August 3, 2013

Hypocomplementemic Urticarial Vasculitis Syndrome in an 8-year-old Boy: A Case Report and Review of Literature


 

Hypocomplementemic Urticarial Vasculitis Syndrome in an 8-year-old Boy:
A Case Report
 and
Review of Literature
 

Zakiya Saleh Adnan Al Mosawi,1* and Badriya Ebrahim Ahmed Al Hermi2
 
 DOI 10.5001/omj.2013.76 
 
 
 
1MBBCh, ABMS-Pediatric, Pediatric Rheumatologist, Salmaniya Medical Complex, Kingdom of Bahrain.
2MBBCh, DCH (I), ABMS-Pediatric, Pediatric Nephrologist,Salmaniya Medical Complex, Kingdom of Bahrain.

Received: 21 Mar 2013
Accepted: 30 May 2013

*Address correspondence and reprints request to: Zakiya Saleh Adnan Al Mosawi, MBBCh, ABMS-Pediatric, Pediatric Rheumatologist, Salmaniya Medical Complex, 
Kingdom of Bahrain.
E-mail: zmosawi@health.gov.bh
 
 
 
 
Abstract
Hypocomplementemic urticarial vasculitis syndrome is an immune complex-mediated disease of unknown etiology. 
The clinical course is characterized by urticaria, conjunctivitis, joint pain, and hypocomplementemia. 
We here report a case of a child with hypocomplementemic urticarial vasculitis syndrome that progressed to nephritis. 
Renal biopsy was consistent with diffuse proliferative glomerulonephritis with diffuse subendothelial immune deposits. 
He responded well to a combination of steroid and mofetil micofenolate.
Keywords: HUVS; Nephritis; Children.

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