August 22, 2016

Exogenous lipid pneumonia related to long-term use of Vicks VapoRub® by an adult patient: a case report

 
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Abstract
Background
Use of petroleum-based over the counter remedies such as Vicks VapoRub to alleviate symptoms of rhinitis is common and can be effective, but carries under-appreciated risks of adverse side effects. In this case report we highlight Exogenous Lipoid Pneumonia (ELP), an uncommon condition that results from accumulation of exogenous lipids in the alveoli, as an adverse side effect of long-term Vicks VapoRub use.

August 21, 2016

Reduced work/academic performance and quality of life in patients with allergic rhinitis and impact of allergen immunotherapy

  • A. Roger,
  • E. Arcalá Campillo,
  • M. C. Torres,
  • C. Millan,
  • I. Jáuregui,
  • E. Mohedano,
  • S. Liñan,
  • P. Verdu,
  • N. Rubira,
  • M. Santaolalla,
  • P. González,
  • A. Orovitg and
  • E. VillarrubiaEmail author
Abstract
Background
Allergic rhinitis (AR) is characterised by burdensome nasal and/or ocular symptoms. This inflammatory disease can be debilitating and thus result in considerable health-related and economic consequences.
Methods
In a cross-sectional study, adult subjects with AR (N = 683) completed three allergy-specific questionnaires that assessed the impact of AR on the work/academic performance, daily activities, health-related quality of life (HRQOL), and satisfaction with allergen immunotherapy (AIT).

Specific immunotherapy ameliorates ulcerative colitis


  • Min Cai,
  • Lu Zeng,
  • Lin-Jing Li,
  • Li-Hua Mo,
  • Rui-Di Xie,
  • Bai-Sui Feng,
  • Peng-Yuan Zheng,
  • Zhi-Gang Liu,
  • Zhan-Ju Liu
  • and
  • Ping-Chang Yang
  • Background
    Hypersensitivity reaction to certain allergens plays a role in the pathogenesis of inflammatory bowel disease (IBD). This study aims to observe the effect of specific immunotherapy in a group of IBD patients.
    Methods
    Patients with both ulcerative colitis (UC) and food allergy were recruited into this study. Food allergy was diagnosed by skin prick test and serum specific IgE. The patients were treated with specific immunotherapy (SIT) and Clostridium butyricum (CB) capsules.

    August 20, 2016

    The Urban-Rural Gradient In Asthma: A Population-Based Study in Northern Europe

    Logo of ijerphMDPI Open Access JournalsMDPI Open Access JournalsThis articleThis JournalInstructions for authorsAdd your e-mail address to receive forthcoming issues of this journal
    . 2016 Jan; 13(1): 93.
    Published online 2015 Dec 30. doi:  10.3390/ijerph13010093
    PMCID: PMC4730484

    Abstract

    The early life environment appears to have a persistent impact on asthma risk. We hypothesize that environmental factors related to rural life mediate lower asthma prevalence in rural populations, and aimed to investigate an urban-rural gradient, assessed by place of upbringing, for asthma.

    Pilot study: assessing the clinical diagnosis of allergy in atopic children using a microarray assay in addition to skin prick testing and serum specific IgE

     
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    • Ru-Xin FoongEmail author,
    • Graham Roberts,
    • Adam Tobias Fox and
    • George du Toit
    Abstract
    Background
    Children with atopic dermatitis (AD) are at risk of developing allergy. Alongside clinical history, testing modalities include skin prick tests (SPT), specific immunoglobulin-E (sp-IgE) and recently, microarray assays. The aim of this pilot study was to assess current tests and the ISAC sIgE-112 system in the diagnosis of food and aeroallergen allergy.

    August 18, 2016

    Medical adherence to intranasal corticosteroids in adult patients


    Available online 20 July 2016

    Combination of specific allergen and probiotics induces specific regulatory B cells and enhances specific immunotherapy effect on allergic rhinitis



    Ling-Zhi Xu1,*, Li-Tao Yang1,2,*, Shu-Qi Qiu1,2,*, Gui Yang1,2, Xiang-Qian Luo3, Bei-Ping Miao4, Xiao-Rui Geng1,2, Zhi-Qiang Liu1,2, Jun Liu5, Zhong Wen6, Shuai Wang1,2, Huan-Ping Zhang7, Jing Li8, Zhi-Gang Liu1, Hua-Bin Li3 and Ping-Chang Yang1
    DOI: 10.18632/oncotarget.10946



    ABSTRACT
    The therapeutic efficacy of allergen specific immunotherapy (SIT) on allergic diseases is to be improved. Probiotics can regulate immune response. This study aims to promote the effect of SIT on allergic rhinitis (AR) by co-administration with Clostridium butyricum(Cb). In this study, patients with AR sensitized to mite allergens were enrolled to this study, and treated with SIT or/and Cb. The therapeutic efficacy was evaluated by the total nasal symptom scores (NSS), medication scores, serum specific IgE levels and T helper (Th)2 cytokine levels. The improvement of immune regulation in the AR patients was assessed by immunologic approaches.