Development of allergic bronchopulmonary aspergillosis with central bronchiectasis over a 10-year period: the need to recheck allergen sensitization

Internal Medicine
Vol. 52 (2013) No. 18 p. 2135-2138

Language:      English     Japanese   

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http://dx.doi.org/10.2169/internalmedicine.52.0069

 

DN/JST.JSTAGE/internalmedicine/52.0069

CASE REPORTS

Yoshiko Yoshida^{1) 2)}, Toshihiro Shirai¹⁾, Masashi Mikamo¹⁾, Yuichiro Shishido¹⁾, Takefumi Akita¹⁾, Satoru Morita¹⁾, Kazuhiro Asada¹⁾,Masato Fujii¹⁾, Takafumi Suda³⁾

1) Department of Respiratory Medicine, Shizuoka General Hospital, Japan 2) Department of Respiratory Medicine, Numazu City Hospital, Japan 3) The Second Department of Internal Medicine, Hamamatsu University School of Medicine, Japan

 Released on J-STAGE 20130915  

Keywords: allergic bronchopulmonary aspergillosis, Aspergillus, central bronchiectasis, early diagnosis, 10-year period

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• Abstracts
• References(5)

A 55-year-old woman visited our hospital for an investigation of central bronchiectasis, mucoid impaction and infiltrative shadows on chest CT. She had a 10-year history of bronchial asthma; however, her adherence to treatment was poor. Based on the presence of peripheral blood eosinophilia and immediate cutaneous reactivity to Aspergillus fumigatus, the patient was clinically diagnosed with allergic bronchopulmonary aspergillosis. Her condition and CT findings improved with systemic corticosteroid therapy. It was found that the patient had not been sensitized to Aspergillus 10 years earlier, indicating that single testing is inadequate for the early diagnosis of this disease.

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Copyright © 2013 by The Japanese Society of Internal Medicine