- Yonsei Med J
- v.54(1); Jan 1, 2013
- PMC3521276
Yonsei Med J. 2013 January 1; 54(1): 262–264.
Published online 2012 November 28. doi: 10.3349/ymj.2013.54.1.262
PMCID: PMC3521276
A Case of Immunoglobulin E Mediated Anaphylaxis to Levodropropizine
Kyung Hee Park,1,2 Il Seon Yun,1,2 Soo-Young Choi,2 Jae-Hyun Lee,1,2 Chein-Soo Hong,1,2 and Jung-Won Park
1,2
1,2Abstract
We experienced a case of immunoglobulin E (IgE) mediated anaphylaxis to levodropropizine. The patient was an 18-year old Korean woman. After taking the common cold medication including acetaminophen, domperidone, and levodropropizine, skin rash, angioedema and anaphylaxis were developed immediately. As she was tolerable to acetaminophen alone, we thought the culprit agent was maybe a levodropropizine tablet. To confirm the culprit, she underwent skin prick test and oral drug provocation test with the suspected one. Finally we detected levodropropizine specific IgE and confirmed the specificity by inhibition enzyme-linked immunosorbent assay (ELISA).
Keywords: Levodropropizine, anaphylaxis, drug hypersensitivity
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Abstract
We experienced a case of immunoglobulin E (IgE) mediated anaphylaxis to levodropropizine. The patient was an 18-year old Korean woman. After taking the common cold medication including acetaminophen, domperidone, and levodropropizine, skin rash, angioedema and anaphylaxis were developed immediately. As she was tolerable to acetaminophen alone, we thought the culprit agent was maybe a levodropropizine tablet. To confirm the culprit, she underwent skin prick test and oral drug provocation test with the suspected one. Finally we detected levodropropizine specific IgE and confirmed the specificity by inhibition enzyme-linked immunosorbent assay (ELISA).
Keywords:
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