Allergic reactions after vaccination: translating guidelines into clinical practice

A. Radice¹radiceanna87@gmail.com, G. Carli², D. Macchia¹, A. Farsi²   

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Doihttps://doi.org/10.23822/EurAnnACI.1764-1489.86

SummaryVaccination represents one of the most powerful medical interventions on global health.

Despite being safe, sustainable, and effective against infectious and in some cases also non-infectious diseases, it's nowadays facing general opinion's hesitancy because of a false perceived risk of adverse events. Adverse reactions to vaccines are relatively rare, instead, and those recognizing a hypersensitivity mechanism are even rarer.
The purpose of this review is to offer a practical approach to adverse events after vaccination, focusing on immune-mediated reactions with particular regard to their recognition, diagnosis and management.
According to clinical features, we propose an algorythm for allergologic work-up, which helps in confirming hypersensitivity to vaccine, nonetheless ensuring access to vaccination. Finally, a screening questionnaire is included, providing criteria for immunisation in specialized care settings.

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