Examining the association between maternal atopy and birth outcomes using a retrospective cohort in the southeastern region of the USA

Public health

Abstract

Objective To assess birth outcomes in primiparous women with diagnosis of non-asthmatic atopy (NAA). Researchers hypothesised that women with NAA would have reduced the risk of adverse birth outcomes compared with women without NAA. NAA is defined as having allergic rhinitis and/or atopic dermatitis.

Setting Women were mostly treated in primary care settings in South Carolina, USA.

Reference values for spirometry in elderly individuals: a cross-sectional study of different reference equations

Multidisciplinary Respiratory Medicine

Original research article

Open Access

• Joana BeloEmail author,
• Teresa Palmeiro,
• Iolanda Caires,
• Ana L. Papoila,
• Marta Alves,
• Pedro Carreiro-Martins,
• Maria A. Botelho and
• Nuno Neuparth

Multidisciplinary Respiratory Medicine201813:4

https://doi.org/10.1186/s40248-017-0112-5

Abstract

Background

Spirometry is the single most important test for the evaluation of respiratory function. The results are interpreted by comparing measured data with predicted values previously obtained from a reference population. Reference equations for spirometry have been discussed previously.

The Diagnostic Accuracy of Fractional Exhaled Nitric Oxide Testing in Asthma: A Systematic Review and Meta-analyses

Zhen Wang, PhD

, 

Paolo T. Pianosi, MD

, 

Karina A. Keogh, MD

, 

Feras Zaiem, MD

, 

Mouaz Alsawas, MD, MSc

, 

Fares Alahdab, MD

, 

Jehad Almasri, MD

, 

Khaled Mohammed, MBBCh

, 

Laura Larrea-Mantilla, MD

, 

Wigdan Farah, MBBS

, 

Lubna Daraz, PhD

, 

Patricia Barrionuevo, MD

, 

Allison S. Morrow, BA

, 

Larry J. Prokop, MLS

, 

Mohammad Hassan Murad, MD, MPHCorrespondence information about the author MD, MPH Mohammad Hassan MuradEmail the author MD, MPH Mohammad Hassan Murad

DOI: http://dx.doi.org/10.1016/j.mayocp.2017.11.012

                                                         Article Info

• Abstract

• Full Text

• Images
• References
• Supplemental Materials

Audio/Video

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Article Outline

1. Methods
   1. Data Sources and Searches
   2. Study Selection
   3. Data Extraction and Quality Assessment
   4. Main Outcome Measures
   5. Data Synthesis and Analysis
   6. Grading the Quality of Evidence (ie, Certainty in Estimates)
2. Results
   1. Description of the Evidence
   2. Diagnostic Accuracy of FeNO Testing
   3. Subgroup and Sensitivity Analyses
3. Discussion
4. Conclusion
5. Acknowledgments
6. Supplemental Online Material
7. References

Jump to SectionMethods  Data Sources and Searches  Study Selection  Data Extraction and Quality Assessment  Main Outcome Measures  Data Synthesis and Analysis  Grading the Quality of Evidence (ie, Certainty in Estimates)Results  Description of the Evidence  Diagnostic Accuracy of FeNO Testing  Subgroup and Sensitivity AnalysesDiscussionConclusionAcknowledgmentsSupplemental Online MaterialReferences

Effect of air quality alerts on human health: a regression discontinuity analysis in Toronto, Canada

Volume 2, No. 1, e19–e26, January 2018

Open Access

Hong Chen, Qiongsi Li, MMath, Jay S Kaufman, PhD, Jun Wang, MSc, Ray Copes, MD, Yushan Su, PhD, Tarik Benmarhnia, PhD

DOI: http://dx.doi.org/10.1016/S2542-5196(17)30185-7

Summary
Background
Ambient air pollution is a major health risk globally. To reduce adverse health effects on days when air pollution is high, government agencies worldwide have implemented air quality alert programmes. Despite their widespread use, little is known about whether these programmes produce any observable public-health benefits. We assessed the effectiveness of such programmes using a quasi-experimental approach.

Recovery of hypothalamo–pituitary–adrenal axis suppression during treatment with inhaled corticosteroids for childhood asthma

Authors Gangadharan A, McCoy P, Phyo A, McGuigan MP, Dharmaraj P, Ramakrishnan R, McNamara PS, Blair J

Published 15 December 2017 Journal of Asthma and Allergy Volume 2017:10 Pages 317—326

DOI https://doi.org/10.2147/JAA.S142874

Objective: To describe recovery of adrenal insufficiency in asthmatic children treated with inhaled corticosteroids (ICS) and cortisol replacement therapy.

Case report: atypical presentation of vancomycin induced DRESS syndrome: a case report and review of the literature

Case report

Open Access

Open Peer Review

• Olivia Wilcox,
• Mohamed Hassanein,
• John Armstrong and
• Nader KassisEmail author

BMC Pulmonary MedicineBMC series – open, inclusive and trusted201717:217

https://doi.org/10.1186/s12890-017-0564-6

Open Peer Review reports

Abstract

Background

Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe hypersensitivity drug reaction involving the skin and multiple internal organ systems.

Immunosenescence in aging: between immune cells depletion and cytokines up-regulation

Clin Mol Allergy. 2017 Dec 14;15:21. doi: 10.1186/s12948-017-0077-0. eCollection 2017.

Ventura MT1, Casciaro M2, Gangemi S2, Buquicchio R3.

Author information

Abstract

BACKGROUND:

The immunosenescence is a relatively recent chapter, correlated with the linear extension of the average life began in the nineteenth century and still in progress. The most important feature of immunosenescence is the accumulation in the "immunological space" of memory and effector cells as a result of the stimulation caused by repeated clinical and subclinical infections and by continuous exposure to antigens (inhalant allergens, food, etc.).

Feasibility of sustained response through long-term dosing in food allergy immunotherapy

Allergy, Asthma & Clinical Immunology

Research

Open Access

• Sandra Andorf†,
• Monali Manohar†,
• Tina Dominguez,
• Whitney Block,
• Dana Tupa,
• Rohun A. Kshirsagar,
• Vanitha Sampath,
• R. Sharon Chinthrajah† and
• Kari C. Nadeau†Email authorView ORCID ID profile

†Contributed equally

Allergy, Asthma & Clinical Immunology201713:52

https://doi.org/10.1186/s13223-017-0224-7

©  The Author(s) 2017

Abstract

Background

Clinical trials using oral immunotherapy (OIT) for the treatment of food allergies have shown promising results. We previously demonstrated the feasibility of desensitization for up to 5 food allergens simultaneously through OIT. In this observational study, we report the findings of long-term follow-up (LTFU) of the participants treated through a single site OIT phase 1 trial.