Findings from an Online Survey Assessing the Burden and Management of Seasonal Allergic Rhinoconjunctivitis in US Patients

May–June, 2017Volume 5, Issue 3, Pages 779–789.e6

Eli O. Meltzer, MDCorrespondence information about the author MD Eli O. MeltzerEmail the author MD Eli O. Meltzer

, 

Judith Rosen Farrar, PhD

, 

Cary Sennett, MD, PhD

Open Access

PlumX Metrics

DOI: http://dx.doi.org/10.1016/j.jaip.2016.10.010

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Background

Seasonal allergic rhinoconjunctivitis (SARC) affects ≥16% of the US population annually. Telephone and in-office surveys have demonstrated negative effects of allergic rhinitis (AR) symptoms on sleep, daily activities, productivity, concentration, and emotions.

Abridged version of the AWMF guideline for the medical clinical diagnostics of indoor mould exposure

• Springer Open Choice
• PMC5533814

Allergo Journal International

Allergo J Int. 2017; 26(5): 168–193.

Published online 2017 Feb 28. doi:  10.1007/s40629-017-0013-3

PMCID: PMC5533814

S2K Guideline of the German Society of Hygiene, Environmental Medicine and Preventive Medicine (GHUP) in collaboration with the German Association of Allergists (AeDA), the German Society of Dermatology (DDG), the German Society for Allergology and Clinical Immunology (DGAKI), the German Society for Occupational and Environmental Medicine (DGAUM), the German Society for Hospital Hygiene (DGKH), the German Society for Pneumology and Respiratory Medicine (DGP), the German Mycological Society (DMykG), the Society for Pediatric Allergology and Environmental Medicine (GPA), the German Federal Association of Pediatric Pneumology (BAPP), and the Austrian Society for Medical Mycology (ÖGMM)

Gerhard A. Wiesmüller,1,2 Birger Heinzow,3 Ute Aurbach,4 Karl-Christian Bergmann,5 Albrecht Bufe,6 Walter Buzina,7Oliver A. Cornely,8 Steffen Engelhart,9 Guido Fischer,10 Thomas Gabrio,11 Werner Heinz,12 Caroline E. W. Herr,13,14Jörg Kleine-Tebbe,15 Ludger Klimek,16 Martin Köberle,17 Herbert Lichtnecker,18 Thomas Lob-Corzilius,19 Rolf Merget,20 Norbert Mülleneisen,21 Dennis Nowak,22 Uta Rabe,23 Monika Raulf,20 Hans Peter Seidl,24 Jens-Oliver Steiß,25,26 Regine Szewszyk,27 Peter Thomas,28 Kerttu Valtanen,27 and Julia Hurraß2

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Abstract

This article is an abridged version of the AWMF mould guideline “Medical clinical diagnostics of indoor mould exposure” presented in April 2016 by the German Society of Hygiene, Environmental Medicine and Preventive Medicine (Gesellschaft für Hygiene, Umweltmedizin und Präventivmedizin, GHUP), in collaboration with the above-mentioned scientific medical societies, German and Austrian societies, medical associations and experts.

DRESS: What does the emergency physician need to know?

Authors: Matthew Nemero, DO (Resident Physician, SAUSHEC) and Joshua Oliver, MD (EM Attending Physician, SAUSHEC) // Edited by: Alex Koyfman, MD (@EMHighAK) and Brit Long, MD (@long_brit)

Case

A 15-year-old male patient presents to your emergency department with his family complaining of a fever for 3 days and a rash that started on his face and chest that has been spreading for 3 days. Past medical history is significant for 3 ED visits in the past 90 days and a new diagnosis of epilepsy for which he recently started seeing a neurologist and was placed on phenytoin 3 weeks ago.

Vitals: HR 84, BP 122/74, RR 12, T 38.8 (101.8F), SpO2 99% RA

• On physical exam, you palpate enlarged and tender cervical and axillary lymph nodes.
• You note the generalized rash shown below. It does not involve the oral mucosa.

