A blog that publishes updates and open access scientific papers about allergy, asthma and immunology. Editor: Juan Carlos Ivancevich, MD. Specialist in Allergy & Immunology
September 21, 2015
High Prevalence of Neutrophil Cytoplasmic Autoantibodies in Infants with Food Protein-Induced Proctitis/Proctocolitis: Autoimmunity Involvement?
Journal of Immunology Research
Volume 2015 (2015), Article ID 902863, 8 pages
http://dx.doi.org/10.1155/2015/902863
Research Article
Alena Sekerkova,1 Martin Fuchs,2 Eva Cecrdlova,1 Veronika Svachova,1 Ivana Kralova Lesna,3 Ilja Striz,1 and Helena Tlaskalova-Hogenova4
1Department of Clinical and Transplant Immunology, Institute for Clinical and Experimental Medicine, 140 21 Prague, Czech Republic
2Immunoflow, 199 00 Prague, Czech Republic
3Laboratory for Artherosclerosis Research, Institute for Clinical and Experimental Medicine, 140 21 Prague, Czech Republic
4Laboratory of Cellular and Molecular Immunology, Institute of Microbiology, ASCR, 142 00 Prague, Czech Republic
2Immunoflow, 199 00 Prague, Czech Republic
3Laboratory for Artherosclerosis Research, Institute for Clinical and Experimental Medicine, 140 21 Prague, Czech Republic
4Laboratory of Cellular and Molecular Immunology, Institute of Microbiology, ASCR, 142 00 Prague, Czech Republic
Abstract
Background. Food protein-induced proctitis/proctocolitis (FPIP) is the most common noninfectious colitis in children in the first year of life. Along with the overall clinical symptoms, diarrhoea and rectal bleeding are the main manifestations of the disease.
FoxP3 Tregs Response to Sublingual Allergen Specific Immunotherapy in Children Depends on the Manifestation of Allergy
Journal of Immunology Research
Volume 2015 (2015), Article ID 731381, 7 pages
http://dx.doi.org/10.1155/2015/731381
Research Article
Anna Stelmaszczyk-Emmel,1 Anna Zawadzka-Krajewska,2 Eliza Głodkowska-Mrówka,1 and Urszula Demkow1
1Department of Laboratory Diagnostics and Clinical Immunology of Developmental Age, Medical University of Warsaw, Poland
2Department of Pediatric Pneumonology and Allergology, Medical University of Warsaw, Poland
2Department of Pediatric Pneumonology and Allergology, Medical University of Warsaw, Poland
Abstract
Over the last decades allergic diseases has become a major health problem worldwide. The only specific treatment to date is allergen specific immunotherapy (ASIT). Although it was shown that ASIT generates allergen-tolerant T cells, detailed mechanism underlying its activity is still unclear and there is no reliable method to monitor its effectiveness. The aim of our study was to evaluate ASIT influence on the frequency of forkhead box P3 (FoxP3) Tregs in allergic children with various clinical manifestations.
September 18, 2015
Review on immunotherapy in airway allergen sensitised patients.
Neth J Med. 2015 Jul;73(6):263-9.
van der Valk JP1, de Jong NW, Gerth van Wijk R.
Abstract
Towards a Clinical Decision Support System for Drug Allergy Management: Are Existing Drug Reference Terminologies Sufficient for Identifying Substitutes and Cross-Reactants?
William Ogallo, Andrew S. Kanter
1088 - 1088
10.3233/978-1-61499-564-7-1088
Abstract
Drug allergy cross-reactivity checking is an important component of electronic health record systems. Currently, a single, open-source medication dictionary that can provide this function does not exist. In this study, we assessed the feasibility of using RxNorm and NDF-RT (National Drug File – Reference Terminology) for allergy management decision support.
Allergy Risk Finder: Hypothesis Generation System for Allergy Risks via Web Service
Eiji Aramaki, Shuko Shikata, Eriko Watabe, Mai Miyabe, Yasuyuki Usuda, Satsuki Ayaya, Shinichiro Kumagaya
1113 - 1113
10.3233/978-1-61499-564-7-1113
Abstract
This study's aim was to build a web service that automatically collects and tests hypotheses for possible allergy risks.
An eHealth Approach to Reporting Allergic Reactions to Food and Closing the Knowledge Gap
Christopher Munro, Aida Semic-Jusufagic, Katarzyna Pyrz, Philip Couch, Audrey Dunn-Galvin, Niels Peek, Marina Themis, Clare Mills, Iain Buchan, Jonathan Hourihane, Angela Simpson
320 - 324
10.3233/978-1-61499-564-7-320
Abstract
There is an important knowledge gap in food allergy management in understanding the factors that determine allergic reactions to food, in gathering objective reports of reactions in real time, and in accessing patients' reaction-histories during consultations.
September 17, 2015
To Assess the Quality of Life in Patients Suffering from Allergic Rhinitis
Journal of Basic & Applied Sciences- Medical Sciences Pages 501-506
Nikhil Sharma, Prithpal S. Matreja, Monika Gupta, Vipan Gupta,Manish Gupta and Ashwani K. Gupta
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Abstract: Background: Allergic Rhinitis (AR) associated with impairments in patients day-to-day functioning at home and work is a global health problem. It’s associated with sleep disorders, emotional problems, impairment in activities, and social functioning. However, it’s not known to what extent quality of life (QOL) scores, work impairment, or sleep is altered in Indian setup hence, this study was designed to assess the quality of life of patients suffering from allergic rhinitis.
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