Gene Therapy - Developments and Future Perspectives

Edited by Chunsheng Kang, ISBN 978-953-307-617-1, Hard cover, 356 pages, Publisher: InTech, Published: June 22, 2011 under CC BY-NC-SA 3.0 license, in subject Medical Genetics
DOI: 10.5772/748

The aim of this book is to cover key aspects of existing problems in the field of development and future perspectives in gene therapy. Contributions consist of basic and translational research, as well as clinical experiences, and they outline functional mechanisms, predictive approaches, patient-related studies and upcoming challenges in this stimulating but also controversial field of gene therapy research. This source will make our doctors become comfortable with the common problems of gene therapy and inspire others to delve a bit more deeply into a topic of interest.

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BOOK CONTENTS

• Chapter 1  New Vectors for Stable and Safe Gene Modificationby Francisco Martín, Karim Benabdellah, Marién Cobo, Pilar Muñoz, Per Anderson and Miguel G. Toscano
• Chapter 2  Gene Therapy Using RNAiby Yu-Lin Yang , Wen- Teng Chang and Yuan-Wei Shih
• Chapter 3  Scalable Technology to Produce Pharmaceutical Grade Plasmid DNA for Gene Therapyby Odalys Ruiz, Miladys Limonta, Jorge Valdés, Martha Pupo and Eduardo Martnez
• Chapter 4  Small interfering RNAs: heralding a new era in gene therapyby Maro Bujak, Ivana Ratkaj, Mirela Baus Lončar, Radan Spaventi and Sandra Kraljevic Pavelic
• Chapter 5  MiRNAs-based Gene Therapy on the Horizon: Novel and Effective Therapeutic Advancementby Mohammad Reza Noori-Daloii and Azim Nejatizadeh
• Chapter 6  Gene Therapy Strategies Incorporating Large Transgenesby Jennifer Johnston, Christopher B. Doering and H. Trent Spencer
• Chapter 7  Recent Advances and Improvements in the Biosafety of Gene Therapyby Jaichandran Sivalingam and Oi Lian Kon
• Chapter 8  Impacts of DNA Microarray Technology in Gene Therapyby Jaleh Barar, Amir Ata Saei and Yadollah Omidi
• Chapter 9  Hopes and Disillusions in Therapeutic Targeting of Intercellular Communication in Cancer.by Mustapha Kandouz
• Chapter 10  Promising Role of Engineered Gene Circuits in Gene Therapyby Wei-Dong Wang and Jinyi Lang
• Chapter 11  Comparison of DNA Delivery and Expression Using Frequently Used Delivery Methodsby Sara Collins, David Morrissey, Simon Rajendran, Garrett Casey, Martina Scallan, Patrick Harrison, Gerald O’Sullivan and Mark Tangney
• Chapter 12  Preclinical and Clinical Prospects of Gene Therapy in Myocardial Infarctionby Saurabh Bharti, Ashok Kumar Sharma, Bhaskar Krishnamurthy and Dharamvir Singh Arya
• Chapter 13  Gene Therapy for Therapeutic Angiogenesisby Rudolf Kirchmair
• Chapter 14  Cancer Gene Therapy- Developments and Future Perspectivesby David Good, Wei Duan, Jozef Anné and Ming Wei
• Chapter 15  Differential Gene Expression and Its Possible Therapeutic Implicationsby Safdar Ali and Sher Ali
• Chapter 16  Engineered Drug Resistant Cell-Mediated Immunotherapyby H.Trent Spencer and Anindya Dasgupta
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  Published online: 22 June, 2011
  Published in print edition: June, 2011