IgE serum concentration against airborne fungi in children with respiratory allergies

RESEARCH OPEN ACCESS

Geusa Felipa de Barros Bezerra, Denise Maria Costa Haidar, Marcos Antonio Custódio Neto da Silva, Walbert Edson Muniz Filho, Ramon Moura dos Santos, Ivone Garros Rosa, Graça Maria de Castro Viana, Luís Zaror and Maria do Desterro Soares Brandão Nascimento

Allergy, Asthma & Clinical Immunology 2016 12:18 DOI: 10.1186/s13223-016-0128-y

Abstract

Background

To evaluate total and specific E immunoglobulin (IgE) antibody concentrations in underage subjects with respiratory allergic diseases.

Methods

This study was a transversal-type study in 100 underage subjects between 4 and 14 years old, with asthma and/or allergic rhinitis. Total and specific IgE were quantified for airborne fungi in the city of São Luís, Maranhão, Brazil. Five distinct regions—North, South, Center, East and West—were selected so fungi could be collected monthly for 1 year.

Differential gene network analysis for the identification of asthma-associated therapeutic targets in allergen-specific T-helper memory responses

Niamh M. Troy, Elysia M. Hollams, Patrick G. Holt and Anthony Bosco
BMC Medical Genomics BMC series – open, inclusive and trusted20169:9 DOI: 10.1186/s12920-016-0171-z

Abstract

Background
Asthma is strongly associated with allergic sensitization, but the mechanisms that determine why only a subset of atopics develop asthma are not well understood. The aim of this study was to test the hypothesis that variations in allergen-driven CD4 T cell responses are associated with susceptibility to expression of asthma symptoms.

Need for medication and stuffy nose predict the severity of allergic rhinitis

Asia Pac Allergy. 2016 Apr;6(2):133-135. English. Taneli Salo,1 Sirpa Peura,2 Johanna Salimäki,2 Paula Maasilta,3 Tari Haahtela,1 and Paula Kauppi To the Editor, As a part of the Finnish Allergy Programme 2008-2018 [1], we surveyed patients to assess allergic rhinitis symptoms, the use of medications and health care services in Finland. The study cohort consisted of 1,114 patients aged 5–75 years (mean age, 47 years; 72% females) who obtained asthma or allergy medication from 382 Finnish pharmacies (47% of all 812 pharmacies) across the country. The participants were the first consecutive 1–5 clients per pharmacy purchasing asthma or allergy medication during 1 week period in September 2010 [2]. Participants (or their parents for those 5 to 16 years old) completed a self-administered questionnaire to assess their allergy symptoms, use of medications, health care service use (number of hospital admissions and physician appointments).

A review on the role of moisturizers for atopic dermatitis

Asia Pac Allergy. 2016 Apr;6(2):120-8

Giam YC, Hebert AA, Dizon MV, Van Bever H, Tiongco-Recto M, Kim KH, Soebono H, Munasir Z, Diana IA, Luk DC

Abstract

Effective management of atopic dermatitis (AD) involves the treatment of a defective skin barrier. Patients with AD are therefore advised to use moisturizers regularly. To date, there are few comparative studies involving moisturizers in patients with AD, and no classification system exists to objectively determine which types of moisturizers are best suited to specific AD phenotypes. With this in mind, a group of experts from allergy and immunology, adult and pediatric dermatology, and pediatrics centers within Southeast Asia met to review current data and practice, and to develop recommendations regarding the use of moisturizers in patients with AD within the Asia-Pacific region.

Mometasone furoate nasal spray: a systematic review

REVIEW

 

OPEN ACCESS

• Desiderio PassaliEmail author,
• Maria Carla Spinosi,
• Anna Crisanti and
• Luisa Maria Bellussi

Multidisciplinary Respiratory Medicine201611:18

DOI: 10.1186/s40248-016-0054-3

Abstract

The inflammatory diseases of the nose, rhino-pharynx and paranasal sinuses (allergic and non allergic rhinitis, NARES; rhinosinusitis with/without nasal polyposis, adenoidal hypertrophy with/without middle ear involvement) clinically manifest themselves with symptoms and complications severely affecting quality of life and health care expenditure.

Intranasal administration of corticosteroids, being fast, simple, and not requiring cooperation, is the preferred way to treat the patients, to optimize their quality of life, at the same time minimizing the risk of exacerbations and complications.

World Asthma Day 2016 Infographic

Wad 2016 infographic 

Effectiveness of the Polish program for the treatment of severe allergic asthma with omalizumab: a single-center experience

Izabela Kupryś-Lipińska , Paweł Majak, Joanna Molinska and Piotr Kuna

BMC Pulmonary MedicineBMC series – open, inclusive and trusted201616:61

DOI: 10.1186/s12890-016-0224-2

Abstract

Background

A national program for the treatment of severe allergic (IgE-dependent) asthma with omalizumab (OMA) was implemented in Poland in 2013. This observational study evaluated the effectiveness of the Polish OMA program and monitored asthma control after treatment discontinuation.

Childhood asthma and physical activity: a systematic review with meta-analysis and Graphic Appraisal Tool for Epidemiology assessment

Lene Lochte, Kim G. Nielsen, Poul Erik Petersen and Thomas A. E. Platts-MillsBMC PediatricsBMC series – open, inclusive and trusted201616:50

DOI: 10.1186/s12887-016-0571-4

Open Peer Review reports

Abstract

Background

Childhood asthma is a global problem affecting the respiratory health of children. Physical activity (PA) plays a role in the relationship between asthma and respiratory health. We hypothesized that a low level of PA would be associated with asthma in children and adolescents. The objectives of our study were to (1) summarize the evidence available on associations between PA and asthma prevalence in children and adolescents and (2) assess the role of PA in new-onset or incident asthma among children and adolescents.