July 10, 2015

Racial differences in eosinophilic gastrointestinal disorders among Caucasian and Asian

Volume 64, Issue 3, July 2015, Pages 253–259
Open Access
Original article


Abstract

Background

Although there is an increasing number of eosinophilic gastrointestinal disorders (EGID) cases including eosinophilic esophagitis (EoE) and eosinophilic gastroenteritis (EGE), being reported globally, no systematic reviews have been conducted to elucidate the racial differences in these disorders. We aimed to show the racial differences, especially among Caucasians and Asians, in the risk of EoE and EGE.

Allergic and non-allergic rhinitis: relationship with nasal polyposis, asthma and family history

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Acta Otorhinolaryngol Ital. 2014 Feb; 34(1): 36–41.
PMCID: PMC3970223
Language: English | Italian

Allergic and non-allergic rhinitis: relationship with nasal polyposis, asthma and family history

SUMMARY
Rhinitis and rhinosinusitis (with/without polyposis), either allergic or non-allergic, represent a major medical problem. Their associated comorbidities and relationship with family history have so far been poorly investigated. We assessed these aspects in a large population of patients suffering from rhinosinusal diseases.

July 9, 2015

Efficacy and safety of beclomethasone dipropionate nasal aerosol in children with perennial allergic rhinitis

Abstract

Background

Beclomethasone dipropionate (BDP) nasal aerosol (non-aqueous) is approved for management of seasonal and perennial allergic rhinitis (PAR) in adolescents and adults.

Objective

To evaluate the efficacy and safety of BDP nasal aerosol at 80 μg/day in children with PAR.

July 8, 2015

Altered microRNA Expression Profiles of Extracellular Vesicles in Nasal Mucus From Patients With Allergic Rhinitis


Original Article  Open Access


      

Allergy Asthma Immunol Res. 2015 Sep;7(5):449-457. English.
Published online Apr 14, 2015.  http://dx.doi.org/10.4168/aair.2015.7.5.449 
Copyright © 2015 The Korean Academy of Asthma, Allergy and Clinical Immunology • The Korean Academy of Pediatric Allergy and Respiratory Disease
Geping Wu,1 Guanghai Yang,6 Ruxin Zhang,2 Guangyin Xu,3 Ling Zhang,4 Wu Wen,5 Jianbing Lu,1 Jianyong Liu,1 and Yan Yu1

Abstract

Purpose
Allergic rhinitis (AR) is an inflammatory disorder of the upper airway. Exosomes or extracellular vesicles are nanosized vesicles of endosomal origin released from inflammatory and epithelial cells that have been implicated in allergic diseases. In this study, we characterized the microRNA (miRNA) content of exosomes in AR.

A survey of clinical features of allergic rhinitis in adults

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Med Sci Monit. 2014; 20: 2151–2156.
Published online 2014 Nov 4. doi:  10.12659/MSM.891206
PMCID: PMC4228947
Franco Frati,1,A Ilaria Dell’Albani,1,A Giovanni Passalacqua,2,B Sergio Bonini,3,B Oliviero Rossi,4,B Gianenrico Senna,5,B and Cristoforo Incorvaia6,E,F, on behalf of The Adult SURF Study Group
Abstract
Background
Allergic rhinitis (AR) has high prevalence and substantial socio-economic burden.
Material/Methods
The study included 35 Italian Centers recruiting an overall number of 3383 adult patients with rhinitis (48% males, 52% females, mean age 29.1, range 18–45 years).

July 6, 2015

Approaches to the diagnosis and management of chronic urticaria in children

REVIEW ARTICLE
Korean J Pediatr 2015 May;58(5) :159-164.
Published online 2015 May 15.       
Sun Hee Choi1Hey Sung Baek2
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ABSTRACT
Most guidelines for chronic urticaria (CU) in infants and children are based on limited pediatric evidence. Current evidence used to guide treatment in children is extrapolated from data focusing on older age groups. CU in children is a different and complex condition than that in adults. Furthermore, there is little published information regarding urticaria in Korean children. The aim of the present article is to review recent research on chronic childhood urticaria and improve the current understanding of its pathogenesis and management.

Asthma trajectories in early childhood: identifying modifiable factors

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PLoS One. 2014; 9(11): e111922.
Published online 2014 Nov 7. doi:  10.1371/journal.pone.0111922
PMCID: PMC4224405
Abstract
Background
There are conflicting views as to whether childhood wheezing represents several discreet entities or a single but variable disease. Classification has centered on phenotypes often derived using subjective criteria, small samples, and/or with little data for young children. This is particularly problematic as asthmatic features appear to be entrenched by age 6/7. In this paper we aim to: identify longitudinal trajectories of wheeze and other atopic symptoms in early childhood; characterize the resulting trajectories by the socio-economic background of children; and identify potentially modifiable processes in infancy correlated with these trajectories.

A systematic review of associations between environmental exposures and development of asthma in children aged up to 9 years

  • Paediatrics

A systematic review of associations between environmental exposures and development of asthma in children aged up to 9 years

Abstract

Objectives Childhood asthma is a complex condition where many environmental factors are implicated in causation. The aim of this study was to complete a systematic review of the literature describing associations between environmental exposures and the development of asthma in young children.