November 29, 2013

Beta-lactam allergy: clinical implications and costs

Open Access
Research


Giovanni SattaVictoria HillMarisa Lanzman and Indran Balakrishnan
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Clinical and Molecular Allergy 2013, 11:2  doi:10.1186/1476-7961-11-2
Published: 27 November 2013

Abstract (provisional)

Background

beta-lactam allergy is the most commonly reported medication allergy and it remains a key issue in antibiotic prescribing. A detailed and accurate history taking play a key role in preventing potentially serious clinical incidents and it may contribute in reducing costs.

Methods

Data were collected for patients with a documented penicillin allergy on their drug chart during a six month period. Sources included the inpatient drug charts and medical notes. Adherence to hospital guidelines was audited and costs of treatments were calculated.

Results

94 patients with a history of penicillin allergy were included. Compliance with the hospital antibiotic policy was 81% and 52% of cases had a description of the reaction documented. The mean additional cost per patient was [pound sign]89.29 (excluding VAT).

Conclusions

It is important to maintain a high level of vigilance and constantly educate all healthcare professionals involved in prescribing and dispensing antibiotics in order to avoid the unnecessary use of non-penicillin-based antibiotics and associated cost implication.

The complete article is available as a provisional PDF. The fully formatted PDF and HTML versions are in production.

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