Histamine H1 antagonist levocetirizine as a potential cause of lung injury

Respirology Case Reports. Early View (Online Version of Record published before inclusion in an issue)

Satoshi Endo, Yasushi Yamamoto, Yoshinori Minami, Shunsuke Okumura, Takaaki Sasaki and Yoshinobu Ohsak

Abstract

Histamine H1 antagonists rarely cause drug-induced lung injury (DLI). A woman in her 60s, who had been taking antihistaminic levocetirizine for 2 months, presented with progressive cough and shortness of breath. A chest radiograph showed patchy infiltrations on both lower lung fields.

Dietary ​cholesterol directly induces acute inflammasome-dependent intestinal inflammation

NATURE COMMUNICATIONS | ARTICLE OPEN

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• Fränze Progatzky,
• Navjyot J. Sangha,
• Nagisa Yoshida,
• Marie McBrien,
• Jackie Cheung,
• Alice Shia,
• James Scott,
• Julian R. Marchesi,
• Jonathan R. Lamb,
• Laurence Bugeon
• & Margaret J. Dallman

• Affiliations
• Contributions
• Corresponding author

Nature Communications

 

5,

 

Article number:

 

5864

 

doi:10.1038/ncomms6864

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Abstract

• Abstract• 
• Introduction• 
• Results• 
• Discussion• 
• Methods• 
• Additional information• 
• References•
• Acknowledgements• 
• Author information• 
• Supplementary information

Prolonged ingestion of a ​cholesterol- or saturated fatty acid-enriched diet induces chronic, often systemic, auto-inflammatory responses resulting in significant health problems worldwide. In vivo information regarding the local and direct inflammatory effect of these dietary components in the intestine and, in particular, on the intestinal epithelium is lacking.

Analysis of various risk factors predisposing subjects to allergic rhinitis

Vol. 33, No. 2, June 2015 (Ahead of print)

Soo-Youn An, Hyo Geun Choi, Si Whan Kim, Bumjung Park, Joong Seob Lee, Jeong Hun Jang, Myung-Whun Sung

Abstract

Background: In Korea, the prevalence of allergic rhinitis (AR) is increasing, as in other industrialized countries. However, no large population-based study defining risk factors for AR has yet been conducted.

Objective: The purpose of this study was to evaluate the prevalence and risk factors of AR in large population-based study.

Methods: A cross-sectional study was performed using data from the Korea National Health and Nutrition Examination Survey. We evaluated data from 31,217 subjects who were interviewed between 2008 and 2011.

Effects of inactivated influenza vaccine on respiratory illnesses and asthma-related events in children with mild persistent asthma in Asia

Vol. 33, No. 1, March 2015 > Jaiwong
Charoen Jaiwong, Jarungchit Ngamphaiboon

Abstract

Background:    Acute asthmatic exacerbation and readmission may be associated with severe influenza infection and asthmatic children are a priority group for influenza vaccination. To date, our study is the first to evaluate the outcome of the influenza vaccine in asthmatic Asian children.

Swimming pool attendance is related to asthma among atopic school children: a population-based study

Research

Martin Andersson^12*, Linnea Hedman¹², Gunnar Nordberg¹, Bertil Forsberg¹, Kåre Eriksson¹ and Eva Rönmark¹²

Environmental Health 2015, 14:37  doi:10.1186/s12940-015-0023-x

Abstract

Background

By-products of water disinfectants have been suggested to cause asthma, especially in atopic children. However, studies on indoor swimming pool attendance and asthma in children have presented conflicting results. The present study examined the relationship between indoor swimming pool attendance and asthma among sensitized and non-sensitized children aged 11-12 years.

Uptake and impact of a clinical diagnostic decision support tool at an academic medical center

John S. Barbieri1 / Benjamin French1 / Craig A. Umscheid1

1Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA

Corresponding author: Craig A. Umscheid, MD, MS, Perelman School of Medicine at the University of Pennsylvania, 3535 Market Street, Mezzanine, Suite 50, Philadelphia, PA 19104, Phone: +215-349-8098, Fax: +215-349-5829, E-mail:(email)

©2015, Craig A. Umscheid et al., published by De Gruyter. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. (CC BY-NC-ND 3.0)

Citation Information: Diagnosis. ISSN (Online) 2194-802X, ISSN (Print) 2194-8011, DOI: 10.1515/dx-2014-0058, March 2015

Abstract

Background: Use of differential diagnosis (DDX) generators may reduce the incidence of misdiagnosis-related harm, but there is a paucity of research examining the use and impact of such systems in real-world settings.

Allergic contact dermatitis caused by dorzolamide eyedrops

Clinical Ophthalmology

Authors Lee SJ, Kim M

Published Date April 2015 Volume 2015:9 Pages 575—577

DOI http://dx.doi.org/10.2147/OPTH.S74555

Seung-Jun Lee, Moosang Kim

Department of Ophthalmology, School of Medicine, Kangwon National University, Chuncheon, Korea

Abstract: The side effects of topical dorzolamide hydrochloride, such as conjunctivitis, eyelid edema, and eye lid irritation, are well known.

Evaluating the impact of an integrated computer-based decision support with person-centered analytics for the management of asthma in primary care: a randomized controlled trial

Robyn Tamblyn , Pierre Ernst , Nancy Winslade , Allen Huang , Roland Grad , Robert W. Platt , Sara Ahmed , Teresa Moraga ,Tewodros EgualeDOI: http://dx.doi.org/10.1093/jamia/ocu009

Abstract

Background Computer-based decision support has been effective in providing alerts for preventive care. Our objective was to determine whether a personalized asthma management computer-based decision support increases the quality of asthma management and reduces the rate of out-of-control episodes.