- Springer Open Choice
- PMC3725235
Current Allergy and Asthma Reports
Curr Allergy Asthma Rep. 2013; 13: 347–353.
Published online 2013 May 17. doi: 10.1007/s11882-013-0352-1
PMCID: PMC3725235
Abstract
Celiac disease (CD) is an autoimmune condition affecting the small intestine, triggered by the ingestion of gluten, the protein fraction of wheat, barley, and rye. There is a strong linkage between CD and HLA-DQ2 and HLA-DQ8 haplotypes. Multiple case reports and small series suggest concordance between CD and other autoimmune disorders. This paper provides a brief overview of the pathogenesis of CD and reviews the literature regarding associations between CD and other autoimmune diseases, including the potential effects of gluten-free diet therapy on the prevention or amelioration of associated diseases.
Keywords: Celiac, Celiac disease, Autoimmune, Addison’s disease, Addison’s, Type 1 diabetes, Autoimmune thyroiditis, Hashimoto’s thyroiditis, Graves disease, Cryptogenic hepatitis, Celiac hepatitis, Primary biliary cirrhosis, Sjogren’s syndrome, Systemic lupus erythematous, SLE, Lupus, Antiphospholipid syndrome, Psoriasis, Vitiligo, Alopecia acreta, Dermatitis herpetiformis
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