Case Reports in Immunology
Volume 2014 (2014), Article ID 320920, 5 pages
http://dx.doi.org/10.1155/2014/320920
Case Report
1Division of Pediatric Rheumatology, Children’s Medical Center, Pediatrics Center of Excellence, Tehran 14194, Iran
2Pediatric Rheumatology Research Group, Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran
3Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran
4Research Center for Immunodeficiencies, Tehran University of Medical Sciences, Tehran, Iran
2Pediatric Rheumatology Research Group, Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran
3Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran
4Research Center for Immunodeficiencies, Tehran University of Medical Sciences, Tehran, Iran
Received 19 September 2014; Accepted 15 November 2014; Published 4 December 2014
Academic Editor: Ahmad M. Mansour
Copyright © 2014 Raheleh Assari et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
A 7-year-old boy with high grade fever (39°C) and warm, erythematous, and indurated plaque above the left knee was referred. According to the previous records of this patient, these indurated plaques had been changed toward abscesses formation and then spontaneous drainage had occurred after about 6 to 7 days, and finally these lesions healed with scars. In multiple previous admissions, high grade fever, leukocytosis, and a noticeable increase in erythrocyte sedimentation rate and C-reactive protein were noted. After that, until 7th year of age, he had shoulder, gluteal, splenic, kidney, and left thigh lesions and pneumonia. The methylprednisolone pulse (30 mg/kg) was initiated with the diagnosis of Sweet’s syndrome. After about 10–14 days, almost all of the laboratory data regressed to nearly normal limits. After about 5 months, he was admitted again with tachypnea and high grade fever and leukocytosis. After infusion of one methylprednisolone pulse, the fever and tachypnea resolved rapidly in about 24 hours. In this admission, colchicine (1 mg/kg) was added to the oral prednisolone after discharge. In the periodic fever and neutrophilic dermatosis, the rheumatologist should search for sterile abscesses in other organs.
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