|
A blog that publishes updates and open access scientific papers about allergy, asthma and immunology. Editor: Juan Carlos Ivancevich, MD. Specialist in Allergy & Immunology
July 26, 2015
Addition of Montelukast to Low-Dose Inhaled Corticosteroid Leads to Fewer Exacerbations in Older Patients
Engineered metal based nanoparticles and innate immunity
Abstract
Almost all people in developed countries are exposed to metal nanoparticles (MeNPs) that are used in a large number of applications including medical (for diagnostic and therapeutic purposes). Once inside the body, absorbed by inhalation, contact, ingestion and injection, MeNPs can translocate to tissues and, as any foreign substance, are likely to encounter the innate immunity system that represent a non-specific first line of defense against potential threats to the host. In this review, we will discuss the possible effects of MeNPs on various components of the innate immunity (both specific cells and barriers).
Food dependant exercise induced anaphylaxis a retrospective study from 2 allergy clinics in Colombo, Sri Lanka
Case report
Nilhan Rajiva de Silva1*, Wasala Mudiyanselage Dhanushka Kumari Dasanayake1, Chandima Karunatilleke1 andGathsauri Neelika Malavige2
Abstract
The aetiology of anaphylaxis ranges from food, insect venom, drugs and various chemicals. Some individuals do not develop anaphylaxis with the offending agent unless ingestion is related temporally to physical exertion, namely food dependent exercise induced anaphylaxis (FDEIA).
July 25, 2015
Randomised, double-blind, placebo-controlled crossover study to investigate different dosing regimens of olodaterol delivered via Respimat® in patients with moderate to severe persistent asthma
Research
Kai-Michael Beeh1*, Craig LaForce2, Martina Gahlemann3, Arne Wenz4, Robert Toorawa5 and Matjaž Fležar6
Abstract
Background
A Phase II, multicentre, randomised, double-blind, placebo-controlled, crossover trial comparing the 24-h forced expiratory volume in 1 s (FEV 1 ) time profile after 3 weeks’ treatment with once-daily (QD) or twice-daily (BID) olodaterol (at the same total daily dose) versus placebo delivered via Respimat® in patients with moderate to severe asthma.
July 23, 2015
In Vitro Evaluation of Allergen Potencies of Commercial House Dust Mite Sublingual Immunotherapy Reagents
| ||||||||||||
|
Activation of the Intrinsic Coagulation Pathway in Patients With Chronic Urticaria
|
Allergy Asthma Immunol Res. 2015 Sep;7(5):476-482. English. Published online May 22, 2015. http://dx.doi.org/10.4168/aair.2015.7.5.476 |
Jung-Ah Kim,1, Sujeoung Kim,2,3, Ji-Eun Kim,1,4 Ja-Yoon Gu,1,4 Hyun Ju Yoo,1,4 Hye-Ryun Kang,2 and Hyun Kyung Kim1,4 | |
Abstract
| |
Purpose
Although coagulation activation has been reported in chronic urticaria, data pertaining to detailed changes in coagulation factors and global coagulation status are lacking. The current study evaluated global coagulation status in patients with chronic urticaria using thrombin generation assay (TGA) and the levels of individual coagulation factors.
|
Retrospective case note review of chronic spontaneous urticaria outcomes and adverse effects in patients treated with omalizumab or ciclosporin in UK secondary care
Research
Sinisa Savic1, Alexander Marsland2, David McKay3, Michael R Ardern-Jones4, Tabi Leslie56, Olivier Somenzi7, Laura Baldock8 and Clive Grattan69*
Abstract
Background
Omalizumab is approved in the UK as add-on treatment for chronic spontaneous urticaria (CSU) in patients with inadequate response to H 1 -antihistamines. Ciclosporin is an established but unlicensed 3rd line option for CSU. Two parallel retrospective observational studies were conducted to describe outcomes of treatment and adverse events with omalizumab or ciclosporin for CSU treatment.
Hypersensitivity to Nonsteroidal Anti-inflammatory Drugs in Children and Adolescents: Cross-Intolerance Reactions
|
Subscribe to:
Posts (Atom)