Anaphylaxis due to caffeine

	Case Report  Open Access
	Asia Pac Allergy. 2015 Jan;5(1):55-56. English. Published online Jan 28, 2015.  http://dx.doi.org/10.5415/apallergy.2015.5.1.55  Copyright © 2015. Asia Pacific Association of Allergy, Asthma and Clinical Immunology. Kumiya Sugiyama,1,2 Tatsurai Cho,3 Masamitsu Tatewaki,1,2 Shogo Onishi,2 Tatsuya Yokoyama,2 Naruo Yoshida,1,2 Takayoshi Fujimatsu,1,2 Hirokuni Hirata,2 Takeshi Fukuda,2 and Yasutsugu Fukushima1,2 1Department of Respiratory Medicine, Dokkyo Medical University Koshigaya Hospital, Koshigaya 343-8555, Japan. 2Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University, Mibu 321-0293, Japan. 3Moka-Seibu Clinic, Moka 321-4364, Japan. Received May 15, 2014; Accepted January 07, 2015. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract We report a rare case of anaphylaxis due to caffeine intake. A 27-year-old woman suffered her first episode of anaphylaxis and a positive skin prick test suggested that the anaphylaxis was due to an IgE-mediated hypersensitivity reaction to caffeine. She was diagnosed with caffeine allergy and has not had an allergic reaction after avoiding foods and drinks containing caffeine. Although caffeine is known to have antiallergic effects, this case shows that caffeine can be an allergen and cause anaphylaxis. Keywords: Anaphylaxis, Caffeine, Food allergy.

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