October 16, 2013

Erosive nappy erythema following sunitinib intake

Logo of pamj
Pan Afr Med J. 2013; 14: 46.
Published online 2013 February 1. doi:  10.11604/pamj.2013.14.46.2235
PMCID: PMC3612905

Image in medicine

We report on the case of a 54 years old man treating for a metastatic renal carcinoma who had experienced a dermatological toxicity referring to sunitinb intake. The antiangiogenic drug was delivered at a daily dose of 50mg for 4 weeks followed by two weeks of rest. By the second week of treatment the patient presented a nappy erythema evolving towards erosive lesions bleeding at mild friction and extending to the perianal and scrotal area, the process fulfilled the maximal intensity at 4 weeks and improved after the discontinuation of sunitinib. The patient refused the reintroduction of the drug. No skin biopsy was developed seeing that the lesions disappeared 4 weeks later. Figure 1
Figure 1
Erosive nappy erythema (A) and scrotal erythema (B)

Articles from The Pan African Medical Journal are provided here courtesy of African Field Epidemiology Network

Formats:

No comments:

Post a Comment