November 10, 2015

360 degree perspective on allergic rhinitis management in Italy: a survey of GPs, pharmacists and patients

Research

Open Access

G. Walter Canonica1*Massimo Triggiani2 and GianEnrico Senna3
The electronic version of this article is the complete one and can be found online at:http://www.clinicalmolecularallergy.com/content/13/1/25
Abstract
Background
General practitioners (GPs), community pharmacists and allergic rhinitis (AR) patients in Italy were surveyed in order to gain insight from all three perspectives into the diagnosis, management and burden of AR in Italy.

November 9, 2015

Appropriateness of epinephrine use in ED patients with anaphylaxis

Anaphylaxis is a potentially fatal allergic reaction that is most commonly treated in the emergency department (ED). Epinephrine is the treatment of choice for anaphylaxis.

November 4, 2015

Celiac disease and non-celiac gluten sensitivity

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BMJ : British Medical Journal
 2015 Oct 5;351:h4347. doi: 10.1136/bmj.h4347.

Abstract

Celiac disease is a multisystem immune based disorder that is triggered by the ingestion of gluten in genetically susceptible individuals. The prevalence of celiac disease has risen in recent decades and is currently about 1% in most Western populations.

November 2, 2015

A common language to assess allergic rhinitis control: results from a survey conducted during EAACI 2013 Congress

Research

Open Access

Peter W. Hellings12*Antonella Muraro3Wytske Fokkens2Joaquim Mullol4Claus Bachert5G. Walter Canonica6,David Price7Nikos Papadopoulos8Glenis Scadding9Gerd Rasp10Pascal Demoly11Ruth Murray12 and Jean Bousquet13141516
Abstract
Background
The concept of control is gaining importance in the field of allergic rhinitis (AR), with a visual analogue scale (VAS) score being a validated, easy and attractive tool to evaluate AR symptom control. The doctors’ perception of a VAS score as a good tool for evaluating AR symptom control is unknown, as is the level of AR control perceived by physicians who treat patients.

October 30, 2015

Structural similarities of human & mammalian lipocalins, and their function in innate immunity and allergy

      1. E Jensen-Jarolim, 
      2. Luis F Pacios, 
      3. R Bianchini, 
      4. G Hofstetter and
      5. F Roth-Walter
        1. Abstract

          Owners and their domestic animals via skin shedding and secretions, mutually exchange microbiomes, potential pathogens and innate immune molecules. Among the latter especially lipocalins are multifaceted: they may have an immunomodulatory function and, furthermore, they represent one of the most important animal allergen families.

The 2015 IUIS Phenotypic Classification for Primary Immunodeficiencies


 2015 Oct 7. [Epub ahead of print]

Open Access

  • Aziz Bousfiha, 
  • Leïla Jeddane
  • Waleed AlHerz
  • Fatima Ailal
  • JeanLaurent Casanova
  • ,Talal Chatila
  • Mary Ellen Conley
  • Charlotte Cunningham‐Rundles
  • Amos Etzioni
  • Abstract

    There are now nearly 300 single-gene inborn errors of immunity underlying phenotypes as diverse as infection, malignancy, allergy, auto-immunity, and auto-inflammation. For each of these five categories, a growing variety of phenotypes are ascribed to Primary Immunodeficiency Diseases (PID), making PIDs a rapidly expanding field of medicine.

    From bronchiolitis guideline to practice: A critical care perspective

    James A Lin, Andranik Madikians, Division of Pediatric Critical Care Medicine, Department of Pediatrics, Mattel Children’s Hospital UCLA, University of California, Los Angeles, CA 90095, United States

    Acute viral bronchiolitis is a leading cause of admission to pediatric intensive care units, but research on the care of these critically ill infants has been limited. Pathology of viral bronchiolitis revealed respiratory obstruction due to intraluminal debris and edema of the airways and vasculature. This and clinical evidence suggest that airway clearance interventions such as hypertonic saline nebulizers and pulmonary toilet devices may be of benefit, particularly in situations of atelectasis associated with bronchiolitis.