Jostein Førsvoll
and
Knut Øymar
BMC Ear, Nose and Throat DisordersBMC series – open, inclusive and trusted201818:3
© The Author(s). 2018
Abstract
Background
Tonsillectomy (TE) or adenotonsillectomy (ATE) may have a beneficial effect on the clinical course in children with the Periodic Fever, Aphthous stomatitis, Pharyngitis and cervical Adenitis (PFAPA) syndrome. However, an immunological reason for this effect remains unknown. This literature review summarizes the current knowledge of the effect of TE or ATE in the PFAPA syndrome.