Another Frontier in Microbiome Research: Preterm Birth

 JAMA. Published online September 29, 2015. doi:10.1001/jama.2015.11563

FREE ONLINE FIRST

Julie A. Jacob, MA

Article

After Elise and Todd Jackson’s son, Elijah, was born 14 weeks prematurely in 2002, he spent 7 months in the neonatal intensive care unit at Rockford Memorial Hospital in north central Illinois. Although Elijah is now an active and healthy 13-year-old, because of medical problems stemming from his prematurity, as an infant he was given a feeding tube, underwent surgery to close the duct between his pulmonary artery and aorta, and needed a tracheotomy to help him breathe.

Application of nitric oxide measurements in clinical conditions beyond asthma

Andrei Malinovschi^1*, Dora Ludviksdottir², Ellen Tufvesson³, Giovanni Rolla⁴, Leif Bjermer³, Kjell Alving⁵ and Zuzana Diamant^3,6,7,8

¹Department of Medical Sciences: Clinical Physiology, Uppsala University, Uppsala, Sweden; ²Department of Respiratory Medicine and Sleep, Landspitali University Hospital, Reykjavik, Iceland; ³Department of Respiratory Medicine and Allergology, Institute for Clinical Science, Lund University, Lund, Sweden; ⁴Department of Medical Sciences, Allergology and Clinical Immunology, University of Torino, Torino, Italy; ⁵Department of Women’s and Children’s Health, Uppsala University, Uppsala, Sweden; ⁶Department of Clinical Pharmacy & Pharmacology, University Medical Centre Groningen, Groningen, The Netherlands; ⁷Department of General Practice, University Medical Centre Groningen, Groningen, The Netherlands; ⁸QPS Netherlands, Groningen, The Netherlands

ABSTRACT

Fractional exhaled nitric oxide (FeNO) is a convenient, non-invasive method for the assessment of active, mainly Th2-driven, airway inflammation, which is sensitive to treatment with standard anti-inflammatory therapy. Consequently, FeNO serves as a valued tool to aid diagnosis and monitoring in several asthma phenotypes.

Health-related quality of life in patients with primary immunodeficiency disease

Review

Fonda Jiang^13*, Troy R. Torgerson¹² and Andrew G. Ayars¹²

Allergy, Asthma & Clinical Immunology 2015, 11:27  doi:10.1186/s13223-015-0092-y

Abstract

Primary immunodeficiency disease (PIDD) with hypogammaglobulinemia is characterized by recurrent and severe bacterial infections and IgG replacement is the standard of care in many of these patients. Health-related quality of life (HRQOL) is becoming increasingly recognized as a factor that affects patient well-being and treatment preferences. In an effort to better understand what factors affect HRQOL in patients with PIDD, we reviewed the published literature that used standardized instruments for the measurement of HRQOL.

Airway Smooth Muscle Phenotypes in Asthma - PartnersAsthmaCenter

Airway Smooth Muscle Phenotypes in Asthma

Xingbin Ai, Ph.D

2015.09.11 PHS Asthma Grand Rounds

Better management of cow's milk allergy using a very low dose food challenge test: A retrospective study

Allergology International
Vol. 64 (2015) No. 3 p. 272-276

Language:      English     Japanese   

http://doi.org/10.1016/j.alit.2015.04.002

ORIGINAL ARTICLE

Better management of cow's milk allergy using a very low dose food challenge test: A retrospective study

Yu Okada¹⁾, Noriyuki Yanagida¹⁾, Sakura Sato²⁾, Motohiro Ebisawa²⁾

1) Department of Pediatrics, Sagamihara National Hospital 2) Department of Allergy, Clinical Research Center for Allergology and Rheumatology, Sagamihara National Hospital

• Abstracts
• References(25)

Background: Low dose reactive cow's milk (CM) allergic children are at high risk of persistent CM allergy and a positive oral food challenge (OFC). The present study aimed to evaluate if the results of a very low dose (VL) OFC with these children contributes to better management of CM allergy.

Menopause as a predictor of new-onset asthma: A longitudinal Northern European population study

Kai Triebner, MSc

,

 Ane Johannessen, PhD

,

 Luca Puggini, MSc

,

 Bryndís Benediktsdóttir, MD, PhD

,

Randi J. Bertelsen, PhD

,

 Ersilia Bifulco, PhD

,

 Shyamali C. Dharmage, MD, PhD

,

 Julia Dratva, MD, MPH

,

Karl A. Franklin, MD, PhD

,

 Thórarinn Gíslason, MD, PhD

,

 Mathias Holm, MD, PhD

,

 Deborah Jarvis, MD, PhD

,

 Bénédicte Leynaert, PhD

,

 Eva Lindberg, MD, PhD

,

 Andrei Malinovschi, MD, PhD

,

 Ferenc Macsali, MD, PhD

,

 Dan Norbäck, MD, PhD

,

 Ernst R. Omenaas, MD, PhD

,

 Francisco J. Rodríguez, PhD

,

 Eirunn Saure, MD

,

 Vivi Schlünssen, MD, PhD

,

 Torben Sigsgaard, MD, PhD

,

 Trude D. Skorge, MD, PhD

,

 Gunilla Wieslander, MD, PhD

,

 Elisabeth Zemp, MD, PhD

,

 Cecilie Svanes, MD, PhD

,

 Steinar Hustad, MD, PhD

,

Francisco Gómez Real, MD, PhD

Publication stage: In Press Corrected Proof

Open Access

DOI: http://dx.doi.org/10.1016/j.jaci.2015.08.019   Open access funded by the Author(s)

Article Info

• Abstract
• Full Text
• Images
• References

Background

There is limited and conflicting evidence on the effect of menopause on asthma.

Objectives

We sought to study whether the incidence of asthma and respiratory symptoms differ by menopausal status in a longitudinal population-based study with an average follow-up of 12 years.

Homo Nodus: Preparing For The Next Stage Of The Internet Of Things In Medical Education

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Original Article

K Masters

Abstract

The Internet of Things (IoT) is upon us.  The exact impact of the IoT on medical education is, as yet, unknown, but we do know that it promises great potential to be harnessed.

Dendritic cells revisited in human allergic rhinitis and asthma

Accepted Article (Accepted, unedited articles published online and citable. The final edited and typeset version of record will appear in future.)

1. Antoine Froidure^1,2,†, 
2. Chong Shen^1,†and
3. Charles Pilette^1,2,*

DOI: 10.1111/all.12770

Abstract

The role of dendritic cells (DCs) in airway allergy has been studied for 15 years, recent data has highlighted the cross-talk between with airway epithelial cells and environmental factors (allergens, virus) during the inception and exacerbation of allergic asthma.