February 15, 2017

Self-assessment of Allergic Rhinitis and Asthma (SACRA) Questionnaire-based Allergic Rhinitis Treatment Improves Asthma Control in Asthmatic Patients with Allergic Rhinitis

Internal Medicine
Vol. 56 (2017) No. 1 p. 31-39

Language: 
http://doi.org/10.2169/internalmedicine.56.7251
ORIGINAL ARTICLES

Objective This study was conducted to investigate whether the add-on treatment of allergic rhinitis (AR) based on the Self-assessment of Allergic Rhinitis and Asthma (SACRA) questionnaire for assessing AR control improves both AR and asthma control in asthmatic patients with AR.
Methods This multi-center prospective study was performed in Nagano prefecture, Japan. Two hundred five asthmatic patients and 23 respiratory physicians participated in the study. We administered add-on AR treatments based on the results of the SACRA questionnaire. After the first SACRA questionnaire, 67 asthmatic patients agreed to receive an add-on AR treatment. Three months after the AR treatment, a secondary SACRA questionnaire, asthma control test (ACT), and pulmonary function tests were performed.

February 13, 2017

Biomarkers for Monitoring Clinical Efficacy of Allergen Immunotherapy for Allergic Rhinoconjunctivitis and Allergic Asthma: an EAACI Position Paper.

 2017 Feb 2. doi: 10.1111/all.13138. [Epub ahead of print]

Abstract

Allergen immunotherapy (AIT) is an effective treatment for allergic rhinoconjunctivitis (AR) with or without asthma (1-12). AIT has disease modifying properties and confers long-term clinical benefit after cessation of treatment (6, 7, 13-17). AIT is routinely used in daily practice and can be administered either subcutaneously (SCIT) or sublingually (SLIT) (3-12).

February 10, 2017

High-dose anti-histamine use and risk factors in children with urticaria


Pınar Uysal 1 ,  Sibelnur Avcil 2 ,  Duygu Erge 1 
1 Adnan Menderes Üniversitesi Tıp Fakültesi, Çocuk Allerji ve Klinik İmmunoloji Bilim Dalı, Aydın, Türkiye 
2 Adnan Menderes Üniversitesi Tıp Fakültesi, Çocuk ve Ergen Ruh Sağlığı ve Hastalıkları Anabilim Dalı, Aydın, Türkiye 


Abstract
Aim: The drugs of choice in the treatment of urticaria in children are H1-antihistamines. The aim of the study was to evaluate children with urticaria and define risk factors for requirement of high-dose H1-antihistamines in children with urticaria.

February 9, 2017

Revisiting Type 2-high and Type 2-low airway inflammation in asthma: current knowledge and therapeutic implications

  • DOI: 10.1111/cea.12880View/save citation 
  • Summary
    Asthma is a complex respiratory disorder characterized by marked heterogeneity in individual patient disease triggers and response to therapy. Several asthma phenotypes have now been identified, each defined by a unique interaction between genetic and environmental factors, including inflammatory, clinical and trigger-related phenotypes.

Subtypes of asthma based on asthma control and severity: a latent class analysis

 
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  • Elina M. S. Mäkikyrö,
  • Maritta S. Jaakkola and
  • Jouni J. K. JaakkolaEmail author
Abstract
Background
Asthma subtyping is a complex new field of study. Usually both etiological and outcome factors of asthma have been used simultaneously for subtyping thus making the interpretation of the results difficult. Identification of subtypes of asthma based on questionnaire data only will be useful for both treatment of asthma and for research. Our objective was to identify asthma subtypes that capture both asthma control and severity based on easily accessible variables.