July 13, 2020

The need for fast-track, high-quality and low-cost studies about the role of the BCG vaccine in the fight against COVID-19

  • Letter to the Editor
  • Open Access

Abstract

Bacillus Calmette-Guérin (BCG) vaccination is routine and near-universal in many low- and middle-income countries (LMIC). It has been suggested that BCG can have a protective effect on COVID-19 morbidity and mortality. This commentary discusses the limitations of the evidence around BCG and COVID-19. We argue that higher-quality evidence is necessary to understand the protective effect of the BCG vaccine from existing, secondary data, while we await results from clinical trials currently conducted in different settings.

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