FULL TEXT

James Verbsky, MD, PhD describes the uses of flow cytometry for the diagnosis of primary immunodeficiency.

ACAAICOLA

Bacterial d-amino acids suppress sinonasal innate immunity through sweet taste receptors in solitary chemosensory cells

Sci. Signal. Vol 10, Issue 495 05 September 2017

1. Robert J. Lee1,2,*, 
2. Benjamin M. Hariri1, 
3. Derek B. McMahon1, 
4. Bei Chen1, 
5. Laurel Doghramji1, 
6. Nithin D. Adappa1, 
7. James N. Palmer1, 
8. David W. Kennedy1, 
9. Peihua Jiang3, 
10. Robert F. Margolskee3, and 
11. Noam A. Cohen1,3,4,*

+ See all authors and affiliations

Sci. Signal.  05 Sep 2017:
Vol. 10, Issue 495, eaam7703
DOI: 10.1126/scisignal.aam7703

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The sweet taste of bacteria

Stimulation of the sweet taste receptor (T1R) in solitary chemosensory cells of the upper respiratory epithelium inhibits the release of antimicrobial peptides by neighboring epithelial cells. In addition to being activated by various sugars, T1R can also be activated by some D-amino acids.

Asthma Control and Sputum Eosinophils: A Longitudinal Study in Daily Practice

September–October, 2017Volume 5, Issue 5, Pages 1335–1343.e5

Sophie F. Demarche, MPharmCorrespondence information about the author MPharm Sophie F. DemarcheEmail the author MPharm Sophie F. Demarche

, 

Florence N. Schleich, MD, PhD

, 

Virginie A. Paulus, MLT

, 

Monique A. Henket, MLT

, 

Thierry J. Van Hees, MPharm, PhD

, 

Renaud E. Louis, MD, PhD

Open Access

PlumX Metrics

DOI: http://dx.doi.org/10.1016/j.jaip.2017.01.026

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Background

Longitudinal trials have suggested that asthma control may be influenced by fluctuations in eosinophilic inflammation. This association has however never been confirmed in daily practice.

Fatal Anaphylaxis: Mortality Rate and Risk Factors

September–October, 2017Volume 5, Issue 5, Pages 1169–1178

Paul J. Turner, MD, PhD

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Elina Jerschow, MD

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Thisanayagam Umasunthar, MD

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Robert Lin, MD

, 

Dianne E. Campbell, MD, PhD

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Robert J. Boyle, MB, ChB, PhDCorrespondence information about the author MB, ChB, PhD Robert J. BoyleEmail the author MB, ChB, PhD Robert J. Boyle

Open Access

DOI: http://dx.doi.org/10.1016/j.jaip.2017.06.031

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Article Info

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Up to 5% of the US population has suffered anaphylaxis. Fatal outcome is rare, such that even for people with known venom or food allergy, fatal anaphylaxis constitutes less than 1% of total mortality risk. The incidence of fatal anaphylaxis has not increased in line with hospital admissions for anaphylaxis. Fatal drug anaphylaxis may be increasing, but rates of fatal anaphylaxis to venom and food are stable.

A survey on the perception of allergy specialists about the reimbursed grass pollen tablets for seasonal allergic rhinitis in Italy

Clinical and Molecular Allergy

RESEARCH

 

OPEN ACCESS

Ilaria Massaro, Oliviero Rossi, Cristoforo Incorvaia and Carlo Lombardi

Clinical and Molecular Allergy201715:15

https://doi.org/10.1186/s12948-017-0071-6

Abstract

Background

Sublingual immunotherapy (SLIT) is a feasible option to classical subcutaneous immunotherapy to treat respiratory allergy and is increasingly prescribed in Europe. However, the lack of reimbursement may limit its prescription. In 2015, the 5-grass pollen tablets was authorized by the European Medicine Agency to treat grass-pollen induced rhinitis and was approved in Italy for full reimbursement. We evaluated the opinions of allergy specialists after the availability of the reimbursed 5-grass pollen tablets.