Mill,3 Alizee Dery,1 Moshe Ben-Shoshan1
Published Date October 2014 Volume 2014:7 Pages 141—164
Received 15 July 2014, Accepted 19 August 2014, Published 24 October 2014
Approved for publication by Dr Linda Cox
SLIT: indications, follow-up, and management
I Dávila1, A Navarro2, J Domínguez-Ortega3, A Alonso4, D Antolín-Amérigo5, MC Diéguez6, E González-Mancebo7, C Martín8, C Martínez9, B Núñez10, N Prior11, M Reche12, A Rosado13, J Ruiz-Hornillos14, A Sansosti15, M Torrecillas16, MJ Jerez17; QUASAR Group (QUality in the Administration of SLIT in Allergic Rhinitis)
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October 28, 2014
Histamine H4 receptor: A Novel Drug Target For Immunoregulation and Inflammation. Open Access Book
Aims and Scope
H4R is the newest member of the histamine receptor family, which was discovered about twelve years ago. It is considered a very promising drug target. The effort to improve the pharmacokinetic properties of the currently available H4R ligands is reflected in a steadily growing number of scientific publications and patent applications. Preclinical data strongly confirms the need for novel potent H4R ligands to explore their therapeutic value in allergy, inflammation, autoimmune disorders, and possibly, cancer.
Readers will be provided with extensive knowledge on histamine metabolism, as well as cellular histamine transport, storage and release, effects of histamine and histamine receptor ligands, with particular attention to the H4R, on inflammatory cells including mast cells, basophils, eosinophils, neutrophils, macrophages, dendritic cells, and T cells. The present knowledge on the regulatory role of histamine and the therapeutic exploitation of histamine receptor ligands in atopic diseases, with emphasis on human and animal models of asthma, allergic dermatitis and pruritus are discussed.
Readers will be provided with extensive knowledge on histamine metabolism, as well as cellular histamine transport, storage and release, effects of histamine and histamine receptor ligands, with particular attention to the H4R, on inflammatory cells including mast cells, basophils, eosinophils, neutrophils, macrophages, dendritic cells, and T cells. The present knowledge on the regulatory role of histamine and the therapeutic exploitation of histamine receptor ligands in atopic diseases, with emphasis on human and animal models of asthma, allergic dermatitis and pruritus are discussed.
October 27, 2014
Drug Allergy: Diagnosis and Management of Drug Allergy in Adults, Children and Young People
NICE Clinical Guidelines, No. 183
National Clinical Guideline Centre (UK).
London: National Institute for Health and Care Excellence (UK); 2014 Sep.
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