Multidisciplinary Management of Pediatric Chronic Rhinosinusitis with Nasal Polyposis

Oh, E., Miller, J.E. & Lee, J.T. Curr Treat Options Allergy 11, 34–48 (2024). https://doi.org/10.1007/s40521-024-00362-z

Abstract

Purpose of review

This review explores the comprehensive management and treatment strategies for pediatric chronic rhinosinusitis with nasal polyps (CRSwNP). It addresses questions regarding the efficacy and safety of both current treatments and emerging therapies. Additionally, this paper examines the diagnostic challenges in pediatric CRSwNP, particularly its distinct presentations and characteristics compared to those in adults.

Recent findings

Current research highlights various approaches for treating pediatric CRSwNP. Intranasal corticosteroids are found to be effective in managing symptoms, while oral corticosteroids are used to manage severe cases.

Antibiotic therapy is recommended for acute exacerbations of CRSwNP when a bacterial cause is suspected. Surgical interventions such as adenoidectomy and endoscopic sinus surgery are considered when medical therapy fails. Emerging biologic therapies show promise but require further investigation regarding safety and cost-effectiveness in the pediatric population.

Summary

The findings suggest that a multimodal approach is essential for treating pediatric CRSwNP. Future research should aim to develop targeted therapies and refine treatment guidelines specifically for the pediatric population.

PDF